Assessment of image quality and low-contrast detectability in abdominal CT of obese patients: comparison of a novel integrated circuit with a conventional discrete circuit detector at different tube voltages

Euler, André; Heye, Tobias; Kekelidze, Maka; Bongartz, Georg; Szücs-Farkas, Zsolt; Sommer, Christof M.; Schmidt, Bernhard; Schindera, Sebastian T.

doi:10.1007/s00330-014-3459-4

Cited by 5 publications

(4 citation statements)

References 22 publications

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“…This results in a higher image quality and a reduction of radiation dose for low tube current protocols because less photons are traversing the patient. 3,15 In our study, image noise was significantly reduced up to 71.6% in images obtained with 1/8 of the standard dose using ADMIRE 5 compared with FBP and led to an improvement of the subjective image quality.…”

Section: Discussionsupporting

confidence: 50%

“…Subsequently, statistical optimization of the data is performed, reaching a target noise reduction which depends on the selected ADMIRE strength level. 15,16 Compared with the antecessor SAFIRE (sinogram affirmed iterative reconstruction), ADMIRE offers a higher resolution at organ borders, improving delineation of edges and thus is beneficial also for pulmonary nodule detection. 15 Subsequent analyses were performed using a picture archiving and communication system (Impax, V. 6.5.5.1033; Agfa-Gevaert, Mortsel, Belgium) on a high-definition liquid crystal display monitor (Barco™; Medical Imaging Systems, Kortrijk, Belgium).…”

Section: Data Reconstructionmentioning

confidence: 99%

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Ultralow-dose CT with tin filtration for detection of solid and sub solid pulmonary nodules: a phantom study

Martini

Higashigaito

Barth

et al. 2015

BJR

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Objectives: To investigate the diagnostic performance of advanced modelled iterative reconstruction (ADMIRE) to filtered back projection (FBP) when using an ultralow-dose protocol for the detection of solid and subsolid pulmonary nodules. Methods: Single-energy CT was performed at 100 kVp with tin filtration in an anthropomorphic chest phantom with solid and subsolid pulmonary nodules (2-10 mm, attenuation, 20 to 2800 HU at 120 kVp). The mean volume CT dose index (CTDI vol ) of the standard chest protocol was 2.2 mGy. Subsequent scans were obtained at 1/8 (0.28 mGy), 1/20 (0.10 mGy) and 1/70 (0.03 mGy) dose levels by lowering tube voltage and tube current. Images were reconstructed with FBP and ADMIRE. One reader measured image noise; two readers determined image quality and assessed nodule localization.Results: Image noise was significantly reduced using ADMIRE compared with FBP (ADMIRE at a strength level of 5 : 70.4% for 1/20; 71.6% for 1/8; p , 0.001). Interobserver agreement for image quality was excellent (k 5 0.88). Image quality was considered diagnostic for all images at 1/20 dose using ADMIRE. Sensitivity of nodule detection was 97.1% (100% for solid, 93.8% for subsolid nodules) at 1/20 dose and 100% for both nodule entities at 1/8 dose using ADMIRE 5. Images obtained with 1/70 dose had moderate sensitivity (overall 85.7%; solid 95%; subsolid 73.3%). Conclusion: Our study suggests that with a combination of tin filtration and ADMIRE, the CTDI vol of chest CT can be lowered considerably, while sensitivity for nodule detection remains high. For solid nodules, CTDI vol was 0.10 mGy, while subsolid nodules required a slightly higher CTDI vol of 0.28 mGy. Advances in knowledge: Detection of subsolid nodules is feasible with ultralow-dose protocols.

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Section: Discussionsupporting

confidence: 50%

Section: Data Reconstructionmentioning

confidence: 99%

Ultralow-dose CT with tin filtration for detection of solid and sub solid pulmonary nodules: a phantom study

Martini

Higashigaito

Barth

et al. 2015

BJR

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“…Although technical improvements like integrated circuit detectors and iterative reconstructions have led to an improved image quality in CT while radiation dose could be markedly reduced, artifacts due to implanted metal-containing materials such as endoprostheses and coils are an enduring challenge in CT examinations and can hamper clinical diagnosis (1)(2)(3). Besides image interpretation, artifacts from high-density objects represent a severe problem for radiation therapy planning and attenuation correction in positron emission tomography CT (PET-CT) (4)(5)(6)(7).…”

Section: Introductionmentioning

confidence: 99%

Metal artifact reduction (MAR) based on two-compartment physical modeling: evaluation in patients with hip implants

et al. 2016

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“…The purified energy spectrum improves material resolution, and a larger pitch (2.0) can be selected, which is more effective in reducing radiation dose. Euler et al [17] used a Stellar photon detector with reduced electronic noise and an iterative reconstruction algorithm and found that this method not only reduced the radiation dose for chest examination by 45.6% but it also improved the signal-to-noise ratio and contrast noise ratio of the image. In this study, image noise and the contrast nose ratio from the Sn100-LDCT scan were significantly higher than from the ECG-CT scan, but the calcified branches of the coronary arteries in the ECG-CT scan were all shown in the Sn100-LDCT scan, and the coronary artery calcification score was calculated without omission.…”

Section: Discussionmentioning

confidence: 99%

Accuracy of non-gated low-dose non-contrast chest CT with tin filtration for coronary artery calcium scoring

Liu¹,

Chen²,

Liu³

et al. 2022

European Journal of Radiology Open

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The study investigated the accuracy of coronary artery calcium scores (CACS) and the potential for reducing radiation dose using non-gated low-dose non-contrast chest computed tomography (CT) scanning with tin filtration for one-stop screening of the lungs and heart. Methods: A prospective study was conducted,193 Patients received two scans for determining CACS, including an ECG-gated CT at 120 kV (ECG-gated CT), followed by a non-gated low-dose chest CT using 100 kV with tin filtration (non-gated Sn100 kV-LDCT). The Agatston score (AS), risk stratification, and radiation dose were compared between the scan types. Results: There was good consistency in the AS from both an ECG-gated CT and a non-gated low-dose chest CT scan, which had a high correlation (r = 0.970). The Kappa value of risk stratification of the two scan types was 0.549. The area under the ROC curve (AUC) of the CACS was used to develop a new risk stratification standard for non-gated Sn100 kV-LDCT evaluation of CACS. In comparison to the CACS measured by ECG-gated CT, nongated Sn100 kV-LDCT had an AUC of 0.951 and an optimal critical value of 4.6 in the low-risk category. The AUC of low-medium risk was 0.966, and the optimal critical value was 41.2. The AUC of the medium-high risk category was 0.968, and the optimal critical value was 230. The consistency in CACS measured by ECG-gated CT and non-gated Sn100 kV-LDCT had a Kappa value of 0.831. The Effective dose (ED) of non-gated Sn100 kV-LDCT and ECG-gated CT was 0.056 ± 0.017 mSv and 0.685 ± 0.455 mSv, respectively (p < 0.05). Conclusion:The Agatston score of CACS using non-gated low-dose chest CT was accurate, but there was an underestimation in risk stratification. This study developed a new risk stratification standard for non-gated Sn100 kV-LDCT evaluation of CACS, which is in closer agreement with CACS derived from ECG-gated CT scans.

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Assessment of image quality and low-contrast detectability in abdominal CT of obese patients: comparison of a novel integrated circuit with a conventional discrete circuit detector at different tube voltages

Abstract: The IC detector at 100 kVp resulted in similar low-contrast detectability compared to the conventional detector with a 120-kVp protocol at a radiation dose reduction of 37 %.

Cited by 5 publications

References 22 publications

Ultralow-dose CT with tin filtration for detection of solid and sub solid pulmonary nodules: a phantom study

Ultralow-dose CT with tin filtration for detection of solid and sub solid pulmonary nodules: a phantom study

Metal artifact reduction (MAR) based on two-compartment physical modeling: evaluation in patients with hip implants

Accuracy of non-gated low-dose non-contrast chest CT with tin filtration for coronary artery calcium scoring

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