Assessment of cypermethrin induced hepatic toxicity in Catla catla: A multiple biomarker approach

Sharma, Ritu; Jindal, Ravul

doi:10.1016/j.envres.2020.109359

Cited by 38 publications

(12 citation statements)

References 44 publications

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“…This indicated that GST was induced either by GSH conjugation or by the detoxification of hydroperoxides [ 54 ]. Our result was in parallel with the finding of Nataraj et al [ 54 ], in the liver of L. rohita exposed to profenofos; in the liver of Catla catla exposed to cypermethrin [ 58 ], in the hepatopancreas of Astacuslepto dactylus exposed to azoxystrobin [ 59 ] and in the gill, liver, kidney, brain, heart, and muscle tissue of L. rohita exposed to endosulfan and chlorpyrifos [ 60 ].…”

Section: Discussionsupporting

confidence: 90%

Assessment of the effect of sub-lethal acute toxicity of Emamectin benzoate in Labeo rohita using multiple biomarker approach

et al. 2022

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Section: Discussionsupporting

confidence: 90%

Assessment of the effect of sub-lethal acute toxicity of Emamectin benzoate in Labeo rohita using multiple biomarker approach

et al. 2022

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“…Moreover, CYP induced behavioral changes in Nile tilapia [128], developmental toxicity of zebrafish [129], immunotoxicity of common carp [32], neurotoxicity of Catla [35], genotoxicity [29,30,33,130], and oxidative stress damage [131,132]. Furthermore, CYP induced serious histopathological alterations of African catfish [133], Nile tilapia [134], common carp [33], and Catla [34].…”

Section: Cypermethrin (Cyp) [(Rs)-cyano-(3-phenoxyphenyl) Methyl-(irs)-cis -Transmentioning

confidence: 99%

“…Studies showed that CYP induced genotoxicity and oxidative stress in the exposed zebrafish (Danio rerio) [29,30], malformations in rohu (Labeo rohita) during the early developmental stages [31], immunotoxic effects in common carp (Cyprinus carpio) [32], DNA damage, apoptosis, and histopathological alterations in C. carpio [33], hepatotoxicity in the Catla (Catla catla) [34], and neurotoxicity and apoptotic changes in the brain of C. catla [35].…”

Section: Introductionmentioning

confidence: 99%

An Overview on the Potential Hazards of Pyrethroid Insecticides in Fish, with Special Emphasis on Cypermethrin Toxicity

Farag

Alagawany

Bilal

et al. 2021

Animals

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Pesticides are chemicals used to control pests, such as aquatic weeds, insects, aquatic snails, and plant diseases. They are extensively used in forestry, agriculture, veterinary practices, and of great public health importance. Pesticides can be categorized according to their use into three major types (namely insecticides, herbicides, and fungicides). Water contamination by pesticides is known to induce harmful impacts on the production, reproduction, and survivability of living aquatic organisms, such as algae, aquatic plants, and fish (shellfish and finfish species). The literature and information present in this review article facilitate evaluating the toxic effects from exposure to various fish species to different concentrations of pesticides. Moreover, a brief overview of sources, classification, mechanisms of action, and toxicity signs of pyrethroid insecticides in several fish species will be illustrated with special emphasis on Cypermethrin toxicity.

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Section: вступunclassified

“…Найбільш вивченою реакцією на присутність пестицидів у клітинах є підвищення вмісту реактивних сполук кисню (РСК) і, як наслідок, розвиток окиснювального стресу (Sharma & Jindal, 2020;Yang et al, 2020). Реакцію антиоксидантних систем на вплив пестицидів запропоновано використовувати як біомаркери токсичного впливу (Sharma & Jindal, 2020). Однак модуляція активності антиоксидантних ферментів ушкоджуючими факторами має спільні риси, що не залежить від природи токсичної речовини (Pillet et al, 2019;Valavanidis, 2006).…”

Section: вступunclassified

Influence of the Insecticide ?-cyhalothrin on Oxidative Stress and Expression of Replicative Protein A in the Brain of Fish

Nedzvetsky¹,

Gasso²,

Novitskyi³

et al. 2020

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Anthropogenic pollution of natural waters by pesticides became a global problem with the beginning of their widespread use in the 1960s of the twentieth century. The most studied cells’ response to the pesticides is an increase in the content of reactive oxygen species (ROS) and, as a consequence, the development of oxidative stress. The proliferative activity of cells is regulated by various factors and largely depends on the expression of proteins involved in the DNA replication. Among such proteins are replicative proteins A (RPA), which binds single-stranded DNA (ssDNA) of eukaryotes. Disruption of RPA-associated cellular activity initiates genomic imbalance, so the expression and content of RPA1 serves as a marker not only of the cell cycle stability, but also the relevant response to DNA damage caused by ecotoxicants.The aim of our study is to determine the oxidative stress development and the RPA1 protein state as a response of rainbow trout’s brain cells to the influence of sublethal concentrations of the lambda-cyhalothrin. A model experiment on the neurotoxicity of lambda-cyhalothrin was performed on the rainbow trout (Oncorhynchus mykiss) under experimental conditions in a la-boratory. The obtained results indicate that sublethal concentrations of lambda-cyhalothrin in the water induce a significant increase in ROS generation in the rainbow trout’s brain. It was found that the content of ROS in the fish brain in all experimental groups depends on both the lambda-cyhalothrin concentration and the duration of exposure to the pesticide. Oxidative stress under the influence of lambda-cyhalothrin increases the content of stress-regulating protein RPA1 in the fish brain, inhibits transcriptional activity and limits the DNA breaks repair, which, in turn, can lead to genomic instability and activation of apoptosis. This indicates a high sensitivity of the mechanism of DNA replication to the neurotoxic effect of synthetic pyrethroids. Thus, the detected increased expression of RPA1 protein may be an adequate biomarker of cellular response to the toxic effects of synthetic pyrethroids in the brain of fish. Further studies of the effect of pyrethroids on key proteins of the aquatic organisms’ reaction to intoxication are of great importance for the determination of indicative biomarkers of pesticide pollution and its potential risk

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Assessment of cypermethrin induced hepatic toxicity in Catla catla: A multiple biomarker approach

Cited by 38 publications

References 44 publications

Assessment of the effect of sub-lethal acute toxicity of Emamectin benzoate in Labeo rohita using multiple biomarker approach

Assessment of the effect of sub-lethal acute toxicity of Emamectin benzoate in Labeo rohita using multiple biomarker approach

An Overview on the Potential Hazards of Pyrethroid Insecticides in Fish, with Special Emphasis on Cypermethrin Toxicity

Influence of the Insecticide ?-cyhalothrin on Oxidative Stress and Expression of Replicative Protein A in the Brain of Fish

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