Association between adverse childhood experiences and brain volumes among Japanese community-dwelling older people: Findings from the NEIGE study

Koyama, Yuna; Fujiwara, Takeo; Murayama, Hiroshi; Machida, Masaki; Inoue, Shigeru; Shobugawa, Yugo

doi:10.1016/j.chiabu.2021.105456

Cited by 14 publications

(8 citation statements)

References 53 publications

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“…As elevated catastrophizing and threat perception is also associated with increased pain intensity (88), this would help to support subgroups at increased susceptibility to worse pain. Despite the advances in the psychoneuroimmunological understanding of ACEs, it is important to note that much evidence is based upon animal experimentation (104), limiting its potential extrapolation to human models. Concepts such as the role of cortical modulation or human psychology are not yet elucidated, and further investigation is required.…”

Section: Biological Mechanisms and Processesmentioning

confidence: 99%

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

et al. 2022

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Adverse childhood experiences (ACEs) increase the likelihood of reduced physical and psychological health in adulthood. Though understanding and psychological management of traumatic experiences is growing, the empirical exploration of ACEs and physical clinical outcomes remains under-represented and under-explored. This topical review aimed to highlight the role of ACEs in the experience of chronic pain, pain management services and clinical decision making by: (1) providing an overview of the relationship between ACEs and chronic pain; (2) identifying biopsychosocial mechanisms through which ACEs may increase risk of persistent pain; (3) highlighting the impact of ACEs on patient adherence and completion of pain management treatment; and (4) providing practical clinical implications for pain management. Review findings demonstrated that in chronic pain, ACEs are associated with increased pain complications, pain catastrophizing and depression and the combination of these factors further heightens the risk of early treatment attrition. The pervasive detrimental impacts of the COVID-19 pandemic on ACEs and their cyclical effects on pain are discussed in the context of psychological decline during long treatment waitlists. The review highlights how people with pain can be further supported in pain services by maintaining trauma-informed practices and acknowledging the impact of ACEs on chronic pain and detrimental health outcomes. Clinicians who are ACE-informed have the potential to minimize the negative influence of ACEs on treatment outcomes, ultimately optimizing the impact of pain management services.

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Section: Biological Mechanisms and Processesmentioning

confidence: 99%

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

et al. 2022

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“…ACEs is considered to affect life-course health via disparate biological mechanisms, including, but not limited to, the hypothalamic-pituitary-adrenal axis, DNA methylation in key genes, telomere length shortening, increased cortisol levels, and chronic inflammation ( Furman et al, 2019 ; Lang et al, 2020 ). A rising number of empirical studies have shown a positive association between ACEs and life-course health in North America, European countries, Africa, and Asia ( Bellis et al, 2019 ; El Mhamdi et al, 2017 ; Furman et al, 2019 ; Goodman et al, 2022 ; Herrmann et al, 2018 ; Iob et al, 2020 ; Jin & Liu, 2018 ; Koyama et al, 2022 ; Lang et al, 2020 ; Mlouki et al, 2023 ; Monnat & Chandler, 2015 ; Poole et al, 2017 ; Shonkoff & Garner, 2012 ; Tan & Mao, 2023 ; Tani et al, 2021 ). Health consequences cover both physical health (including general health, morbidity and mortality of cancer, cardiovascular disease, and respiratory diseases) and mental health (including depression and cognitive impairment) at a later age ( Dannefer, 2020 ; Sieber et al, 2020 ; Verropoulou & Serafetinidou, 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Social contexts and cross-national differences in association between adverse childhood experiences and frailty index

Wang¹

2023

SSM - Population Health

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“…The sex comparisons presented in Figure 4 show that males were 1.25 (95% CI = 1.00, 1.54, 95% PI = 0.47, 3.35, I 2 = 98.0%) times more likely than females to be childhood victims of physical domestic and family violence. This did not change after removing the three samples with the most unstable estimates (Koyama et al, 2022;Ramiro et al, 2010;Tsuboi et al, 2015) (OR = 1.28 [95% CI = 1.04, 1.59, 95% PI = 0.49, 3.36, I 2 = 98.0%]). Separate analyses by region indicate that males were significantly more likely than females to be childhood victims of physical domestic and family violence in East Asia (k = 2; OR = 2.17 [95% CI = 1.35, 3.45, I 2 = 93.0%]) and Europe (k = 5; OR = 1.18 [95% CI = 1.02, 1.35, 95% PI = 0.80, 1.74, I 2 = 34.0%]) only.…”

Section: Proportional Meta-analysis: Victimmentioning

confidence: 96%

“…The sex comparisons presented in Figure 6 indicate there was no significant difference between the proportion of females and males who witnessed physical domestic and family violence during childhood (OR = 1.03 [95% CI = 0.88, 1.22, 95% PI = 0.50, 2.13, I 2 = 96.0%]). This did not change when excluding the three samples with the most unstable estimates (Koyama et al, 2022;McLafferty et al, 2018;Ujhelyi Nagy et al, 2019) (OR = 1.01 [95% CI = 0.84, 1.20, 95% PI = 0.47, 2.19, I 2 = 97.0%]). Separate analyses by region indicate that the odds of witnessing physical domestic and family violence during childhood was greater for girls than boys in North America (k = 4; OR = 1.31 [95% CI = 1.14, 1.50, 95% PI = 0.67, 2.58, I 2 = 93.0%]) only.…”

Section: Table 1 (Continued)mentioning

confidence: 96%

Global Prevalence of Childhood Exposure to Physical Violence within Domestic and Family Relationships in the General Population: A Systematic Review and Proportional Meta-Analysis

Whitten

Tzoumakis

Green

et al. 2023

Trauma, Violence, & Abuse

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Efforts to identify and prevent childhood exposure to physical violence within domestic and family relationships must be underpinned by reliable prevalence estimates to ensure the appropriate allocation of resources and benchmarks for assessing intervention efficacy. We conducted a systematic review and meta-analysis of the global prevalence of childhood exposure to physical domestic and family violence separately as a victim or witness. Searches were conducted in Criminal Justice Abstracts, Embase, Scopus, PubMed, PsychInfo, and Google Scholar. Studies were included if they were peer-reviewed, published in English, had a representative sample, unweighted estimates, and were published between January 2010 and December 2022. One-hundred-and-sixteen studies comprising 56 independent samples were retained. Proportional meta-analysis was conducted to calculate the pooled prevalence for each exposure. Pooled prevalence estimates were also stratified by region and sex. The global pooled prevalence of childhood exposure to physical domestic and family violence as a victim or witness was 17.3% and 16.5%, respectively. Prevalence estimates were highest in West Asia and Africa (victim = 42.8%; witness = 38.3%) and lowest for the Developed Asia Pacific region (victim = 3.7%; witness = 5.4%). Males were 25% more likely than females to be the victim of physical domestic and family violence during childhood, while both were equally likely to have witnessed it. These findings suggest that childhood exposure to domestic and family violence is relatively common, affecting around one-in-six people by 18 years of age globally. Regional variations in prevalence estimates may reflect underlying economic conditions, cultural norms, and service availability.

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Association between adverse childhood experiences and brain volumes among Japanese community-dwelling older people: Findings from the NEIGE study

Cited by 14 publications

References 53 publications

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

The Influence of Adverse Childhood Experiences in Pain Management: Mechanisms, Processes, and Trauma-Informed Care

Social contexts and cross-national differences in association between adverse childhood experiences and frailty index

Global Prevalence of Childhood Exposure to Physical Violence within Domestic and Family Relationships in the General Population: A Systematic Review and Proportional Meta-Analysis

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