Assessment of renal impairment by non-contrast-enhanced conventional magnetic resonance imaging: comparison with 99mTc-DTPA renography

Hidaka, Fumitaka; Amano, Yasuo; Takahama, Katsuya; Takagi, Ryo; Murakami, Ryusuke; Onozawa, Shiro; Kumita, Shin‐ichiro

doi:10.1007/s11604-011-0567-9

Cited by 6 publications

(6 citation statements)

References 30 publications

(40 reference statements)

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“…14 Our present results in patients with CKD without liver cirrhosis are consistent with this previous result.…”

Section: Discussionsupporting

confidence: 93%

“…Second, we excluded patients with apparent asym- metry of the kidneys because SKGFR was not estimated using a nuclear medicine study or perfusion MR imaging. 1,14 We cannot therefore extrapolate our present results to patients with CKD who have unilateral renal atrophy. Third, the observers were not completely blinded to whether the subjects belonged to the group with cirrhosis or the comparative group because liver cirrhosis was often obvious on the T 1 -weighted images.…”

Section: Discussionmentioning

confidence: 78%

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Pseudonormal Corticomedullary Differentiation of the Kidney Assessed on T<sub>1</sub>-weighted Imaging for Chronic Kidney Disease Patients with Cirrhosis

Yamada

Amano

Hidaka

et al. 2015

MRMS

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Purpose: We investigated whether corticomedullary differentiation (CMD) increased to a pseudonormal appearance on T 1 -weighted magnetic resonance (MR) images in patients with chronic kidney disease (CKD) with cirrhosis compared with patients with CKD without chronic liver disease.Methods: We assessed CMD on T 1 -weighted MR images of 32 patients with CKD with liver cirrhosis and 32 age-matched patients with CKD without liver cirrhosis, grading CMD visualization as good, moderate, or poor. We calculated quantitative CMD by the ratio of the signal intensity of the cortex to that of the medulla.Results: The proportions of patients in each of the good, moderate, and poor groups differed significantly between those with and without liver cirrhosis (P = 0.048). In patients with CKD with liver cirrhosis, the estimated glomerular filtration rate (eGFR) differed between those with poor CMD and those with good or moderate CMD (P < 0.01) but not between those with good and those with moderate CMD. In patients with CKD without cirrhosis, the eGFR differed significantly among the good, moderate, and poor CMD groups (P < 0.05). We observed no significant correlation between CMD and eGFR in patients with and without cirrhosis (P < 0.05, r = 0.62).Conclusion: CMD of the kidney had a pseudonormal appearance on T 1 -weighted MR imaging in patients with CKD with cirrhosis.

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“…14 Our present results in patients with CKD without liver cirrhosis are consistent with this previous result.…”

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 78%

Pseudonormal Corticomedullary Differentiation of the Kidney Assessed on T<sub>1</sub>-weighted Imaging for Chronic Kidney Disease Patients with Cirrhosis

Yamada

Amano

Hidaka

et al. 2015

MRMS

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“…Third, CMD as observed on the T1-weighted images was defined as good, moderate, or poor, based on previous studies as follows: good, CMD was visualized clearly throughout the kidney; moderate, CMD was partially lost in the kidney; poor, CMD was diminished. [12,13] The CMD was compared with renal function in these older patients with GCK. A kappa analysis was used to evaluate the radiologists’ assessment of CMD.…”

Section: Methodsmentioning

confidence: 99%

“…[5,10,11] In these studies, T1-weighted MRI detects renal impairment as the loss of corticomedullary differentiation (CMD). [10,12] Therefore, MRI may be an ideal imaging tool for identifying GCK. We identified 13 older patients with GCK during routine abdominal MRI.…”

Section: Introductionmentioning

confidence: 99%

Glomerulocystic kidney identified in older patients by magnetic resonance imaging

Amano

Omori²,

Yanagisawa³

et al. 2019

Medicine

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Glomerulocystic kidney (GCK) is often associated with genetic disorders and identified in children or adolescents. However, there are some case reports describing sporadic adult GCK identified by magnetic resonance imaging (MRI). The purpose of this study was to evaluate relationship of GCK identified by MRI in older patients to renal function and renal corticomedullary differentiation (CMD) assessed by MRI.GCK was identified in 16 older patients (mean age, 79.2 years) by T2-weighted imaging. The cysts of GCK were numerous, homogeneously small, and located in the renal cortex on T2-weighted images. Ten of the 16 patients with GCK had renal impairment (estimated glomerular filtration rate <60 ml/min/1.73 m2). Six patients who had GCK, chronic liver disease, and renal impairment showed moderate or good CMD.GCK identified by MRI may be related to renal impairment in some older patients, including those with preserved CMD as a result of chronic liver diseases.

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“…2 Meanwhile, renal cortical volumes and cortical thicknesses have been found to correlate with renal function. [6][7][8][9][10][11][12][13] It has been reported that non-contrast-enhanced steady-state free precession (SSFP) MRI with a spatially selective inversion recovery (IR) pulse can emphasize the difference in T 1 values between the renal cortex and the medulla by suppressing the background signal and the target tissue signal. Therefore, compared with conventional MRI sequences, this technique can improve the visualization of renal corticomedullary differentiation and facilitate the measurement of renal cortical thickness even in patients with renal dysfunction compared with conventional MRI sequences.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of renal cortical thickness by non-contrast-enhanced MR imaging with spatially selective IR pulses: comparison between cirrhotic and non-cirrhotic patients

Kanki

Ito

Yamamoto

et al. 2016

BJR

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Objective: To compare renal cortical thicknesses between patients with and without cirrhosis with normal renal function based on serum creatinine using noncontrast-enhanced steady-state, free precession (SSFP) MRI with spatially selective inversion recovery (IR) pulses and to discuss the clinical implications of measuring renal cortical thickness in patients with cirrhosis. Methods: 40 patients with and without cirrhosis who had normal renal function based on serum creatinine and underwent non-contrast-enhanced SSFP imaging with spatially selective IR pulses were included. The renal cortical thickness, renal width, renal cortical width ratio, serum creatinine levels and estimated glomerular filtration rates (eGFRs) were compared between cirrhotic and non-cirrhotic groups.

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Assessment of renal impairment by non-contrast-enhanced conventional magnetic resonance imaging: comparison with 99mTc-DTPA renography

Abstract: Non-contrast-enhanced MRI was capable of distinguishing three levels of renal function, including serious renal impairment.

Cited by 6 publications

References 30 publications

Pseudonormal Corticomedullary Differentiation of the Kidney Assessed on T<sub>1</sub>-weighted Imaging for Chronic Kidney Disease Patients with Cirrhosis

Pseudonormal Corticomedullary Differentiation of the Kidney Assessed on T<sub>1</sub>-weighted Imaging for Chronic Kidney Disease Patients with Cirrhosis

Glomerulocystic kidney identified in older patients by magnetic resonance imaging

Evaluation of renal cortical thickness by non-contrast-enhanced MR imaging with spatially selective IR pulses: comparison between cirrhotic and non-cirrhotic patients

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