Assessment of renal and hepatic dysfunction by co-exposure to toxic metals (Cd, Pb) and fluoride in people living nearby an industrial zone

Mélila, Mamatchi; Rajendran, R.; Arumugam, G; Kpemissi, Mabozou; Pakoussi, Tcha; Agbere, Sadikou; Lazar, Iulia M.; Lazăr, Gabriel; Amouzou, Komla Séna; Paray, Bilal Ahamad; Gulnaz, Aneela

doi:10.1016/j.jtemb.2021.126890

Cited by 18 publications

(3 citation statements)

References 37 publications

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“…TMs, due to their tendency to bioaccumulate, are found to be very hard to metabolize in an organism. Various studies reported that TMs can negatively influence a great spectrum of human organs such as the lungs [ 164 ], bladder [ 165 ], heart [ 166 , 167 ], kidney, and liver [ 168 ], and can be responsible for exhibiting anti-androgenic activity [ 169 ] and induce haematological and histopathological changes [ 170 ]. Therefore, TMs have been classified in the top 20 list of dangerous substances by ATSDR [ 171 ].…”

Section: Environment As a Source Of Bread Chemical Contaminantsmentioning

confidence: 99%

Chemical Contamination in Bread from Food Processing and Its Environmental Origin

Maher

Nowak²

2022

Molecules

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Acrylamide (AA), furan and furan derivatives, polycyclic aromatic amines (PAHs), monochloropropanediols (MCPDs), glycidol, and their esters are carcinogens that are being formed in starchy and high-protein foodstuffs, including bread, through baking, roasting, steaming, and frying due to the Maillard reaction. The Maillard reaction mechanism has also been described as the source of food processing contaminants. The above-mentioned carcinogens, especially AA and furan compounds, are crucial substances responsible for the aroma of bread. The other groups of bread contaminants are mycotoxins (MTs), toxic metals (TMs), and pesticides. All these contaminants can be differentiated depending on many factors such as source, the concentration of toxicant in the different wheat types, formation mechanism, metabolism in the human body, and hazardous exposure effects to humans. The following paper characterizes the most often occurring contaminants in the bread from each group. The human exposure to bread contaminants and their safe ranges, along with the International Agency for Research on Cancer (IARC) classification (if available), also have been analyzed.

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Section: Environment As a Source Of Bread Chemical Contaminantsmentioning

confidence: 99%

Chemical Contamination in Bread from Food Processing and Its Environmental Origin

Maher

Nowak²

2022

Molecules

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“…The most well-known toxicity of the prolonged dietary intake of Cd through rice is itai-itai disease in Japan [13]. The other toxic effects of long-term Cd exposure include kidney failure, reproductive organs impairment, immune system damage, cardiovascular diseases, and prostate, ovarian, and renal carcinogenicity in humans [6,[14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Agricultural Strategies to Reduce Cadmium Accumulation in Crops for Food Safety

Mubeen

2023

Agriculture

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Cadmium (Cd) contamination in edible agricultural products, especially in crops, has raised worldwide concerns regarding food safety consumption. This review summarizes the current knowledge of the applicable methods and perspectives for reducing Cd contamination of agricultural products. Agricultural approaches of soil amendments, irrigation management, microbial agent, and cropping patterns were systematically concluded to illustrate the developments and achievements in crop contamination management. The use of traditional soil amendments as well as novel nano-materials has contributed to producing safe crops in agricultural soil contaminated with Cd. This review provides an inspiring and promising tool for maintaining food safety by reducing Cd accumulation in edible agricultural products

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“…Thus, the consumption of seafood in general and fish in particular is the main exposure route to heavy metals 9 – 11 . Exposure to heavy metals including lead (Pb), cadmium (Cd) and mercury (Hg) can lead to a number of adverse health effects, including a compromised renal and hepatic function 12 , teratogenic effects 13 – 15 , and cognitive impairments 16 , 17 .…”

Section: Introductionmentioning

confidence: 99%

Assessment of health risks associated with heavy metal concentration in seafood from North-Western Croatia

Traven,

Marinac-Pupavac,

Žurga

et al. 2023

Sci Rep

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The following study aims at assessing the health risks associated with the consumption of the most commonly consumed seafood in the north-western part of Croatia due to the presence of heavy metals. Samples of seafood were collected and analysed for lead (Pb), cadmium (Cd), and mercury (Hg) content. Analyses of Cd and Pb were carried out by inductively coupled plasma mass spectrometry (ICP-MS) whereas Hg content was measured using atomic absorption spectrometry (AAS). Metal concentrations were in the following order Hg > Pb > Cd for the gilthead seabream, European hake, sardines, and tuna fish whereas in the Patagonian squid cadmium (Cd) was the heavy metal with the highest concentration, with the order of other metals being Cd > Hg > Pb. The heavy metal concentrations have been used to address the health risks using the Estimated Weekly Intake (EWI), Target Hazard Quotients (THQ), and Hazard Indices (HI). The findings revealed that the concentrations of the tested heavy metals, expressed on a per wet weight basis, did not exceed the Maximum Residue Levels (MRL) for those compounds mandated by national Croatian legislation. However, the HI for Hg was above 1, indicating a risk of adverse health effects due to the presence of this heavy metal in the consumed seafood. We conclude that the consumption of certain type of seafood such as the tuna fish should be limited when sensitive segments of the population such as children, elderly and pregnant women are concerned. Our results strongly advocate for a more stringent seafood quality control in the region.

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Assessment of renal and hepatic dysfunction by co-exposure to toxic metals (Cd, Pb) and fluoride in people living nearby an industrial zone

Cited by 18 publications

References 37 publications

Chemical Contamination in Bread from Food Processing and Its Environmental Origin

Chemical Contamination in Bread from Food Processing and Its Environmental Origin

Agricultural Strategies to Reduce Cadmium Accumulation in Crops for Food Safety

Assessment of health risks associated with heavy metal concentration in seafood from North-Western Croatia

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