Association between lipid profile and silent coronary artery disease in south Indian patients with type 2 diabetes mellitus

Bhutto, Mehwish; Lokesh, M R; Shah, Sharath Kumar D.; M, Khizer Hussain Afroze; Ghouse, P; Abhilash, D

doi:10.18203/2349-3933.ijam20164020

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…A very high number of diabetics had hypercholesterolemia as compared to controls also described by. 11,[14][15] Triglycerides are considered as a separate risk factor for causing complexities of diabetes mellitus. Triacylglycerol were also significantly raised and linked with type 2 diabetic subjects as determined by.…”

Section: Discussionmentioning

confidence: 99%

Type 2 Diabetes Mellitus

Jan¹,

Saeed²,

Zia³

et al. 2018

TPMJ

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Developing countries like Pakistan have many sufferers of Diabetes Mellitus Type 2 still unprepared and unaware of the disastrous implications and complications of the disease. Local population must be aware about all factors that may worsen the disease or that may be monitored to keep them in a better status of health. Objectives: To assess the correlation between blood glucose and various parameters of lipid profile alongwith levels ofMagnesium in Type 2 diabetic patients. The aim was to help in better management of patients by monitoring dyslipidemia and mineral levels in Type2 diabetics. Study design: Cross sectional study. Setting: Madinah Teaching Hospital, Faisalabad. Period: 6 months from July to December 2017. Subjects and methods: The study was executed at Madinah Teaching Hospital Faisalabad on 50 known cases of diabetes mellitus type 2 as well as 30 healthy subjects. Estimations included Fasting blood glucose, Lipid profile and Serum Magnesium. All parameters were performed by Cobas C311 analyzer. Statistical analysis was done using SPSS version 20. Results: There was significant positive correlation between fasting blood sugar andserum cholesterol, triglycerides and LDL while a highly significant negative correlation existed between HDL and FBS. There was negative correlation among fasting blood sugar and serum Magnesium. The control group also showed low HDL and Magnesium levels. Conclusion: Hypercholesterolemia, hypertriglyceridemia, high LDL is associated with type 2 diabetes mellitus along with low HDL and hypomagnesaemia. The low levels in control group may be due to heredity or dietary factors.

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Section: Discussionmentioning

confidence: 99%

Type 2 Diabetes Mellitus

Jan¹,

Saeed²,

Zia³

et al. 2018

TPMJ

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Prevalence and Determinants of Dyslipidemia: Data from a Saudi University Clinic

Al-Hassan¹,

Fabella²,

Estrella³

et al. 2018

TOPHJ

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Background: Dyslipidemia is a risk factor for cardiovascular diseases. The relationship between demographic factors and dyslipidemia in Saudi Arabia is not completely explored. Objectives: This analytic cross-sectional study was conducted to describe the lipid profile, determine the proportion and identify significant demographic determinants of dyslipidemia among patients who have undergone lipid profile analysis in a university multispecialty clinic. Methods: The results of lipid profile examination of 1,541 King Faisal University clinic patients from 1 April, 2014 to 7 March, 2016 were compiled and subjected to descriptive and analytical statistics using STATA MP version 14. Multivariable logistic regression model using Adjusted Odds Ratio (AOR) and 95% Confidence Interval (CI) was fitted to analyze the independent predictors of dyslipidemia. Results: The prevalence of hypercholesterolemia, hypertriglyceridemia, hypo-HDL-cholesterolemia, and hyper-LDL-cholesterolemia were 13.8%, 17.0%, 40.0% 12.85%, respectively. Logistic regression revealed that in comparison with those who were 20 years old and below, those who were between the age of 40-49 years were 4.5 times more likely to have hypercholesterolemia and 3.5 times more likely to have hyper-LDL-cholesterolemia. Similarly, those who were 30-39 years old were 4.3 times and 3 times more likely to have hypertriglyceridemia and hypercholesterolemia, respectively. The same stage group was 3 times more likely to develop hyper-LDL-cholesterolemia. Females were 1.4 times more like to have hypercholesterolemia; non-Saudis were nearly twice as likely to develop hypertriglyceridemia than Saudis. Conclusion: Hypo-HDL-cholesterolemia was the most prevalent form of dyslipidemia. Age, gender and nationality were significant determinants of specific types of dyslipidemia.

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Association between lipid profile and silent coronary artery disease in south Indian patients with type 2 diabetes mellitus

Cited by 2 publications

References 7 publications

Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Prevalence and Determinants of Dyslipidemia: Data from a Saudi University Clinic

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