Assessment of health‐related quality of life in Egyptian HCV‐infected recipients after living donor liver transplantation

El-Meteini, Mahmoud; Montasser, Iman Fawzy; Gendy, Eman El; Dabbous, Hany; Hashem, Rania; William, Peter; Bahaa, Mohamed; Sakr, M. S.

doi:10.1111/1751-2980.12293

Cited by 3 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to our findings, some other studies have documented a significant QOL improvement of recipients of LDLT. El-Meteini et al have shown improvement in all eight domains evaluated six months after LT by the Short-Form 36 of all 35 patients subjected to LDLT in Egypt (5) . Kawagishi et al have demonstrated that most children who underwent LDLT had normal school achievements and physical development more than 10 years after LT.…”

Section: Discussionmentioning

confidence: 99%

“…The goal of LT is not only to obtain long survival rate, but also to achieve an excellent QOL in all aspects, including physical, psychological, and social domains. With the significant improvement in survival of patients undergoing LT in the last decades, several transplantation centers and government and insurance health organizations have begun to focus attention on QOL after LT (5,24,25) . The evaluation and applications of QOL after LT have expanded dramatically in the last years (11,12) .…”

Section: Discussionmentioning

confidence: 99%

“…The few publications on QOL after LDLT are limited either to one or few QOL domains assessed or to patients with follow-up less than 5 years after LT (5,24,25) . Our study assessed all eight QOL domains of LDLT recipients with more than 10 years of successful transplantation.…”

Section: Discussionmentioning

confidence: 99%

“…The aim of this questionnaire is to assess differences of various domains of QOL (physical, functional, emotional and social aspects) between the general population and patients affected by a specific condition. This health survey is the most frequently employed QOL method to evaluate liver transplant recipients (5,6) . SF-36 is a generic, self-rated health survey designed to compare health status across diverse populations.…”

Section: Questionnairementioning

confidence: 99%

See 3 more Smart Citations

Good Quality of Life After More Than a Decade of Living Donor Liver Transplantation

Nogueira

Coelho

Domingos

et al. 2021

Arq. Gastroenterol.

View full text Add to dashboard Cite

BACKGROUND: Receptors of living donor liver transplantation (LDLT) have higher rate of postoperative biliary and vascular complications that may reduce posttransplant quality of life (QOL) due to the need of invasive and repetitive treatments. OBJECTIVE: The purpose of our study is to assess the various aspects of QOL of receptors undergoing LDLT after 10 years of transplantation and to identify potential factors that might be associated with impaired QOL. METHODS: Data of all patients with more than 10 years of LDLT were retrospectively evaluated. Patients were interviewed through a quality of life questionnaire (SF-36). RESULTS: From a total of 440 LT performed in 17 years (from September 1991 through December 2008), 78 patients underwent LDLT, of which 27 were alive and 25 answered completely the questionnaire. There were 17 (68%) men and 8 (32%) women, with a mean age of 38.6±18.5 years at the time of transplantation and mean follow up time of 15.1±1.9 years. The average MELD was 16.4±4.9 and the main indication for LT was hepatic cirrhosis caused by hepatitis B virus (32%). When compared to the general population, LDLT patients had lower mental health score (66.4 vs 74.5, P=0.0093) and higher vitality score (87.8 vs 71.9, P<0.001), functional aspects (94.6 vs 75.5, P=0.002), social aspects (93 vs 83.9, P=0.005), physical aspects (92 vs 77.5, P=0.006), and emotional aspects (97.33 vs 81.7, P<0.001). General health status (73.28 vs 70.2, P=0.074) and pain (78.72 vs 76.7, P=0.672) scores were similar in both groups. CONCLUSION: It is concluded that the various aspects LDLT recipients’ QOF are similar to those of the general population more than a decade after the transplant, except for the mental health domain which is lower.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Questionnairementioning

confidence: 99%

See 2 more Smart Citations

Good Quality of Life After More Than a Decade of Living Donor Liver Transplantation

Nogueira

Coelho

Domingos

et al. 2021

Arq. Gastroenterol.

View full text Add to dashboard Cite

show abstract

Effect of Ramadan fasting on Muslim recipients after living donor liver transplantation: A single center study

Montasser

Dabbous

Sakr

et al. 2020

Arab Journal of Gastroenterology

View full text Add to dashboard Cite

The Psychosocial Burden of HCV Infection and the Impact of Antiviral Therapy on the Quality of Life in Liver and Kidney Transplant Recipients: A Pilot Study

Santonicola

Bilancio

Zingone

et al. 2020

Gastroenterology Research and Practice

View full text Add to dashboard Cite

Background. Therapy with direct-acting antivirals (DAA) for HCV is safe and effective in the liver (LT) and kidney transplant (KT) recipients; however, data on the quality of life (QoL) of patients are scanty. This pilot study is aimed at prospectively evaluating the QoL in LT and KT recipients before and after DAA treatment. Methods. We prospectively enrolled 17 LT and 11 KT recipients with HCV infection starting a sofosbuvir-based antiviral therapy for 12 weeks. All participants before (T0), 12 (T12), and 24 (T24) weeks after the end of the therapy completed the Short Form Health Survey (SF-36) questionnaire, the Zung Self-rating Depression Scale, and State-Trait Anxiety Inventory (STAI—Y1–Y2). Results. At T0, LT and KT patients were similar for gender, age, BMI, smoking habits, marital status, mean liver stiffness values at Fibroscan, and HCV genotype distribution ( p > 0.05 ). There were no significant differences between the 2 groups in STAI-Y1, STAI-Y2, Zung, and SF-36 scores ( p > 0.05 ). At T12, all the participants showed a sustained virological response (SVR). All items of the SF-36 questionnaire improved from the pretreatment to posttreatment period within the LT group, and the 4 domains role-physical, bodily pain, social function, role-emotional, and mental health reached statistical significance ( p < 0.05 in all cases). On the contrary, in KT patients, there was no significant improvement in SF-36 mean scores compared to at baseline at T12 and T24. Conclusions. This pilot study suggested that DAA therapy is associated with a significant improvement of the QoL only in LT recipients. Probably, KT recipients did not consider HCV a “central player” in the course of their disease, and HCV eradication did not significantly impact on their QoL.

show abstract

Assessment of health‐related quality of life in Egyptian HCV‐infected recipients after living donor liver transplantation

Abstract: HRQOL is an important aspect of liver transplantation that should not be neglected.

Cited by 3 publications

References 24 publications

Good Quality of Life After More Than a Decade of Living Donor Liver Transplantation

Good Quality of Life After More Than a Decade of Living Donor Liver Transplantation

Effect of Ramadan fasting on Muslim recipients after living donor liver transplantation: A single center study

The Psychosocial Burden of HCV Infection and the Impact of Antiviral Therapy on the Quality of Life in Liver and Kidney Transplant Recipients: A Pilot Study

Contact Info

Product

Resources

About