Assessment of knee extensor and flexor function using isokinetic test in COPD: impact on exercise capacity

Li, P; Wang, Z; Lu, Yue; Li, N; Xiao, Lianbo; Su, Jianqing; Duan, Hongxia; Liu, X; Wu, Wenqing

doi:10.5588/ijtld.19.0588

Cited by 3 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The existence of dyspnea in COPD decreases physical activity, and the decrease in physical activity induces and accelerates skeletal muscle dysfunction, worsening the dyspnea in patients, forming a vicious cycle that causes further deconditioning on COPD ( 7 ). Recently, lower limb muscle function has been associated with exercise capacity in COPD ( 8 ). Previous studies have confirmed that skeletal muscle dysfunction is an additional important contributor to COPD exercise restriction and function impairments ( 9 , 10 ), and it is closely related to the quality of life, readmission rate, and mortality ( 11 , 12 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of Exercise Intervention on Peripheral Skeletal Muscle in Stable Patients With COPD: A Systematic Review and Meta-Analysis

Wang

et al. 2021

Front. Med.

View full text Add to dashboard Cite

Objectives: Peripheral skeletal muscle dysfunction is an important extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD) that can be counteracted by exercise training. This study aimed to review the effect of three major exercise training modalities, which are used in pulmonary rehabilitation to improve on skeletal muscle mass, function, and exercise capacity in COPD.Methods: PubMed, Embase, EBSCO, Web of Science, and the PEDro database were searched on April 25, 2020. Only randomized controlled studies published in English evaluating the effects of exercise interventions on peripheral skeletal muscle mass, strength, and exercise capacity in stable COPD patients were included. The quality of included studies was evaluated using the PEDro scale. The mean difference (MD) or the standardized mean difference (SMD) with 95% CI was calculated to summarize the results. Subgroup meta-analysis was used to investigate the effects of different exercise training modalities and different outcome measures. The Grading of Recommendations Assessment, Development, and Evaluation guidelines were used to rate evidence quality.Results: A total of 30 randomized controlled trials involving 1,317 participants were included. Data from trials investigating endurance exercise (EE), resistance exercise (RE), and combined aerobic and resistance exercise (CE) were pooled into a meta-analysis, and the differences compared with the non-exercising COPD control were improvement in the muscle strength and exercise capacity in stable COPD patients. Subgroup meta-analysis for different exercise training modalities showed that RE significantly improved muscle strength (SMD = 0.6, 95% CI 0.35–0.84, I2 = 61%), EE and CE significantly increased VO2peak (EE: MD = 3.5, 95% CI 1.1–5.91, I2 = 92%; CE: MD = 1.66, 95% CI 0.22–3.1, I2 = 1%). Subgroup meta-analysis for different outcome measures showed that only isotonic strength was improved after exercise interventions (SMD = 0.89, 95% CI 0.51–1.26, I2 = 71%).Conclusion: Moderate evidence supports that exercise training in stable COPD patients has meaningful and beneficial effects on peripheral skeletal muscle strength and exercise capacity. Peripheral skeletal muscle shows a higher response to RE, and the isotonic test is relatively sensitive in reflecting muscle strength changes. The proportion of aerobic and resistance exercise components in a combined exercise program still needs exploration.Systematic Review Registration: The review was registered with the PROSPERO: (The website is https://www.crd.york.ac.uk/PROSPERO/, and the ID is CRD42020164868).

show abstract

Section: Introductionmentioning

confidence: 99%

Effects of Exercise Intervention on Peripheral Skeletal Muscle in Stable Patients With COPD: A Systematic Review and Meta-Analysis

Wang

et al. 2021

Front. Med.

View full text Add to dashboard Cite

show abstract

The effects of a physical exercise program in Chinese kidney transplant recipients: a prospective randomised controlled trial

Zhang

Liu

Zhu

et al. 2023

Clinical Kidney Journal

View full text Add to dashboard Cite

Background Kidney transplant has become the preferred therapy for end-stage renal disease. However, kidney transplant recipients still face several challenges, such as physical inactivity. The purpose of this study was to explore the effects of a nurse-led physical exercise programme in Chinese kidney transplant recipients. Methods One hundred and six participants were enrolled from the Third Xiangya Hospital of Central South University between July 2021 and June 2022 and randomly assigned to the control or intervention groups. Participants in the control group were provided with routine nursing care, and participants in the intervention group received nurse-led rigorous physical exercise programme, which was divided into two stages: the pre-discharge stage and the post-discharge stage. The pre-discharge stage included the non-ambulatory and ambulatory stages. The Chinese traditional exercise- Badunjin was incorporated into the physical exercise during the ambulatory stage. The post-discharge stage continued the same exercise as the ambulatory stage at home. After 3 months of intervention, both groups received the same follow-up for 3 months. The primary and secondary outcomes of all participants were collected. The data was analysed with repeated-measure ANOVA to examine the effectiveness of the intervention. Results Compared to the control group, the intervention group had less fatigue and more motivation to be active in primary outcomes. Moreover, patients in the intervention group had a higher phase angle, a longer 6-minute walk distance, more 30-second chair stand times, and decreased anxiety and depression level in secondary outcomes. No adverse events were observed during the intervention. There were no significant differences in all dimensions of the quality of life questionnaire between the intervention and the control group. Conclusion Chinese kidney transplant recipients could benefit from the nurse-led physical exercise programme post-operatively. Trial Registration: ChiCTR2100048755

show abstract

Table_1.docx

View full text Add to dashboard Cite

Assessment of knee extensor and flexor function using isokinetic test in COPD: impact on exercise capacity

Cited by 3 publications

References 0 publications

Effects of Exercise Intervention on Peripheral Skeletal Muscle in Stable Patients With COPD: A Systematic Review and Meta-Analysis

Effects of Exercise Intervention on Peripheral Skeletal Muscle in Stable Patients With COPD: A Systematic Review and Meta-Analysis

The effects of a physical exercise program in Chinese kidney transplant recipients: a prospective randomised controlled trial

Table_1.docx

Contact Info

Product

Resources

About