Association between dietary exposure to bisphenols and body mass index in Spanish schoolchildren

Abstract

The increase in children obesity worldwide has been of particular concern in recent decades. Environmental factors have been proposed as contributors to obesity, and there is a growing concern over obesogens, environmental chemicals with potential obesity‐related endocrine‐disrupting properties. In this regard, bisphenol A (BPA) and its analogues are suspected to have obesogenic properties. Current document report on the activities of the fellow, undertaken during the fourth, 2020–2021 cycle of the EU‐FORA programme at the University of Granada, Institute of Nutrition and Food Science, in Spain. The work programme offered by the hosting site was related to the extrapolation of bisphenols exposure following the determination of these compounds in food frequently consumed by children and in their biological samples. The fellow has participated in the recruitment of the study population in the health centres. In addition, she has participated in the collection of the children biological samples, anthropometric measurements and dietary surveys and in the optimisation of the laboratory methodology for the extraction of bisphenols in biological samples. All these activities also provided the fellow an opportunity to develop her data science related skills, which will benefit her professional development. In addition, the fellow gained an overview of various topics related to food safety risk assessment by attending the EU‐FORA dedicated training modules.

Microbiota analysis for risk assessment of xenobiotics: cumulative xenobiotic exposure and impact on human gut microbiota under One Health approach

“…Microbial and molecular dysbiosis in the human gut microbiota has been related to the cumulative exposure to a wide variety of xenobiotic substances that act as EDCs through microbiota interaction and inducing obesogenic phenotypes (López‐Moreno et al., 2022 ). In the last decade, EDCs were revealed to also behave as obesogens, altering the endocrine system and leading to the onset of obesity (Stecca et al., 2022 ). EDCs are common in foods after their processing, packaging, transportation, and storage and prolonged exposure to EDCs might affect human health by triggering obesity, insulin resistance, metabolic syndrome and even infertility (Aguilera et al., 2021 ; Robles‐Aguilera et al., 2021 ).…”