Assessment of medication adherence among hypertensive patients: a cross-sectional study

Bhusal, Anup; Jadhav, Pradeep R.; Deshmukh, Y. A.

doi:10.18203/2319-2003.ijbcp20162480

Cited by 7 publications

(7 citation statements)

References 31 publications

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“…The major finding of this study revealed that about two-thirds of the hypertensive patients on antihypertensive treatment had controlled BP. The level of BP control found in this study (63.6%) was relatively comparable with studies from health care in Chilean (59.7%), 39 in USA at different levels of the health system (60%), 40 South Africa (57%), 41 Bhusal et al in India (58.9%), 5 by Sandoval et al in Chile (63.1%) 27 and by Cordero et al in Spain (55.4%). 10 This close similarity in the level of BP control might be due to similarities in the eligibility criteria for the studies as only hypertensive patients on pharmacologic therapy were included.…”

Section: Discussionsupporting

confidence: 86%

“…[1][2][3][4] It is usually asymptomatic and chronic disorder needing lifelong treatment. 5,6 HTN affects around one billion individuals globally and the burden is projected to increase by 29% to reach 1.56 billion by 2025. 1,[5][6][7][8] It is one of the major, prevalent but modifiable risk factors, especially among patients with established cardiovascular disease (CVD) and cerebrovascular accidents.…”

Section: Introductionmentioning

confidence: 99%

“…5,6 HTN affects around one billion individuals globally and the burden is projected to increase by 29% to reach 1.56 billion by 2025. 1,[5][6][7][8] It is one of the major, prevalent but modifiable risk factors, especially among patients with established cardiovascular disease (CVD) and cerebrovascular accidents. 2,9,10 As a result, HTN is the leading cause of morbidity and mortality among non-communicable diseases [11][12][13][14][15] and ranks third as a cause of disability-adjusted life-year causing about 7.1 million premature deaths each year.…”

Section: Introductionmentioning

confidence: 99%

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<p>Magnitude and Determinants of Uncontrolled Blood Pressure Among Adult Hypertensive Patients on Follow-Up at Nekemte Referral Hospital, Western Ethiopia</p>

Fekadu¹,

Adamu²,

Gebre³

et al. 2020

IBPC

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Background: Hypertension is the leading cause of morbidity and mortality among noncommunicable diseases. The rate of blood pressure (BP) control among hypertensive patients is poor and the reasons for poor control of BP remain poorly understood globally. Therefore, this study aimed to assess the magnitude and determinants of uncontrolled blood pressure among adult hypertensive patients on follow-up at Nekemte referral hospital (NRH). Methods: A hospital-based cross-sectional study was conducted from February to April 2018 at NRH. BP control status was determined by the average consecutive BP recordings across the 3 months. The data was entered and analyzed using SPSS version 20.0 and p-value <0.05 was considered statistically significant. Results: Out of 297 study participants included, the majority were females, 181 (60.9%), and the mean age of the patients was 59.4 ±10.4 years. About half, 137 (46.12%), of the patients had at least one comorbidity and the most common class of anti-hypertensive medication was angiotensin-converting enzyme inhibitors (88.2%). The mean of systolic blood pressure was 132.41± 15.61mmHg, while the mean of diastolic blood pressure was 84.37± 9.32 mmHg. The proportion of participants with optimally controlled BP was 63.6% and 36% were adherent to their medications. Male sex (Adjusted Odd Ratio [AOR]: 1.89, 95% CI: 1.09-4.84), illiteracy (AOR= 1.56, 95% CI: 1.22-6.78), duration of hypertension diagnosis > 10 years (AOR= 2.01, 95% CI: 1.04-16.11), non-adherence (AOR= 3.14, 95% CI: 1.35-10.76) and lack of physical exercise (AOR= 2.8, 95% CI: 1.16-6.74) were positively associated with uncontrolled BP status. Whereas age older than 55 years (AOR= 0.38, 95% CI: 0.11-0.92) was negatively associated with uncontrolled BP. Conclusion: BP control was relatively achieved in about two-third of pharmacologically treated patients. We recommend better health education and care of patients to improve the rate of BP control status.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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<p>Magnitude and Determinants of Uncontrolled Blood Pressure Among Adult Hypertensive Patients on Follow-Up at Nekemte Referral Hospital, Western Ethiopia</p>

Fekadu¹,

Adamu²,

Gebre³

et al. 2020

IBPC

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“…These were the existing factors expected to be influential the adherence to anti-hypertensive medication, (Table 3) shows that, some patients respond to more than one factor so that the value seems to be more than the total nonadherence value. 7,[11][12][13][14][15][16] Higher non-adherence in above mentioned studied observed might be due to use difference methods or tools to measure treatment adherence of hypertension.…”

Section: Treatmentmentioning

confidence: 99%

Antihypertension medication adherence and associated factors at tertiary care hospital, Gujarat, India

Goswami

2019

Int J Adv Med

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Background: According to world health organization (WHO) describes poor adherence as the identical cause of uncontrolled blood pressure and estimates that 50-70% of people do not take their antihypertensive medication as prescribed. The objectives of this study were to investigate the adherence and persistence of antihypertensive drugs in Indian rural population as well as monitoring adverse drug reactions and its relation to compliance.Methods: This cross-sectional study conducted among 300 hypertensive patients taking treatment at tertiary care hospital in Gujarat, India. Structured questionnaires consisting of open and closed ended questions on the antihypertensive drug adherence were distributed to patients for those found on the study area at time of data collection and the left-over pills of individual patient were counted to strengthen the consistency of the research.Results: Prevalence of non-adherence found in 24.3% participants. Present study found statistically significant association between socio-demographic factors (age, religion, marital status, occupation, substance abuse, education and family history of HT) with treatment adherence of hypertension among study participants. The other factor associated to non-adherence was therapy factor 32.9% (P=0.001) from the total non-adherence, in this case patients were supposed to unwanted effect of the drug and they were not able to take the medication.Conclusions: The main possible reasons for non-adherence were ‘refuse to take regular treatment’,‘cost of treatment’, ‘poor patient-doctor relation’, ‘unwanted side effect of drugs’ and other factors like age, marital status, occupation, education level, family H/O, substance abuse and religion are also playing supporting role to develop non-adherence to treatment.

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“…The overall prevalence is around 29.6% with regional variation in rural (27.6%) and urban (33.8%) population. 2 In conjunction with primary casual factor a number of adjunctive factors such as, emotional stress, sedentary life style and low potassium intake may increase the probability of developing HTN, hence on a similar dietary salt, some individuals develop HTN while others do not and the probability to develop hypertension depends on the individuals weight of hypertensions adjunctive factors. 3 Hypertension treatment starts with therapeutic lifestyle changes for all individuals with hypertension and prehypertension.…”

Section: Introductionmentioning

confidence: 99%

A Study to Evaluate Pharmacoeconomics of Antihypertensive Drugs in a Tertiary Care Teaching Hospital

John¹,

Krishnan²,

Midhun³

et al. 2020

J. Drug Delivery Ther.

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Background: Hypertension is a major public health problem associated with large health burden as well as high economic burden at individual and population levels. A prospective observational study carried out in in-patients admitted to general medicine department of tertiary care hospital to evaluate the most cost effective therapy among the monotherapy of Amlodipine and combination therapy of telmisartan + hydrochlorthiazide. Methods: A total of 120 Hypertensive patients case records prescribed with monotherapy of Amlodipine and combination therapy of Telma H were reviewed and evaluated using descriptive statistics and ‘p’ value and assessed for their financial burden based on the cost per tablet for an year, Cost effectiveness ratio for the patients with controlled Blood Pressure by using a particular drug. Results: Out of 120 patients females were more (59.2%) and most of them were under the age group of 41-60 years. Majority of the patients had a known history of hypertension (65%). Most of the patients were prescribed with Telma H 40/12.5mg (40%) followed with Amlong 5mg (35.8%). There was a significant positive correlation (i.e., p value= 0.05) between persistence patterns of patients with drug therapy. Probability of patients with controlled Blood Pressure taking Amlong 10 mg were 82.35% followed by patients with Amlong 5mg. Conclusion: This study clearly showed that monotherapy of amlodipine is the most cost effective therapy than combination therapy of Telma H in order to reduce financial burden to the patient as well as to decrease the complications. Keywords: Hypertension, Pharmacoeconomics, Cost effectiveness, Blood Pressure.

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Assessment of medication adherence among hypertensive patients: a cross-sectional study

Cited by 7 publications

References 31 publications

<p>Magnitude and Determinants of Uncontrolled Blood Pressure Among Adult Hypertensive Patients on Follow-Up at Nekemte Referral Hospital, Western Ethiopia</p>

<p>Magnitude and Determinants of Uncontrolled Blood Pressure Among Adult Hypertensive Patients on Follow-Up at Nekemte Referral Hospital, Western Ethiopia</p>

Antihypertension medication adherence and associated factors at tertiary care hospital, Gujarat, India

A Study to Evaluate Pharmacoeconomics of Antihypertensive Drugs in a Tertiary Care Teaching Hospital

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