Assessment of Corneal Densitometry in Rheumatoid Arthritis Patients

Anayol, Mustafa Alpaslan; Bostanci, Başak; Şekeroğlu, Mehmet Ali; Şimşek, Mert; Günaydın, Süleyman; Yılmazbaş, Pelin

doi:10.4274/tjo.89577

Cited by 24 publications

(20 citation statements)

References 20 publications

(20 reference statements)

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“…In previous studies, HM eyes were reported to have different cornea-related parameters, such as corneal curvature, corneal thickness, corneal endothelial density, corneal hysteresis, and corneal resistance factor, compared with normal eyes [ 4 , 5 , 8 , 16 – 19 ]. Clinical analysis of corneal light backscatter played an important role in the evaluation of the corneal status and in monitoring the progression of some corneal diseases [ 11 – 15 ]. In our study, we found a decrease in light backscatter in the central cornea (10 mm in diameter) and total diameter in the HM group.…”

Section: Discussionmentioning

confidence: 99%

“…Corneal densitometry, as an indicator for corneal health, has many applications in corneal diagnosis, such as the diagnosis of bacterial keratitis, keratoconus, pseudoexfoliation syndrome, Fuchs endothelial dystrophy, and rheumatoid arthritis, etc. [ 11 – 15 ] The use of this technique to assess corneal transparency in HM patients has not been reported before, and this technique may provide some useful information when assessing the corneal clarity of HM eyes. The aim of this study was to perform corneal densitometry of normal and HM corneas, to investigate the imaging capabilities of Pentacam in patients with HM and the potential differences in corneal densitometry values between normal and HM eyes.…”

Section: Introductionmentioning

confidence: 99%

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Corneal densitometry in high myopia

Dong

Zhang

et al. 2018

BMC Ophthalmol

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BackgroundTo investigate corneal densitometry values obtained using Scheimpflug tomography in normal and highly myopic (HM) eyes and to assess the differences in densitometry values between them.MethodsHighly myopic and normal corneas were examined using the Pentacam Scheimpflug imaging system. Corneal densitometry was automatically performed over a 12-mm diameter area, which was divided on the basis of annular concentric zones (0–2 mm, 2–6 mm, 6–10 mm, 10–12 mm, total diameter) and depth (anterior layer: inner 120 μm; center layer: from 120 μm to the last 60 μm; posterior layer: last 60 μm; total corneal thickness).ResultsA total of 100 normal and 100 HM eyes were enrolled in this study. Upon total corneal thickness densitometry, the HM group was found to have significantly lower values compared with the normal group in 4 annuli, including the 2 mm central zone, 2-6 mm zone, 6–10 mm zone, and 0–12 mm total diameter. Upon anterior layer densitometry, the HM group demonstrated statistically lower values in the 2-6 mm and 6–10 mm zones. Upon densitometry of the central and posterior layers, the HM group was found to have lower values in all annuli.ConclusionsThe densitometry map reveals that light backscatter was lower in most portions of the HM cornea than in the normal cornea.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Corneal densitometry in high myopia

Dong

Zhang

et al. 2018

BMC Ophthalmol

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“…Significant CD changes were seen 1 month onwards after PCRIs compared to 3 month onwards in tIOL group. CD has been studied on patients with general systemic diseases such as type 1 diabetes mellitus [13] and rheumatoid arthritis [14] as well as in some ocular conditions like bacterial keratitis [4], Fuchs' endothelial dystrophy [15] and keratoconus [16]. The changes in CD can occur due to various corneal refractive surgeries.…”

Section: Discussionmentioning

confidence: 99%

Influence of peripheral corneal relaxing incisions during cataract surgery for corneal astigmatism up to 2.5 dioptres on corneal densitometry

Zukaite

Bedi

Ali

et al. 2019

Eye

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To assess the effect of peripheral corneal relaxing incisions (PCRI) for astigmatism between 0.75 and 2.5 dioptres during cataract surgery on corneal densitometry (CD). Methods: In this prospective, randomised study, 80 eyes (80 patients), received either tIOL or PCRI. Assessment at preoperative and 1, 3, 6, 12 months post-operative visit included uncorrected (UCDVA) and best-corrected distance visual acuity (BCDVA), spherical equivalent (SEQ) (only post-operatively), mean anterior and posterior keratometric astigmatism (K A) and CD with Schiempflug system. CD was analysed in four concentric radial zones from centre to periphery (Zone 1 to 4) and in 3 layers (anterior, mid-stromal and posterior). Results: Comparing tIOLs vs. PCRIs, there was no significant difference in the UCDVA, BCDVA and SEQ. In PCRI group, anterior K A decreased at 1 month and remained stable thereafter. For zones 1, 2 and 3, CD significantly reduced after 3 months with tIOLs whereas with PCRIs, it reduced 1 month onwards. For zone 4, CD reduced only at 12 months with tIOLs compared to 3 months onwards with PCRIs. In both groups CD was higher in the zone 4 and anterior layer. Significant reduction in CD was found in all three layers of cornea after 3 months in tIOL and after first month in PCRI groups, respectively. Conclusions: Cataract surgery alone reduces the CD. Reducing keratometric astigmatism with PCRIs shows significant differences in CD from early post-operative period for central and anterior corneal layer.

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“…Corneal and lens densitometry became popular in recent years to evaluate corneal health in various ocular and systemic disorders. Subclinical corneal and lens densitometry changes were detected in cases with type one-type two diabetes mellitus, rheumatoid arthritis, and Wilson disease [16][17][18][19]. A recently published report about corneal clarity changes in VKC patients showed increased corneal, and lens densitometry in VKC cases as the disease's clinical-grade severity worsens [20].…”

Section: Introductionmentioning

confidence: 99%

Corneal and lens densitometry in patients with vernal keratoconjunctivitis

Yılmaz¹,

İpek²,

Özer

2021

Int Ophthalmol

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Aim To evaluate corneal and crystalline lens densitometry in patients with vernal keratoconjunctivitis (VKC). Methods This is a case-control study. Patients with VKC and age-gender-matched healthy controls underwent a complete ophthalmologic examination with corneal and crystalline lens densitometry measurements. Additionally, the anterior chamber parameters comprise anterior and posterior K mean and astigmatism, anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pachymeter, and corneal volume (CV). Patients who had clinically grade 0 or grade 1 VKC and with only tarsal conjunctiva involvement during the conductance of the study were included. The variables were compared statistically. Results One hundred and nine eyes were included in the study, in which fifty-one were in the VKC group. There were 25 males in the VKC group (26 female) and 22 males in the control group (36 female). A statistically significant difference was found between the groups in terms of posterior corneal astigmatism (p = 0.02). The mean corneal pachymeter, CV, ACD, ACA, and ACV were similar in both groups (p = 0.63, p = 0.26, p = 0.60, p = 0.41, and p = 0.32, respectively). The total mean corneal densitometry in the zones extending from 6 to 10 mm and 10 to 12 mm was increased in the VKC group compared to the control group (p = 0.04 and p = 0.012, respectively). The mean crystalline lens was found to be denser in the VKC group compared to the control group (8.96 ± 1.6 vs. 8.5 ± 0.57, respectively, p = 0.04). Conclusion Posterior corneal astigmatism is increased in VKC cases in comparison with age-and gender-matched controls. The peripheral anterior 6-12 mm annular corneal zone showed increased corneal densitometry in VKC cases compared to the healthy subjects. Additionally, the lens clarity is found to be decreased subclinically in VKC cases compared to control cases. Keywords Vernal keratoconjunctivitis Á Corneal densitometry Á Crystalline lens densitometry Á Anterior chamber depth Á Anterior chamber volume Á Anterior chamber angle Á Pachymeter Á Corneal volume

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Assessment of Corneal Densitometry in Rheumatoid Arthritis Patients

Cited by 24 publications

References 20 publications

Corneal densitometry in high myopia

Corneal densitometry in high myopia

Influence of peripheral corneal relaxing incisions during cataract surgery for corneal astigmatism up to 2.5 dioptres on corneal densitometry

Corneal and lens densitometry in patients with vernal keratoconjunctivitis

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