Association between albumin administration and survival in cardiac surgery: a retrospective cohort study

Kingeter, Adam J.; Raghunathan, Karthik; Munson, Sibyl H.; Hayashida, David K.; Zhang, Xuan; Iyengar, Sloka; Bunke, Martin; Shaw, Andrew

doi:10.1007/s12630-018-1181-4

Cited by 32 publications

(31 citation statements)

References 40 publications

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“…The low albumin has been associated with adverse outcomes in various other disease conditions [18][19][20][21][22][23], as well as in COVID-19 patients who were hospitalized [9,10,24]. Kheir et al concluded in their study that higher albumin level on admission was associated with favorable outcomes in hospitalized COVID-19 patients [11].…”

Section: Plos Onementioning

confidence: 99%

Low serum albumin and the risk of hospitalization in COVID-19 infection: A retrospective case-control study

et al. 2021

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Background The data on the COVID-19 patients who were discharged to self-quarantine is lacking. Aim The aim of the study was to investigate the percentage of COVID-19 positive patients that were hospitalized within a three-week period after discharge from ED to self-quarantine. Methods The patients who had confirmed SARS-CoV-2 on RT-PCR of the nasopharyngeal swab and were discharged from ED of a tertiary care hospital in the USA to self-quarantine from March 01- July 31, 2020, were included. Patients were divided into two groups based on serum albumin levels and were followed up for three weeks to see if low level of albumin increased the risk of hospitalization. Univariate and multivariate logistic regression analyses were performed to study the effect of albumin level and outcomes. Results A total of 112 patients were included in the study out of which 65 had low serum albumin (<3.5 g/dL) and 47 had normal serum albumin (≥3.5 g/dL). More than 10% of patients discharged to self-quarantine needed hospitalization within three weeks. The Low albumin group had more co-morbidities at baseline. The low serum albumin group had 10 (15.38%) vs 2 (4.26%), p = 0.06 hospitalizations as compared to the normal serum albumin group. The multivariate logistic regression analysis did not reveal lower odds of hospitalization in the group with normal albumin, (OR 0.26, 95% CI 0.03–1.92, p = 0.19) after controlling for age, sex, and various co-morbidities. Conclusion The low serum albumin was not associated with the risk of hospitalization in COVID-19 patients who were initially discharged to self-quarantine.

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Section: Plos Onementioning

confidence: 99%

Low serum albumin and the risk of hospitalization in COVID-19 infection: A retrospective case-control study

et al. 2021

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“…71,72 However, clear evidence of benefit is also lacking, and any benefits may be limited to specific patient populations. [73][74][75]…”

Section: Methods Of Fluid Administrationmentioning

confidence: 99%

Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

Ostermann

Bellomo

Burdmann

et al. 2020

Kidney International

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319

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I n 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the classification and management of acute kidney injury (AKI). 1 Since then, new evidence has emerged that has important implications for clinical practice. Large epidemiology studies and risk profiles for AKI have become available in adults and children, such as the AKI-Epidemiologic Prospective Investigation (AKI-EPI) study, 2 the 0by25 Initiative, 3 the Southeast Asia-AKI (SEA-AKI) study, 4 and the Assessment of Worldwide Acute Kidney Injury, Renal Angina, and Epidemiology (AWARE) 5 and Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) 6 studies. The effectiveness of the KDIGO recommendations in preventing AKI has been confirmed in small single-center randomized controlled trials (RCTs), such as the Prevention of AKI (PrevAKI) 7 and the

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“…The results from previous studies on cardiac surgical patients regarding mortality associated with type of fluid used are inconclusive. A retrospective study of 2,190 propensity matched cohort of cardiothoracic surgical patients demonstrated a lower in-hospital mortality and all-cause 30-day readmission with albumin use when compared with crystalloids ( 33 ). Another retrospective study that utilized a large database of 19,578 patients who underwent coronary artery bypass grafting surgery indicated lower all-cause mortality with albumin use (OR, 0.80; 95% CI, 0.67–0.96) ( 34 ).…”

Section: Discussionmentioning

confidence: 99%

“…by the study by Sedrakyan et al ( 34 ) may still confound their results. One of the previous studies also excluded patients with missing data ( 33 ) but do not report this proportion of patients, and the other ( 34 ) does not mention missing data at all. Further, the exact indications (e.g., hypotension, low urine output, low central venous pressure, and high lactate) for albumin use could not be determined due to the retrospective nature of our study.…”

Section: Discussionmentioning

confidence: 99%

Albumin Use After Cardiac Surgery

Matebele

Ramanan

Thompson

et al. 2020

Critical Care Explorations

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Association between albumin administration and survival in cardiac surgery: a retrospective cohort study

Cited by 32 publications

References 40 publications

Low serum albumin and the risk of hospitalization in COVID-19 infection: A retrospective case-control study

Low serum albumin and the risk of hospitalization in COVID-19 infection: A retrospective case-control study

Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

Albumin Use After Cardiac Surgery

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