Assessment of the toxic potential of graphene family nanomaterials

Abstract

Graphene, a single-atom-thick carbon nanosheet, has attracted great interest as a promising nanomaterial for a variety of bioapplications because of its extraordinary properties. However, the potential for widespread human exposure raises safety concerns about graphene and its derivatives, referred to as graphene-family nanomaterials. This review summarizes recent findings on the toxicological effects and the potential toxicity mechanisms of graphene-family nanomaterials in bacteria, mammalian cells, and animal models. Graphene, graphene oxide, and reduced graphene oxide elicit toxic effects both in vitro and in vivo, whereas surface modifications can significantly reduce their toxic interactions with living systems. Standardization of terminology and the fabrication methods of graphene-family nanomaterials are warranted for further investigations designed to decrease their adverse effects and explore their biomedical applications.

Supramolecular Structures as Carrier Systems Enabling the Use of Metal Ions in Antibacterial Therapy

“…Finding an easily accessible, cheap and efficient carrier is one of the most important challenges researchers are facing [11,12]. The carrier system presented here consists of a mixed supramolecular system of CR, which binds TY, which is a strong complexing agent for silver ions, by means of intercalation.…”

Genotoxicity and Cytotoxicity Assessment of Graphene Oxide Nanosheets on HT29 Cells

“…Studies have revealed their different biological properties in invitro and in-vivo conditions, which determine the role and application of nanomaterials (1).…”

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Graphene-based nanovehicles for photodynamic medical therapy

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