Associação entre Infecção por Heicobacter Pylori e Hipertensão Arterial Sistêmica: Metanálise

Huang, Mengyun; Zhu, Lijun; Jin, Yuelong; Fang, Zhengmei; Yao, Yingshui

doi:10.36660/abc.20200186

Cited by 7 publications

(3 citation statements)

References 35 publications

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“…It is closely related to both GI and extra‐GI diseases. 3 , 4 , 24 In the whole‐age stage, regardless of whether the infected person has accompanying symptoms or not, H. pylori eradication may prevent the occurrence of GC. 25 , 26 , 27 If H. pylori cannot be eradicated, the infection will continue for life.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of triple therapy containing berberine hydrochloride, amoxicillin, and rabeprazole in the eradication of Helicobacter pylori

Chen

et al. 2022

J of Digest Diseases

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Objective To estimate the effectiveness and safety of triple therapy containing berberine, amoxicillin, and rabeprazole in the eradication of Helicobacter pylori (H. pylori). Methods This prospective, randomized controlled, open‐label, noninferiority trial included treatment‐naive patients with H. pylori infection who were randomly allocated at a ratio of 1:1 into the berberine triple therapy group (berberine hydrochloride 300 mg thrice daily, amoxicillin 1 g twice daily, and rabeprazole 10 mg twice daily) or standard bismuth‐containing quadruple therapy group (amoxicillin 1 g twice daily, rabeprazole 10 mg twice daily, clarithromycin 500 mg twice daily, and bismuth tartrate 200 mg twice daily) for 14 days. Negative 13C/14C‐urea breath test at 4 weeks after completion of the therapy was regarded as successful eradication. Results Altogether 262 and 262 patients received berberine triple therapy and bismuth‐containing quadruple therapy, respectively. Both intention‐to‐treat (79.8% vs 80.9%, P = 0.742) and per‐protocol analyses (83.6% and 85.1%, P = 0.636) showed comparable eradication rate between the two groups, indicating a noninferior eradication rate (the lower limit of the 95% confidence interval over −10% [−7.9% and −7.87%, respectively]). Adverse events more commonly occurred in the bismuth‐containing quadruple‐therapy group (8.8% vs 16.0%, P = 0.012), while patient compliance and symptom improvement of the two regimens were comparable. Conclusion Triple therapy containing berberine, amoxicillin and rabeprazole is noninferior to bismuth‐containing quadruple therapy in the initial treatment for H. pylori eradication.

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Section: Discussionmentioning

confidence: 99%

Efficacy and safety of triple therapy containing berberine hydrochloride, amoxicillin, and rabeprazole in the eradication of Helicobacter pylori

Chen

et al. 2022

J of Digest Diseases

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“…Dysfunctional vascular endothelium is an etiological factor for hypertension. Additionally, HP infection can affect the immune system and induce autoimmune reactions, which may also cause hypertension ( Huang et al, 2021 ). The colonization of HP has been detected in the arterial wall ( Kowalski, 2001 ).…”

Section: Survey Methodologymentioning

confidence: 99%

Recent research progress on the correlation between metabolic syndrome and Helicobacter pylori infection

Xie

Zhou

et al. 2023

PeerJ

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Background Globally, metabolic syndrome (MS) and Helicobacter pylori (HP) infection, which have gained an epidemic status, are major challenges to human health, society, and medical professionals. Recent studies have demonstrated that MS is closely related to HP infection. Additionally, HP is an important risk factor for gastric cancer. However, systematic reviews on HP are lacking. This review aimed to summarize and analyze the potential correlation of HP infection with MS and its components, as well as the underlying mechanism, to provide reference and strategies for clinical prevention and treatment. Methodology Previous studies examining the correlation between HP and MS since 1990 were retrieved from the PubMed, Web of Science, and Embase databases. The potential correlation between HP infection and MS and its components was comprehensively analyzed. The keywords “Helicobacter pylori,” “HP,” “metabolic syndrome,” “hypertension,” “obesity,” “diabetes,” or “dyslipidemia” were used in all fields. No language restrictions were imposed. Results MS was strongly correlated to HP infection. The inflammatory response and inflammatory factors produced during HP infection are important etiological factors for insulin resistance and MS. The co-occurrence of long-term chronic inflammation and immune dysfunction with MS may be the predisposing factor for HP infection. MS components, such as diabetes, hypertension, dyslipidemia, and obesity were also correlated with HP infection in one or both directions. Conclusions HP infection and MS may promote the pathogenesis of each other. The contribution of HP infection and MS to gastric cancer cannot be ruled out based on co-occurrence. The MS components diabetes and obesity may be bidirectionally correlated with HP infection.

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“…It is considered a global public health problem, leading to a multitude of serious complications [60]. A positive association with HP has been found, although no correlation was evident between the grades of hypertension and HP infection status [61][62][63].…”

Section: Cardio-vascular Diseasesmentioning

confidence: 99%

Extra Digestive Disease and Helicobacter pylori Infection

Avram,

Cornelia Lazăr,

Olariu

2024

Helicobacter Pylori Infection - An Up to Date on the Pathogenic Mechanisms, Diagnosis and Clinical Management

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Helicobacter pylori infection has been associated with gastric pathology and gastric oncogenesis for many years, but its extra-digestive implications are less known. This chapter aims to provide up-to-date information on its potential role in neurological disease (Alzheimer’s disease, stroke, multiple sclerosis, Parkinson’s disease), dermatological disease (urticaria, rosacea, psoriasis), ophthalmological disease (glaucoma, chorioretinitis, blepharitis), hematologic disease (anemia, thrombocytopenia, neutropenia), as well as cardio-vascular disease (myocardial infarction, coronary atherosclerosis, hypertension), COVID-19, and metabolic pathology (diabetes mellitus, metabolic syndrome). For each group of diseases, a short description will be presented as well as information from published research. It will provide the reader with a global insight into the role of Helicobacter pylori in different pathologies.

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Associação entre Infecção por Heicobacter Pylori e Hipertensão Arterial Sistêmica: Metanálise

Cited by 7 publications

References 35 publications

Efficacy and safety of triple therapy containing berberine hydrochloride, amoxicillin, and rabeprazole in the eradication of Helicobacter pylori

Efficacy and safety of triple therapy containing berberine hydrochloride, amoxicillin, and rabeprazole in the eradication of Helicobacter pylori

Recent research progress on the correlation between metabolic syndrome and Helicobacter pylori infection

Extra Digestive Disease and Helicobacter pylori Infection

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