Abstract:Background: Pediatric-onset systemic lupus erythematosus (pSLE) is an autoimmune disease with multiorgan involvement and accounts for 15% to 20% of all systemic lupus erythematosus (SLE) cases. Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease characterized by variable immune dysregulation, disabling symptoms, and progressive organ damage. Interleukin (IL) -34 is a newly discovered cytokine that has no significant amino acid sequence homology to other cytokines. Objective: This study ai… Show more
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