Assessment of the Use of Anterior Segment Optical Coherence Tomography in Microbial Keratitis

Value of optical coherence tomography for anterior segment surgery

“…However, AS-OCT is capable of visualizing the cornea in great detail and objectively assessing microbial keratitis; along with slitlamp examination, it can be used to monitor the disease process. 41 Slit-scanning devices, such as Orbscan II (Bausch & Lomb), tend to underestimate corneal thickness in corneal opacities or haze due to scattering, which causes an incorrect identification of the corneal surface reflections. Corneal opacities, such as scars and opacities due to corneal degeneration or dystrophies, can be precisely mapped using AS-OCT, providing depth of the opacity and corneal thickness ( Figure 5).…”

Imaging in Ophthalmology

“…It is ideal for evaluating the depth of injury due to a foreign body, laceration or ocular burn [46]. In microbial keratitis, AS-OCT can illustrate corneal infiltrates as hyperreflective areas [47].…”

Limitations of Fourier-domain OCT

“…3,4 Figure 6 illustrates the poor penetration of shorter wavelength light. Fourier-domain OCT visualization of the Ahmed valve and ocular structures deeper than this is inferior to that with the Visante OCT.…”

“…[1][2][3][4][5] As far as we know, there are 3 commercially available spectral domain anterior segment modalities that do not require personal modifications: RTVue-100 (Optovue Inc.), Cirrus HD-OCT model 4000 (Carl Zeiss Meditec), and SOCT Copernicus HR (Optopol Technology SA).…”