Assessment of myocardial ischemia by strain dobutamine stress echocardiography and cardiac magnetic resonance perfusion imaging before and after coronary artery bypass grafting

Nuclear Medicine Communications

et al. 2022

Purpose: To evaluate the effects of ltered back projection (FBP), ordered subset expectation maximisation (OSEM), and different lters on cadmium zinc telluride single photon emission computed tomography (CZT SPECT) cerebral blood perfusion image quality to optimise the image reconstruction method.Methods: Jaszczak phantom and patients with clinical cerebral ischemia were selected as study subjects. Under routine clinical conditions, tomographic imaging was performed on the phantom and patients with clinical cerebral ischemia. Image processing included image reconstruction using ltered back projection with Chang's attenuation correction (FBP ChangAC ) and OSEM algorithm with CT-based attenuation correction (CTAC), scatter correction (SC), resolution recovery (RR) (OSEM CTAC-SC-RR ), and the ltering method used Butterworth (Bw) and Gauss (Gs) lters. Visual and semi-quantitative parameters (integral uniformity, root mean square noise (RMS noise), and contrast and contrast-to-noise ratio (CNR)) were used to evaluate image quality to optimise image reconstruction parameters. One-way and two-way ANOVA were used to process phantom and clinical data.Results: In the tomographic images of phantom and brain imaging of patients, FBP+Bw had the best uniformity and the lowest noise level, while OSEM+Bw had the best contrast. Semi-quantitative analysis showed that the integral uniformity of FBP+Bw was signi cantly higher than that of OSEM+Bw and OSEM+Gs (p <0.05), and that the RMS noise of FBP+Bw was signi cantly lower than that of OSEM+Bw and OSEM+Gs (p <0.001). The contrast of FBP+Bw and OSEM+Bw in the cold sphere diameter ≥ 2 cm group was signi cantly higher than that of OSEM+Gs (p <0.001), while the CNR of FBP+Bw was signi cantly higher than that of OSEM+Bw and OSEM+Gs (p <0.001) ; the contrast of OSEM+Bw cold sphere diameter < 2 cm was signi cantly higher than that of FBP+Bw (p <0.01). The semi-quantitative analysis results of the patient's cerebral perfusion tomography were consistent with the model. Conclusion:In CZT SPECT cerebral blood ow perfusion imaging, images with lesion sizes greater than 2 cm were suitable for FBP+Bw (fc=0.40, n=10), and the image with lesion size less than 2 cm was suitable for OSEM+Bw (EM=60, fc=0.45, n=10). The reconstruction method of OSEM+Gs (EM=80, full width at half maximum [FWHM]=3.25) was not suitable for cerebral blood perfusion imaging.

Section: Uniformity and Noisementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optimization of image reconstruction method of cerebral blood flow perfusion imaging with digital CZT SPECT

Zhou

Nuclear Medicine Communications

et al. 2022

“…Five 15×15-pixel square regions of interest (ROIs) were drawn at different positions on the transverse of the uniform part of the phantom to record the average, maximum, minimum, and standard deviation of the radioactivity count in each ROI, and the formula calculation was carried out after taking the average of each value, such as formulas ( 1) and (2).…”

Section: Uniformity and Noisementioning

confidence: 99%

“…With an increasing aging population, the incidence of this disease has been increasing year by year, and it has become a public health concern threatening human health. Cerebral blood perfusion imaging can be used to assess the local cerebral blood ow and cerebrovascular reserve at rest, and it has unique advantages in lesion guidance; prognostic evaluation of many diseases such as cerebral infarction, transient ischemic attack (TIA), epilepsy, and other ischemic lesions; and normal brain function research [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

Optimization of Image Reconstruction Method of Cerebral Blood Flow Perfusion Imaging with Digital CZT SPECT

Zhou

et al. 2021

Preprint

Purpose: To evaluate the effects of filtered back projection (FBP), ordered subset expectation maximisation (OSEM), and different filters on cadmium zinc telluride single photon emission computed tomography (CZT SPECT) cerebral blood perfusion image quality to optimise the image reconstruction method.Methods: Jaszczak phantom and patients with clinical cerebral ischemia were selected as study subjects. Under routine clinical conditions, tomographic imaging was performed on the phantom and patients with clinical cerebral ischemia. Image processing included image reconstruction using filtered back projection with Chang’s attenuation correction (FBPChangAC) and OSEM algorithm with CT-based attenuation correction (CTAC), scatter correction (SC), resolution recovery (RR) (OSEMCTAC-SC-RR), and the filtering method used Butterworth (Bw) and Gauss (Gs) filters. Visual and semi-quantitative parameters (integral uniformity, root mean square noise (RMS noise), and contrast and contrast-to-noise ratio (CNR)) were used to evaluate image quality to optimise image reconstruction parameters. One-way and two-way ANOVA were used to process phantom and clinical data.Results: In the tomographic images of phantom and brain imaging of patients, FBP+Bw had the best uniformity and the lowest noise level, while OSEM+Bw had the best contrast. Semi-quantitative analysis showed that the integral uniformity of FBP+Bw was significantly higher than that of OSEM+Bw and OSEM+Gs (p <0.05), and that the RMS noise of FBP+Bw was significantly lower than that of OSEM+Bw and OSEM+Gs (p <0.001). The contrast of FBP+Bw and OSEM+Bw in the cold sphere diameter ≥ 2 cm group was significantly higher than that of OSEM+Gs (p <0.001), while the CNR of FBP+Bw was significantly higher than that of OSEM+Bw and OSEM+Gs (p <0.001) ; the contrast of OSEM+Bw cold sphere diameter < 2 cm was significantly higher than that of FBP+Bw (p <0.01). The semi-quantitative analysis results of the patient's cerebral perfusion tomography were consistent with the model.Conclusion: In CZT SPECT cerebral blood flow perfusion imaging, images with lesion sizes greater than 2 cm were suitable for FBP+Bw (fc=0.40, n=10), and the image with lesion size less than 2 cm was suitable for OSEM+Bw (EM=60, fc=0.45, n=10). The reconstruction method of OSEM+Gs (EM=80, full width at half maximum [FWHM]=3.25) was not suitable for cerebral blood perfusion imaging.

“…1,2 Approximately one million OPCAB procedures are performed worldwide each year because coronary revascularization can improve myocardial ischemia, further ameliorate cardiac function and reduce the risk of sudden cardiac death, thereby, greatly improving quality of life and prolonging the lives of patients. 3,4 Several researchers have studied the improvements in myocardial ischemia after surgery from different viewpoints, including changes in myocardial nuclides, 5 echocardiography 6 and electrocardiograms. 7 However, the specific mechanism is still not clear.…”

Section: Introductionmentioning

confidence: 99%

Observation of local cardiac electrophysiological changes during off-pump coronary artery bypass grafting using epicardial mapping

Qin

et al. 2018

Perfusion