Association between health-related hope and adherence to prescribed treatment in CKD patients: multicenter cross-sectional study

Abstract

Background In chronic kidney disease (CKD), patients’ adherence to prescriptions for diet and for medications might depend on the degree to which they have hope that they will enjoy life, and that hope could vary with the stage of CKD. The aims of this study were to quantify both the association of CKD stage with health-related hope (HR-Hope), and the association of that hope with psychological and physiological manifestations of adherence. Methods This was a cross-sectional study involving 461 adult CKD patients, some of whom were receiving dialysis. The main exposure was HR-Hope, measured using a recently-developed 18-item scale. The outcomes were perceived burden of fluid restriction and of diet restriction, measured using the KDQOL, and physiological manifestations of adherence (systolic and diastolic blood pressure [BP], and serum phosphorus and potassium levels). General linear models and generalized ordered logit models were fit. Results Participants at non-dialysis stage 4 and those at stage 5 had lower HR-Hope scores than did those at stage 2 or 3 (combined). Those at non-dialysis stage 5 had the lowest scores. HR-Hope scores of participants at stage 5D were similar to those of participants at stage 4, but they were lower than the scores of participants at stage 2 or 3 (combined). Higher HR-Hope scores were associated with lower perceived burdens of fluid restriction and of diet restriction (adjusted ORs per ten-point difference were 0.82 and 0.84, respectively). Higher HR-Hope scores were associated with lower systolic BP (adjusted mean difference in systolic BP per ten-point difference in HR-Hope scores was − 1.87 mmHg). In contrast, HR-Hope scores were not associated with diastolic BP, serum phosphorus levels, or serum potassium levels. Conclusions Among CKD patients, HR-Hope is associated with disease stage, with psychological burden, and with some physiological manifestations of adherence.

Spiritual well‐being and its relationship with patient characteristics and other patient‐reported outcomes in peritoneal dialysis patients: Findings from the PDOPPS

“…Kurita et al used a health-related hope score in pre-and post-dialysis CKD patients and found that patients with higher hope to enjoy life were associated with lower perception of burden of fluid and diet restriction and better systolic blood pressure. 39 Furthermore, the correlations of SWB scores with HRQOL in our study were rather weak which supported the idea that SWB aspects of spirituality are distinct and separate constructs. In other words, it does not seem that spirituality has considerable overlap with other PRO parameters, suggesting that SWB is a unique dimension of HRQOL.…”

“…Nevertheless, there was a previous study from Japan supporting the idea that SWB may associate with improved HRQOL. Kurita et al used a health‐related hope score in pre‐ and post‐dialysis CKD patients and found that patients with higher hope to enjoy life were associated with lower perception of burden of fluid and diet restriction and better systolic blood pressure 39 . Furthermore, the correlations of SWB scores with HRQOL in our study were rather weak which supported the idea that SWB aspects of spirituality are distinct and separate constructs.…”

The association between sense of coherence and quality of life: a cross-sectional study in a sample of patients on hemodialysis

“…Moreover, further research is needed to ascertain if SOC is conceptually different from self-efficacy, hope, and resilience. This is an important question to address specifically in this patient-population, especially that, for example, studies have shown that hope is associated with a decreased burden of fluid and dietary restriction in dialysis patients [ 75 ] and is associated with a decreased incidence of the decline in physical function [ 76 ].…”

Trust in the attending rheumatologist, health-related hope, and medication adherence among Japanese patients with systemic lupus erythematosus: the TRUMP2-SLE project

“…To date, only a preventive role of hope for mental status, such as depression and anxiety, has been noted in patients with SLE. [18] Considering that high levels of hope may contribute to lower burden on self-management and better blood pressure control among patients with chronic kidney disease, [15] health-related hope may serve as a psychological factor that drives continuing successful self-management, regardless of the type of chronic disease.…”