Assessment of some heavy metals in vegetables, cereals and fruits in Saudi Arabian markets

Ali, Mahmoud Fadl; Al-Qahtani, Khairia M.

doi:10.1016/j.ejar.2012.08.002

Cited by 242 publications

(126 citation statements)

References 19 publications

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“…However, Cu levels in similar food samples were higher in China (38) and lower in Romania (39) and Libya (40) compared to our findings. Our results were also in agreement with the findings of Ali and Al-Qahtani who reported Cd, Pb, and Cu concentrations in vegetable samples, grown in the Kingdom of Saudi Arabia (29). The high concentration of Cd and Pb found in many samples might be nearly relevant to the contaminants in the irrigation water, farmland, and especially overuse of fertilizers and pesticides for the elimination of pests, weeds, and different accumulation capabilities of the tested vegetables and soil properties diversity (41).…”

Section: Discussionsupporting

confidence: 83%

Health Risk Assessment of Heavy Metals in Vegetables in an Endemic Esophageal Cancer Region in Iran

2018

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Background: Nowadays, the heavy metals pollution is increasing and the accumulation of these metals in food has posed adverse effects on humans such as inducing various kinds of cancer and non-cancer diseases. The Northeast of Iran, especially Torkman Sahra, has the maximum number of patients with esophageal cancer. Objectives: We investigated the levels of four heavy metals (Zn, Cd, Pb, and Cu) in cucumber and tomato samples in Golestan province, an endemic esophageal cancer region. We evaluated the levels and potential health risks of heavy metals in vegetable samples of Northeastern Iran. Methods: The heavy metal content of the samples was determined by polarography methods. All sample preparation and digestion procedures were carried out according to the Standard Methods for the Examination of Water and Wastewater, 20th Edition. Results:The results showed that Cd and Pb concentrations in cucumber and tomato were estimated to be respectively 2.4 to 14.4 and 1.6 to 7 folds higher whereas Zn and Cu levels were lower than the maximum permissible limit for vegetables. The amounts of Pb intake through the consumption of these vegetables were determined more than the provisional tolerable daily intake. The total non-cancer and cancer risk results indicated that the investigated region was relatively unsuitable for growing the vegetables in the view of the risk of the elevated intakes of heavy metals adversely affecting food safety for consumers. Pb was the heavy metal posing non-cancer risks while Cd caused the greatest cancer risk. Conclusions: It was concluded that due to the toxic effects of cadmium and lead, we should be more serious to reduce pollution levels in this region.

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Section: Discussionsupporting

confidence: 83%

Health Risk Assessment of Heavy Metals in Vegetables in an Endemic Esophageal Cancer Region in Iran

2018

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“…Copper toxicity can result in vomiting, diarrhea, hemolytic anemia, gastrointestinal bleeding, and multiple target organ failure (liver and kidneys), and is normally as a result of intake of contaminated water or contaminated foodstuffs, mostly as a result of industrial, domestic, and agricultural activities (Ali & Al‐Qahtani, 2012; Alturiqi & Albedair, 2012). Geographical location, hardness of water, and pH as well as the presence of copper piping (US National Academy of Science, 2000) affect increased copper levels, impacting on commercially important stocks of fish and crustaceans, as well as their biodiversity (Solomon, 2009).…”

Section: Discussionmentioning

confidence: 99%

Acute exposure to organic and inorganic sources of copper: Differential response in intestinal cell lines

Keenan

O’Sullivan

Henry

et al. 2018

Food Science & Nutrition

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ScopeCopper supplementation in nutrition has evolved from using inorganic mineral salts to organically chelated minerals but with limited knowledge of the impact at the cellular level.MethodsHere, the impact of inorganic and organic nutrient forms (glycinate, organic acid, and proteinate) of copper on the cellular level is investigated on intestinal cell lines, HT29 and Caco‐2, after a 2‐hr acute exposure to copper compounds and following a 10‐hr recovery.ResultsFollowing the 10‐hr recovery, increases were observed in proteins involved in metal binding (metallothioneins) and antioxidant response (sulfiredoxin 1 and heme oxygenase 1), and global proteomic analysis suggested recruitment of the unfolded protein response and proteosomal overloading. Copper organic acid chelate, the only treatment to show striking and sustained reactive oxygen species generation, had the greatest impact on ubiquitinated proteins, reduced autophagy, and increased aggresome formation, reducing growth in both cell lines. The least effect was noted in copper proteinate with negligible impact on aggresome formation or extended growth for either cell line.ConclusionThe type and source of copper can impact significantly at the cellular level.

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“…Vegetables are important components of the human diet, as rich sources of vitamins, minerals, fibre as well as their beneficial antioxidant effects (Ali and Al-Qahtani, 2012). The uptake and bioaccumulation of metals and metalloids in plant species are influenced by a number of different factors such as climate, atmospheric depositions, background geology and soil composition, the vicinity of roads and industry, as well as the degree of maturity of the plants at the time of harvest (Lake et al, 1984;Votusa et al, 1996).…”

Section: Introductionmentioning

confidence: 99%

Assessment of essential and nonessential dietary exposure to trace elements from homegrown foodstuffs in a polluted area in Makedonska Kamenica and the Kočani region (FYRM)

Vrhovnik¹,

Dolenec

Serafimovski

et al. 2016

Science of The Total Environment

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The main purpose of the present study is to assess human dietary exposure to essential and non-essential trace elements via consumption of selected homegrown foodstuffs. Twelve essential and non-essential trace elements (Cd, Co, Cu, Cr, Hg, Mo, Ni, Pb, Sb, Se, Zn and As) were detected in various homegrown foodstuffs. Detailed questionnaires were also applied among a sample of the local population to collect information on sociodemographic characteristics. The results of the present study clearly indicate that the majority of the trace elements are at highly elevated levels in the studied foodstuffs, in comparison to international recommendations. The maximum measured levels of ETE and NETE are as follows [μg kg −1 ]: Cd 873, Co 1370, Cu 21700, Cr 59633, Hg 26, Mo 6460, Ni14.5, Pb 11100, Sb 181, Se 0.30, Zn 102 and As 693. Additionally, age, body mass index and gender were significantly associated with levels of dietary exposure. Further research is warranted on the potential health implication of this exposure. Capsule abstract: The study merges the accumulation of ETE and NETE in home-grown foodstuffs and reflects considerably high health risks for inhabitants.

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Assessment of some heavy metals in vegetables, cereals and fruits in Saudi Arabian markets

Cited by 242 publications

References 19 publications

Health Risk Assessment of Heavy Metals in Vegetables in an Endemic Esophageal Cancer Region in Iran

Health Risk Assessment of Heavy Metals in Vegetables in an Endemic Esophageal Cancer Region in Iran

Acute exposure to organic and inorganic sources of copper: Differential response in intestinal cell lines

Assessment of essential and nonessential dietary exposure to trace elements from homegrown foodstuffs in a polluted area in Makedonska Kamenica and the Kočani region (FYRM)

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