“…34 The superiority of 3D STE over 2D STE for the evaluation of all three components of LV deformation (GLS, GCS, and GRS) has been questioned. 35 The 3D mode has good reproducibility as an automated method, as shown by the lower intraobserver and interobserver variability, it avoids foreshortening of apical views, it consumes less time in data acquisition, and an helps solve the problem of out-of-plane motion present in the 2D modality, tracking the motion of speckles in all three dimensions. However, this advantage is achieved at the expense of a lower volume rate, which might alter the correlations with measurements obtained by 2D STE.…”