Solid-state fermentation has emerged as a potential technology for production of microbial products such as feed, fuel, food, industrial chemicals and pharmaceutical. This technology is worth of attention not only from researchers but also from industry, especially in the last two decades. Based on these aspects, a review of patents and scientific articles is presented to cover the application of solid-state fermentation on different areas, including process development, substrate and microorganism preparation, process modeling and design of bioreactors.A search done in the European Patent Office (EPO) [7] using the worldwide database, which includes a collection of published application from more than 90 countries, using the following keywords ("solid state fermentation" or "solid substrate fermentation") in title or abstract resulted in 399