Association between body mass index and pupillary light reflex indices

Autonomic tone in children and adults: Pupillary, electrodermal and cardiac activity at rest

“…First, some physiological parameters would need to be taken into consideration for futures studies, especially in the field of neurodevelopmental disorders. In particular, body mass index can differ from the typical population in ASD (Mouridsen et al, 2002) and is related to HRV parameters (Koenig et al, 2014;Molfino at al., 2009) but also to sympathetic influence on the pupillary activity (Segal et al, 2022). Moreover, without being linked to the sexual difference in corpulence, HRV differs according to gender as we observed in our study, see Supplementary Material) and would be, to a lesser degree, influenced by the menstrual cycle (Vallejo et al, 2005).…”

The impact of Alzheimer’s disease risk factors on the pupillary light response

“…Blüher et al assessed changes in the PLR of obese children, after exercise and lifestyle interventions were made to decrease BMI and found that reductions in BMI were associated with a higher dilation velocity, higher relative light reflex amplitude, and higher constriction velocity ( Blüher et al, 2015 ). Within a group of healthy adults with a range of BMIs ranging from normal to obese, Segal et al found that those with a higher BMI also had a higher average dilation velocity post-stimulus and concluded that BMI levels positively correlate with sympathetic activity ( Segal et al, 2022 ). When investigating sets of identical twins who had different BMIs (obese and non-obese classifications), Piha et al did not find significant differences in heart rate, blood pressure, or pupillary responses between the obese and non-obese twins and concluded that neither sympathetic nor parasympathetic responsiveness is significantly affected by obesity and instead is affected significantly by genetic factors ( Piha et al, 1994 ).…”