Assessment of Health-Related Quality of Life in Renal Transplant Recipients and Dialysis Patients

Maglakelidze, N.; Pantsulaia, T.; Tchokhonelidze, Irma; Managadze, L.; Chkhotua, Archil

doi:10.1016/j.transproceed.2010.12.015

Cited by 96 publications

(66 citation statements)

References 13 publications

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“…6,7 Thus, the transplant recipients scored better quality of life in comparison with hemodialysis (HD) and peritoneal dialysis patients. 8,9 Hemodialysis patients have lower score in most of the scale than peritoneal dialysis patients, especially for mental functions. 6,7,10,11 There are a limited number of studies, which evaluate the impact of various HD treatments themselves on HRQOL.…”

Section: Introductionmentioning

confidence: 99%

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Knežević¹,

Djordjević²,

Radovanovic-Velickovic³

et al. 2012

Renal Failure

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Background: The quality of life in patients undergoing hemodialysis is significantly disturbed. There are data that hemodiafiltration (HDF) may be more effective than conventional hemodialysis in the removal of uremic toxins and may reduce frequency and severity of intradialytic and postdialysis adverse symptoms in patients. Also, some researchers suggest advantages of using high-flux membranes compared with low-flux. Objective: The aim of this study was to examine whether hemodialysis modality and membrane flux, independent of membrane biocompatibility, make differences in quality of life in patients. Methods: In our cross-sectional study, we evaluated 124 patients who were divided, based on therapy, into three groups: online HDF, high-flux hemodialysis, and low-flux hemodialysis. Data were collected using the Short Form-36 questionnaire combined with special questionnaire, which included demographic and clinically related questions. Results: Health-related quality of life was better in patients on HDF compared with patients on hemodialysis, especially compared with low-flux hemodialysis patients in most of the scales and in both dimensions: physical component scale and mental component scale. There were no statistically significant differences in Short Form-36 domains between high-flux hemodialysis and low-flux hemodialysis. Conclusion: Our data suggest the potential advantages of HDF with regard to influence on quality of life, which is sufficient to justify further research in prospective and longitudinal study design.

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Section: Introductionmentioning

confidence: 99%

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Knežević¹,

Djordjević²,

Radovanovic-Velickovic³

et al. 2012

Renal Failure

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“…Kidney transplantation (KTx) has been demonstrated to be the most effective renal replacement therapy (RRT) for patients with an end-stage renal disease (ESRD) in terms of life expectancy (1-3), quality of life (4)(5)(6)(7)(8), and cost (9)(10)(11). Despite sustained efforts to improve organ donation and retrieval, supply still fails to cover ever-increasing needs for organs for transplantation in many countries (12,13).…”

Section: Introductionmentioning

confidence: 99%

Individual and Regional Factors of Access to the Renal Transplant Waiting List in France in a Cohort of Dialyzed Patients

Bayat

Macher

Couchoud

et al. 2015

American Journal of Transplantation

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Several studies have investigated geographical variations in access to renal transplant waiting lists, but none has assessed the impact on these variations of factors at both the patient and geographic levels. The objective of our study was to identify medical and nonmedical factors at both these levels associated with these geographical variations in waiting-list placement in France. We included all incident patients aged 18-80 years in 11 French regions who started dialysis between January 1, 2006, and December 31, 2008. Both a multilevel Cox model with shared frailty and a competing risks model were used for the analyses. At the patient level, old age, comorbidities, diabetic nephropathy, non-autonomous first dialysis, and female gender were the major determinants of a lower probability of being waitlisted. At the regional level, the only factor associated with this probability was an increase in the number of patients on the waiting list from 2005 to 2009. This finding supports a slight but significant impact of a regional organ shortage on waitlisting practices. Our findings demonstrate that patients' age has a major impact on waitlisting practices, even for patients with no comorbidity or disability, whose survival would likely be improved by transplantation compared with dialysis.

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“…[4][5][6][7][8][9] A number of studies have indicated that the QOL of dialysis patients is greatly impaired compared to general population. 10,11 However, differences in QOL between PD and HD patients have not been clearly identified. Few studies have examined the factors contributing to QOL of dialysis patients in the Chinese population.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life in Peritoneal and Hemodialysis Patients in China

Cui

Gao

et al. 2013

Renal Failure

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Background: Much attention has been paid to the quality of life (QOL) in dialysis patients worldwide. However, differences in QOL between peritoneal dialysis (PD) and hemodialysis (HD) patients have not been clearly identified. The objectives of this study were to compare the differences of QOL between PD and HD patients, and to investigate factors contributing to QOL in the Chinese population. Methods: All patients who received PD or HD more than 3 months were enrolled in the study. The demographic and clinical data were also obtained. SF-36 was used to assess QOL. Results: A total of 190 (91.8%) of 207 dialysis patients were enrolled in the study. PD patients had markedly lower scores on role-physical (RP) and bodily pain (BP) domains than HD patients, but had remarkably higher scores on role-emotional (RE) domain (p < 0.05). While the scores of physical component summary (PCS) and mental component summary (MCS) showed no differences between the two groups (p > 0.05). The results of the multiple linear regression analysis indicated that age and cerebrovascular disease had negative correlations with PCS (p < 0.01), whereas the serum prealbumin level had positive correlation with PCS (p < 0.05). The married status was negatively associated with MCS (p < 0.01). But the higher education level was positively associated with MCS (p < 0.01). Conclusions: There were no significant differences on QOL between the two dialysis modalities. The possible factors related to QOL were age, cerebrovascular disease, marital status, education, and serum prealbumin levels.

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Assessment of Health-Related Quality of Life in Renal Transplant Recipients and Dialysis Patients

Cited by 96 publications

References 13 publications

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Influence of Dialysis Modality and Membrane Flux on Quality of Life in Hemodialysis Patients

Individual and Regional Factors of Access to the Renal Transplant Waiting List in France in a Cohort of Dialyzed Patients

Quality of Life in Peritoneal and Hemodialysis Patients in China

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