Assignment of the rat parathyroid hormone-like peptide gene (PTHLH) to chromosome 4: evidence for conserved synteny between human chromosome 12, mouse chromosome 6, and rat chromosome 4

Abstract

The gene coding for rat parathyroid hormone-like peptide (PTHLH) was previously assigned to rat chromosome 2 (Hendy et al., 1988). We reexamined this assignment. According to our results, the gene is on rat chromosome 4. Taking into account the known localizations of the KRAS2 (Kras-2) oncogene and the PTHLH gene, this assignment strongly suggests that a synteny group is conserved on rat chromosome 4, mouse chromosome 6, and human chromosome 12.

A Novel Retinal Degeneration Locus Identified by Linkage and Comparative Mapping of Canine Early Retinal Degeneration

“…The canine erd-linkage interval thus demonstrates considerable conserved synteny with readily identifiable regions of HSA12, BTA5, and MMU6. From other reports one can also extend this syntenic conservation to include regions on rat chromosome 4 (Szpirer et al, 1991), goat chromosome 5 (Hayes et al, 1993) and sheep chromosome 3 (Hayes et al, 1993).…”