Assessment of Health-Related Quality of Life in Living Kidney Donors

Maglakelidze, N.; Pantsulaia, T.; Managadze, L.; Chkhotua, Archil

doi:10.1016/j.transproceed.2010.12.016

Cited by 21 publications

(10 citation statements)

References 13 publications

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“…In concurrence with our results, other studies suggest that donors experience less depression or a nonsignificant increase in depression symptoms (7,29,30), better social function, less bodily pain and more vitality than controls or patients undergoing nephrectomy for medical reasons (31). Stable psychiatric conditions were not associated with significant worsening of symptoms at the time of donor surgery (32).…”

Section: Discussionsupporting

confidence: 93%

Emotional Well-Being of Living Kidney Donors: Findings From the RELIVE Study

Jowsey

Jacobs

Gross

et al. 2014

American Journal of Transplantation

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Following kidney donation, short-term quality of life outcomes compare favorably to US normative data but long-term effects on mood are not known. In the Renal and Lung Living Donors Evaluation Study (RELIVE), records from donations performed 1963–2005 were reviewed for depression and antidepressant use pre-donation. Post-donation, in a cross-sectional cohort design 2010–2012, donors completed the Patient Health Questionnaire (PHQ-9) depression screening instrument, the Life Orientation Test-Revised, 36-Item Short Form Health Survey, and donation experience questions. Of 6,909 eligible donors, 3,470 were contacted and 2,455 participated (71%). The percent with depressive symptoms (8%; PHQ-9>10) was similar to National Health and Nutrition Examination Survey participants (7%, p=0.30). Pre-donation psychiatric disorders were more common in unrelated than related donors (p=0.05). Post-donation predictors of depressive symptoms included non-white race OR=2.00, p=0.020), younger age at donation (OR=1.33 per 10 years, p-0.002), longer recovery time from donation (OR=1.74, p=0.0009), greater financial burden (OR=1.32, p=0.013), and feeling morally obligated to donate (OR=1.23, p=0.003). While cross-sectional prevalence of depression is comparable to population normative data, some factors identifiable around time of donation, including longer recovery, financial stressors, younger age, and moral obligation to donate may identify donors more likely to develop future depression, providing an opportunity for intervention.

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Section: Discussionsupporting

confidence: 93%

Emotional Well-Being of Living Kidney Donors: Findings From the RELIVE Study

Jowsey

Jacobs

Gross

et al. 2014

American Journal of Transplantation

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“…In 2011, Maglakelidze et al 5 presented a prospective study of 57 donors with a surgical control group of 52 patients undergoing nephrectomy or partial nephrectomy for renal tumors. Results of MCH or PCH were not reported, but some individual domains of the SF-36 survey were better for the donor group at a mean follow-up of 32 months.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life Following Laparoscopic Living-Donor Nephrectomy

Bahler

Sundaram

2013

JSLS

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“…Maglakelidze et al . () found that in SF, BP and VT domains, donors have scored significantly better than healthy controls or patients undergoing nephrectomy for renal tumours. Results from the study of Reimer et al .…”

Section: Discussionmentioning

confidence: 96%