Assessment of mutagenicity of water from Lake Sevan, Armenia with application of Tradescantia (clone 02)

Avalyan, R.E.; Aghajanyan, Evelina; Khosrovyan, Alla; Atoyants, Anahit; Simonyan, Anna; Aroutiounian, Rouben

doi:10.1016/j.mrfmmm.2017.03.006

Cited by 12 publications

(2 citation statements)

References 14 publications

(17 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More recently, there is a growing interest in examining the cytotoxic potential of water as a more comprehensive approach to water quality assessment. In a recent study, water samples collected from Lake Sevans in Armenia showed a mutagenic activity when tested in vitro [ 3 ]. Similar results were reported for drinking water obtained from six different locations in China, also demonstrating a mutagenic potential and DNA damaging activity in vitro [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity of water supply in a Palestinian refugee camp and a Syrian informal tented settlement in Lebanon

El Kawak,

Al Hassanieh,

Berjawi

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Deficient water, sanitation, and hygiene (WASH) significantly account for a high burden of disease across the globe. Lebanon, an Eastern Mediterranean lower-middle-income country with a polluted environment, a fragmented healthcare system, and an ongoing severe economic crisis, faces serious challenges in sustaining safe water supplies, especially in vulnerable communities, while also hosting the world highest refugee population per capita. This study aimed to examine the mutagenicity, and the estrogenic and androgenic activities of water supplies, across both a Palestinian refugee camp and a Syrian informal settlement. Water samples were collected from two targeted camps in Dbayeh and Choueifat, North and South of the Capital City Beirut, respectively, between the months of September and October 2022. Microbial and physicochemical properties of samples were determined, including fecal contamination, total dissolved solids, and various minerals and salts. Organic pollutants were extracted using pre-packed solid phase extraction (SPE) columns, and then mutagenicity of extracts was examined using the Ames test in two Salmonella typhi bacterial strains. The estrogenic and androgenic activities of extracts were assessed using the yeast estrogen and androgen screen tests assays (YES/YAS). Results show excessive levels of total coliforms and total dissolved solids (TDS) in samples from both sites. In addition, the water supply from the Dbayeh Palestinian refugee camp is mutagenic, while the water supply from the Choueifat Syrian informal settlement shows anti-androgen activity. Our findings provide valuable WASH baseline data in two major vulnerable communities in Lebanon, and highlight the importance of a water toxicity testing approach concomitant with a water safety plan, based on a holistic strategy that covers all stages of the water supply chain.

show abstract

Section: Introductionmentioning

confidence: 99%

Cytotoxicity of water supply in a Palestinian refugee camp and a Syrian informal tented settlement in Lebanon

El Kawak,

Al Hassanieh,

Berjawi

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Having such economic and strategic importance, Lake Sevan has been affected by various anthropogenic factors. Sevan basin drains 28 tributaries that flow through urban, agricultural, and industrial areas and transfer industrial, agricultural, and domestic waste into the lake causing changes in the lake ecosystem (Hovhannissian, 1994;Avalyan et al, 2017). Hence, the Lake Sevan catchment basin management has always been an important environmental issue for investigators and decision-makers.…”

Section: Introductionmentioning

confidence: 99%

Lake-wide assessment of trace elements in surface sediments and water of Lake Sevan

et al. 2023

View full text Add to dashboard Cite

Lake Sevan (Armenia) is one of the large freshwater high-mountain lakes of Eurasia. Detailed information about the extent and fate of trace elements on lake sediment and water quality has not been published yet. For this reason, surface sediment and water samples were collected from the southern and northern basins of Lake Sevan to determine trace element concentrations and assess the trace element behaviour. Geo-accumulation index, potential ecological risk index, and hazard index were calculated to estimate the environmental risk potential. In comparison to reference values, the investigated sediment samples contained elevated concentrations frequently for V, Cr, Co, Ni, Mo, Cd, Be, Ti, Rb, Sr, Se, Hf, and Th and occasionally for Cu, As, Li, B, Ag, Sb, Tl, Bi, U, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, and Tm. An overall potential ecological risk posed by all the investigated trace elements in the sediments was assessed to be moderate-considerable, however, Mo, Hg, and Cd were the elements with the highest ecological risk potential. The two basins of the lake showed significantly different behaviour according to the investigated trace element contents in the sediments to be higher in the bigger basin compared to the smaller basin. In comparison to reference concentrations in water samples according to the use of the adapted geo-accumulation index, elevated values for Ti, Cr, Cu, Cd, and Pb were observed. Elevated concentration was also observed in the case of B in nearly all water samples in comparison with literature values. Nevertheless, several water samples can be seen as not strongly anthropogenic influenced by Co, Ni, Sn, Sb, Ag, Hg, and Bi. The concentrations of trace elements in the lake water caused health risks to humans particularly children in the case of lake water used for drinking purposes, moreover, As was the main element posing health hazards. The results point out further attention to the sources of elevated trace elements in Lake Sevan, including anthropogenic influences and geological characteristics.

show abstract

A Novel Approach to Monitoring the Quality of Lakes Water by Optical and Modeling Tools: Lake Sevan as a Case Study

Varotsos

Krapivin

Mkrtchyan

et al. 2020

Water Air Soil Pollut

View full text Add to dashboard Cite

Assessment of mutagenicity of water from Lake Sevan, Armenia with application of Tradescantia (clone 02)

Cited by 12 publications

References 14 publications

Cytotoxicity of water supply in a Palestinian refugee camp and a Syrian informal tented settlement in Lebanon

Cytotoxicity of water supply in a Palestinian refugee camp and a Syrian informal tented settlement in Lebanon

Lake-wide assessment of trace elements in surface sediments and water of Lake Sevan

A Novel Approach to Monitoring the Quality of Lakes Water by Optical and Modeling Tools: Lake Sevan as a Case Study

Contact Info

Product

Resources

About