Assessment of HRQoL in patients with eating disorders by the beta‐binomial regression approach

Aróstegui, Inmaculada; Padierna, Ángel; Quintana, José M.

doi:10.1002/eat.20713

Cited by 7 publications

(6 citation statements)

References 47 publications

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“…Therefore, selecting an appropriate method of analysis of anxiety and depression scores is a challenge in itself. To date, BBR has proved useful in a series of biomedical applications, for example, in HRQoL in ED patients, in patients with chronic obstructive pulmonary disease and in lung cancer patients (Arostegui et al, ; Kahn et al, ; Najera‐Zuloaga et al, ). We have shown that HAD scores fit very well the beta‐binomial distribution, and therefore, the BBR is a natural approach for identifying factors that significantly affect anxiety and depression.…”

Section: Discussionmentioning

confidence: 99%

“…For this reason, parametric methods assuming normal distribution of the response variable are the most widely used statistical instruments in biomedicine (Ferrari & Cornelli, ). However, in psychological observational and experimental studies, patient‐reported outcomes (PROs)—such as health‐related quality of life (HRQoL) or symptomatology of anxiety and depression measures—are used as primary outcomes (Arostegui, Padierna, & Quintana, ; Testa & Simonson, ). These psychological parameters are continuous latent variables, although they are usually measured on an ordinal scale.…”

Section: Introductionmentioning

confidence: 99%

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Anxiety and depressive symptoms are related to core symptoms, general health outcome, and medical comorbidities in eating disorders

Martín

Aróstegui

Loroño

et al. 2019

Euro Eating Disorders Rev

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Objective The goal of this study is to identify potential factors that have a significant effect on anxiety and depression of patients with eating disorders (ED) using the beta‐binomial regression (BBR) approach on a broad sample of patients. Method This cross‐sectional study involved 520 ED patients. The effect of sociodemographics, core symptoms, general health outcomes, and medical comorbidities in anxiety and depression were analysed jointly using the beta‐binomial mixed‐effects model. Results Two hundred fifty‐five (49.4%) patients had anorexia nervosa, 173 (33.3%) patients had bulimia nervosa, and 92 (17.7%) had ED not otherwise specified. A high level of anxiety was associated, among other variables, with having a restrictive ED subtype as compared with purgative and binge ED subtypes (β = −0.2, p < 0.001, OR = 0.82 and β = −0.16, p < 0.03, OR = 0.85, respectively), with having a high level of ED symptomatology or with living not alone (β = −0.23, p = 0.002, OR = 0.80). A high level of depression was associated, among other variables, with older age (β = 0.74, p < 0.001, OR = 2.1). Conclusions The results of our study suggest that depressive and anxiety symptoms are related to ED symptoms, health status, ED subtype, medical comorbitidy, and educational level. In addition, another interesting finding is the inverse association between symptomatology of anxiety and living alone. Finally, BBR may be a useful approach in interpreting patient‐reported outcome as odds.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Anxiety and depressive symptoms are related to core symptoms, general health outcome, and medical comorbidities in eating disorders

Martín

Aróstegui

Loroño

et al. 2019

Euro Eating Disorders Rev

Self Cite

View full text Add to dashboard Cite

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“…One of these is that observed scores are discrete and bounded; the second is that observed scores may not be normally distributed and, even if they are, the measurement model does not ensure that observed scores on two actually parallel tests will have a bivariate normal distribution. These two characteristics are quite apparent in empirical distributions of observed test scores (see, e.g., Arostegui, Núñez-Antón, & Quintana, 2007;Arostegui, Padierna, & Quintana, 2010;Torrance et al, 2009) and pose a potential threat to the accuracy of statistical tests designed for use with continuous, unbounded, and normally distributed variables. This study used simulation methods to assess the accuracy (type I error rates) and power (one's complement of type II error rates) of each of the statistical tests described next.…”

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confidence: 99%

Statistical criteria for parallel tests: A comparison of accuracy and power

Garcı́a-Pérez

2013

Behav Res

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Parallel tests are needed so that alternate forms can be applied to different groups or on different occasions, but also in the context of split-half reliability estimation for a given test. Statistically, parallelism holds beyond reasonable doubt when the null hypotheses of equality of observed means and variances across the two forms (or halves) are not rejected. Several statistical tests have been proposed for this purpose, but their performance has never been compared. This study assessed the relative performance (type I error rate and power) of the Student-Pitman-Morgan, Bradley-Blackwood, and Wilks tests of equality of means and variances in the typical conditions surrounding studies of parallelism-namely, integer-valued and bounded test scores with distributions that may not be bivariate normal. The results advise against the use of the Wilks test and support the use of the Bradley-Blackwood test because of its simplicity and its minimally better performance in comparison with the more cumbersome Student-PitmanMorgan test.

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“…Transtornos Ansiosos mais comumente encontrados nos TA, e a prevalência que achamos, de 39,0%, está dentro da faixa de variação encontrada por Hudson et al, (2007) (Herzog et al, 1993;Fairburn et al, 2007;Turner et al, 2010) (Doll et al, 2005;Mond et al, 2005;De la Rie et al, 2005;Latner et al, 2008;Padierna et al, 2000;Gonzalez et al, 2001;Etxeberria et al, 2002;Scocco et al, 2006;Spitzer et al, 1995;Gonzalez-Pinto et al, 2004;Keillen, 1994;Herpertz-Dahlmann et al,2008;Jones et al, 2008;Arkell & Robinson, 2008;Muñoz et al, 2009;Bamford & Sly, 2010;Arostegui et al, 2010;Hay et al, 2010 (Keilen et al, 1994;Padierna et al, 2000;Turner et al, 2010), em particular do subtipo purgativo (Gonzalez-Pinto et al, 2004;Mond et al 2005;Ackard et al, 2011;Meguerditchian 2009). No entanto, tal diferença parece não se refletir regularmente nos estudos de QV, nos quais os dados que encontramos em revisão não foram conclusivos.…”

Section: Diferentes Estudos Têm Demonstrado O Surgimento De Transtornunclassified

“…Algumas investigações não constataram diferenças entre os subtipos de TA comparados (Gonzalez et al, 2001;De la Rie et al, 2005). Doll et al, (2005) (Danzl et al, 2001;Padierna et al, 2002;Padierna et al, 2004;Gonzalez et al, 2001;Munhõz et al, 2009;Bamford & Sly, 2010;Arostegui et al, 2010) Herpertz-Dahlmann et al,2008;Gonzalez-Pinto et al, 2004;Scocco et al, 2006), que evidenciaram deterioração global de QV, tanto nos domínios físico e psicológico como social, em pacientes adultos e adolescentes.…”

Section: Diferentes Estudos Têm Demonstrado O Surgimento De Transtornunclassified

Prejuízos da qualidade de vida em pacientes com transtornos alimentares

Taragano¹

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Taragano RO.Impairment of quality of life in patients with eating disorders.[Dissertação]. São Paulo: Universidade de São Paulo; 2013. Purpose: To assess quality of life in patients with eating disorders, verify differences among eating disorder subtypes, and identify the domains of quality of life most affected by eating disorders. Methods: The World Health Organization quality-of-life assessment instrument (WHOQOL-100) was completed by 69 women with eating disorders (34 with anorexia nervosa, 26 with bulimia nervosa, and 9 with eating disorder not otherwise specified) and 69 healthy women. The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) was used for the diagnosis of psychiatric disorders. Results: Patients with eating disorders reported lower (worse) total qualityof-life scores and lower scores on all quality-of-life domains (physical, psychological, social relationships, environment, level of independence, and spirituality) compared with healthy patients, with the psychological domain being the most impaired. No significant differences in impairment of quality of life were found among eating disorders subtypes. The most prevalent psychiatric comorbidities were mood disorders, alcohol or substance abuserelated disorders, and anxiety disorders. Patients with anorexia nervosa and comorbid panic disorder had greater impairment in quality of life than patients with anorexia nervosa but no panic disorder. Most patients had multiple comorbidities and history of suicide attempts. Conclusions: Patients with eating disorders experience significantly greater impairment in quality of life on all domains, especially on the psychological domain, compared with healthy patients, probably because of peculiarities in eating disorders psychopathology. No difference in quality of life impairment was observed among eating disorders subtypes. Patients with anorexia nervosa and comorbid panic disorder should be carefully evaluated.

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Assessment of HRQoL in patients with eating disorders by the beta‐binomial regression approach

Abstract: BBR models provide understandable results for clinicians and can be used in multivariate models with HRQoL dependent variables.

Cited by 7 publications

References 47 publications

Anxiety and depressive symptoms are related to core symptoms, general health outcome, and medical comorbidities in eating disorders

Anxiety and depressive symptoms are related to core symptoms, general health outcome, and medical comorbidities in eating disorders

Statistical criteria for parallel tests: A comparison of accuracy and power

Prejuízos da qualidade de vida em pacientes com transtornos alimentares

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