Assessment of Tear Meniscus with Optical Coherence Tomography in Thyroid-Associated Ophtalmopathy

Altan-Yaycıoğlu, Rana; Bakıner, Okan; Bozkirli, Emre; Çoban-Karataş, Müge; Ulas, Burak

doi:10.3109/02713683.2013.847960

Cited by 15 publications

(11 citation statements)

References 27 publications

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Section: Tear Meniscusmentioning

confidence: 87%

“…Some metric variables of the menisci appeared to be reduced in the elderly and in patients with dry eye or thyroid-associated ophthalmopathy. Conversely, higher tear volume was found in MGD patients with corneal damage [47,[54][55][56]. However, although OCT imaging is capable of measuring quantitatively the tear meniscus in terms of height, depth, radius of curvature and area, none of these variables are predictive of the TF thickness [45].…”

Section: Tear Meniscusmentioning

confidence: 99%

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Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Napoli

Nioi

Mangoni

et al. 2020

JCM

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In the last few decades, the ocular surface and the tear film have been noninvasively investigated in vivo, in a three-dimensional, high resolution, and real-time mode, by optical coherence tomography (OCT). Recently, OCT technology has made great strides in improving the acquisition speed and image resolution, thus increasing its impact in daily clinical practice and in the research setting. All these results have been achieved because of a transition from traditional time-domain (TD) to Fourier-domain (FD) technology. FD-OCT devices include a spectrometer in the receiver that analyzes the spectrum of reflected light on the retina or ocular surface and transforms it into information about the depth of the structures according to the Fourier principle. In this review, we summarize and provide the state-of-the-art in FD-OCT imaging of the ocular surface system, addressing specific aspects such as tear film dynamics and epithelial changes under physiologic and pathologic conditions. A theory on the dynamic nature of the tear film has been developed to explain the variations within the individual compartments. Moreover, an integrative model of tear film behavior during the inter-blink period and visual fixation is proposed.

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Section: Tear Meniscusmentioning

confidence: 87%

Section: Tear Meniscusmentioning

confidence: 99%

Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Napoli

Nioi

Mangoni

et al. 2020

JCM

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“…Points on the grading scale that did not occur in any group are not shown. Palakuru et al 2007Palakuru et al , 2008Ibrahim et al 2010;Koh et al 2010;Chen et al 2011;Park et al 2012;Qiu et al 2012;Altan-Yaycioglu et al 2013;Fukuda et al 2013;Bartuzel et al 2014;Canan et al 2014;Sizmaz et al 2014;Akiyama et al 2015;Tukenmez-Dikmen et al 2015). For measuring precorneal tear film, the resolution of commercially available OCT systems is not sufficient for quantitative measurement.…”

Section: Discussionmentioning

confidence: 99%

Effect of different lubricant eye gels on tear film thickness as measured with ultrahigh‐resolution optical coherence tomography

Woźniak

Schmidl

Bata

et al. 2016

Acta Ophthalmologica

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“…In most studies, tear meniscus can be quantified by AS‐OCT in terms of tear meniscus height, tear meniscus depth, and tear meniscus area, measured directly after blinking . This enables a myriad of experimental data to be generated; for instance Sizmaz et al have shown that patients with Graves’ disease have lower tear meniscus height …”

Section: Resultsmentioning

confidence: 99%

Anterior segment optical coherence tomography and its clinical applications

Wang

Cornish

Grigg

et al. 2019

Clinical and Experimental Optometry

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Anterior segment optical coherence tomography (AS-OCT) has become one of the cornerstones of non-contact imaging modalities for assessing such structures as the cornea, anterior chamber angle, aqueous outflow pathway, sclera, and ocular surface structures. As such, it has a broad range of clinical applications, which have been independently reported in the literature. This paper aims to present a review of extant literature on the utility of AS-OCT and its efficacy in clinical applications, and to evaluate the quality of available evidence. The following databases were searched from inception to 24 June 2018: Medline via Ovid, Cochrane Central Register of Controlled Trials, PubMed, World Health Organization International Clinical Trials Registry Platform, EMBASE, and CINAHL. Bibliographies of identified papers were hand searched. Inclusion criteria: articles describing or assessing the use of OCT for visualising the AS. The authors excluded studies without an identified primary outcome variable. One author independently selected studies, extracted data, and assessed for risk of bias using PRISMA guidelines. This review included 82 studies, of which there were 11 cohort studies, 37 case series, 10 case studies, 21 comparative observational studies, and three non-systematic review articles. Primary outcome variables included anterior chamber angle, angle opening distance, angle recess area, trabecular iris angle, trabeculairis space area, corneal thickness, tear meniscus height, tear meniscus area, tear meniscus volume, and the morphology of AS structures, including the ocular surface, blebs, flaps, and graft sites. This review attempts to encompass the breadth and depth of evidence for AS-OCT in the arena of diagnostics, therapeutics, and prognostics. At the same time, it brings to light the dearth of high-level evidence on this topic, suggesting the important role of randomised controlled trials and meta-analyses for the future validation of this technology.

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Assessment of Tear Meniscus with Optical Coherence Tomography in Thyroid-Associated Ophtalmopathy

Abstract: Tear function is significantly disturbed in GD. OCT is an effective way to assess the tearing function also in patients with GD.

Cited by 15 publications

References 27 publications

Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Effect of different lubricant eye gels on tear film thickness as measured with ultrahigh‐resolution optical coherence tomography

Anterior segment optical coherence tomography and its clinical applications

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