Assessment of drug related problems among type 2 diabetes mellitus patients with hypertension in Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia

Abstract

ObjectiveThis study was conducted to assess magnitude and pattern of drug related problems among patients with type 2 diabetes mellitus (T2DM) and hypertension.ResultsThis study identified 364 drug related problems (DRPs) across the three categories of drug related problems, giving an average of 1.8 DRPs per patient. The effect of drug treatment being not optimal 179 (49.2%), untreated indication and symptoms 77 (21.1%), unnecessary drug-treatment 39 (10.7%) and adverse drug reactions 69 (19%) were the most frequent categories of DRPs identified. In general, high prevalence of drug-related problems was identified among patients with T2DM hypertension. The effect of drug treatment being not optimal, untreated indication and symptoms, unnecessary drug-treatment and adverse drug reactions were the most frequent categories of drug related problems identified. Therefore, the clinicians should work to improve patient care through prevention and resolving drug related problems since it can affect the quality of the care significantly.

<p>Drug-Related Problems and Their Predictors Among Patients with Diabetes Attending the Ambulatory Clinic of Gebre Tsadik Shawo General Hospital, Southwest Ethiopia</p>

“…This finding is in contrast to a study done in Jordan (81%) and Southeast Ethiopia (88%). 8,15 The difference might be due to the previous studies use of different DRPs identification and classification methods. Previous studies used the Cipolle and Strand classification method of DRPs, whereas the current study used the PCNE classification method.…”

“…The data collection tool was developed by reviewing different reports for important variables that have been used to assess drug-related problems and its predictors. 10,15,17 Patients were interviewed face-to face to fill out their socio-demographic and drug use-elated information. The main content of the tool included sociodemographic characteristics (age, sex, marital status, occupational status, educational status, smoking status, alcohol status, khat chewing) and clinical and drugrelated characteristics (family history, comorbidities, duration of diabetes, type of diabetes, status of glycemic control, complications, number of drugs prescribed, and type of drugs).…”

“…11,12 In Ethiopia, the majority of studies related to DRPs in diabetic patients were conducted among patients with type 2 diabetes. [13][14][15] However, understanding the magnitude of the DRPs and their predictors among patients with type 1 and type 2 diabetes would be important in achieving the desired therapeutic outcome. 16 In addition, it may be helpful to reveal the gap in pharmaceutical care service so as to empower the focus of healthcare providers and policy makers in designing strategies to prevent the occurrence of DRP.…”

The problem of polypragmasia in the group of elderly people. The case of a 62‑year‑old woman

“…Przeprowadzenie przeglądu lekowego u 62let niej pacjentki pozwoliło na wykrycie pięciu pro blemów lekowych. Podobnie jak w przypadku badania przeprowadzonego u pacjentów cho rych na cukrzycę typu 2. i nadciśnienie tętnicze, problemami, które zidentyfikowano były: nie skuteczna farmakoterapia, nieleczone wskazania i objawy, zbędne przyjmowanie leków oraz dzia łania niepożądane leków [5].…”

A cross-sectional study to assess the magnitude of Hypertension and Type 2 Diabetes Mellitus in Hatcliffe, Harare

“…The prevalence of the 'toxic combination' of HTN and T2DM was reported to be equal to T2DM alone in Cameroon (9).HTN and T2DM are important risk factors for cardiovascular diseases which overlap and have a common pathophysiology (9)(10)(11) . Hypertension is common in individuals that have already developed T2DM (12).Projections indicate that by 2035, SSA will have 41 million people with T2DM (13). Other projections indicate that by 2025 ,125million people in SSA will have HTN (14).…”