Assessment of Sputum Quality and Its Importance in the Rapid Diagnosis of Pulmonary Tuberculosis

L, Mercy Aparna; Srikantam, Aparna; Sarada, I; Ram, Duvuru

doi:10.4172/1989-8436.100053

Cited by 16 publications

(8 citation statements)

References 14 publications

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“…Peppermint oil is widely used in folk remedies and traditional medicine to treat digestive disorders and nervous system problems because of its antitumor, chemopreventive, and antimicrobial properties, as well as its beneficial renal and antiallergenic effects [32][33][34]. It is also thought to be effective against cramping, digestive complaints, anorexia, nausea, and diarrhea [32,33]. Peppermint oil is composed of menthol and menthone, along with several other minor constituents [32].…”

Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

“…It is also thought to be effective against cramping, digestive complaints, anorexia, nausea, and diarrhea [32,33]. Peppermint oil is composed of menthol and menthone, along with several other minor constituents [32]. Although most peppermint research has been conducted on rat models, it is considered a medicinal plant for human diseases.…”

Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

“…Although most peppermint research has been conducted on rat models, it is considered a medicinal plant for human diseases. However, peppermint oil has also been found to cause cyst-like changes in the white matter of the cerebellum and nephropathy at overdoses of 40-100 mg/kg per day for 28-90 days [32]. In rats, 80 mg and 160 mg pulegone doses over 28 days caused atonia, weight loss, decreased blood creatinine, and histopathological changes in the liver and the white matter of the cerebellum.…”

Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

“…In rats, 80 mg and 160 mg pulegone doses over 28 days caused atonia, weight loss, decreased blood creatinine, and histopathological changes in the liver and the white matter of the cerebellum. Menthol was also observed to cause hepatocellular changes in rats [32]. During the Cosmetic Ingredient Review (CIR) Expert Panel Meeting, the panel expressed concern over oral dosing of peppermint oil, as some studies found evidence of pulegone-based toxicity [35].…”

Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

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Vapor Compounds Released from Nicotine-Free Inhalators as a Smoking-Cessation Aid

Kwak¹,

Han

Koren

et al. 2019

Applied Sciences

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The health risks of cigarette smoking have been reported to increase continuously, while it is estimated to be responsible for the death toll of more than seven million people globally each year. In an effort to reduce the risk involved in cigarette smoking, nicotine-free inhalators have been developed as smoking-cessation aids. To evaluate the feasibility of nicotine-free inhalators in such respect, we investigated the composition of volatile organic compounds (VOCs) released from the consumption of nicotine-free inhalators of which major components include natural essential oils and traditional Chinese medicinal herbs. Vapor samples from nicotine-free inhalators were generated and collected for analysis using an e-cigarette auto-sampler. The vapor samples were captured onto a multi-bed sorbent tube sampler and a 2,4-dinitrophenylhydrazine (DNPH) cartridge for the quantitative analysis with the aid of thermal desorption-gas chromatography/mass spectrometry and high-performance liquid chromatography, respectively. A total of 29 VOCs were determined in vapor samples at concentrations below 0.2 ppm. Concentrations of (+)-isomenthone and acrolein slightly exceeded the derived no-effect level (DNEL) or sensory irritation level. However, VOCs were below the concentration exposure limit, according to the Occupational Safety and Health Administration (OSHA). According to our study, most of the aroma compounds and VOCs released from nicotine-free inhalator were lower than the DNEL or sensory irritation level. Consequently, it is found that nicotine-free inhalators could be safe to use in reference to toxic guidelines for inhalation exposure. However, if the use of nicotine-free inhalators is over prolonged period, it can also increase the risk of exposure to potentially toxic compounds.

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Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

Section: Safety Of the Nicotine-free Inhalatormentioning

confidence: 99%

See 2 more Smart Citations

Vapor Compounds Released from Nicotine-Free Inhalators as a Smoking-Cessation Aid

Kwak¹,

Han

Koren

et al. 2019

Applied Sciences

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show abstract

“…Peppermint has been known to have gastric antiulcer effects that could be attributed to its compound. Peppermint compounds have been reported to have antioxidant and anti-inflammatory effects [9]. Menthone, as one of main compound in peppermint, seems to have an anti-inflammation and antioxidant compound that help to improve the gastric ulcers.…”

Section: Introductionmentioning

confidence: 99%

The Protective Role of Menthone Against Indomethacin-Induced Gastric Ulcers in Rat Model

2018

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The use of novel agents has been considered for management of different diseases. Gastric ulcer is a common disease. This study aimed to evaluate the effects of Menthone, as a novel agent, on gastric ulcers in Indomethacin-induced model rat. Materials and Methods: Animals were divided into 3 groups: 1. Control group that received only distilled water; 2. Animals were treated with 40 mg/kg bw omeprazole (Omeprazole); 3. Animals were treated with 40 mg/kg bw Menthone (Menthone). A single dose of indomethacin (30 mg/kg body weight) was administrated to per animal. Gastric secretions and antioxidant parameters were evaluated in the end of trial. Results: It was observed that an increased ulcer index, gastric volume, malondialdehyde level and decreased super oxide dismutase and pepsin activity in control group in comparison to other groups (P<0.05). The use of Menthone and Omeprazole could alleviate the effects of indomethacin. Conclusion: Menthone may not have positive effects similar to Omeprazole, but it could attenuate effects of indomethacin. We recommend using of Menthone, as an efficient agent, for treatment of gastric ulcer.

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Essential Oils as Potential Antimicrobial Agents

Varijakzhan

Yang

Chong

et al. 2021

Sustainable Agriculture Reviews

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Assessment of Sputum Quality and Its Importance in the Rapid Diagnosis of Pulmonary Tuberculosis

Cited by 16 publications

References 14 publications

Vapor Compounds Released from Nicotine-Free Inhalators as a Smoking-Cessation Aid

Vapor Compounds Released from Nicotine-Free Inhalators as a Smoking-Cessation Aid

The Protective Role of Menthone Against Indomethacin-Induced Gastric Ulcers in Rat Model

Essential Oils as Potential Antimicrobial Agents

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