The Ukrainian part of the sub-basin of Tisza, the largest left tributary of the Danube, which is located within five countries (Romania, Hungary, Slovakia, Ukraine, Serbia), is considered. This area due to the interaction of a number of natural and man-made factors is characterized by high risk of natural phenomena occurrence, particularly, floods, mudflows and landslides. There is a negative tendency in Ukraine to reduce the hydrogeological observation network. Obviously, that for the study area, further development of the monitoring system (restoration of stopped wells and construction of new wells) is expedient. In a geoinformation environment, a single monitoring geodatabase was created, that allowed maximum consideration of the results of hydrogeological surveys, ensured integration heterogeneous data and their overlay analysis, provided opportunities for effective design and optimization of the observation network based on the hydrogeological, analytical and statistical criteria.