Assessment of cognitive function in patients with alcohol dependence: A cross-sectional study

Sharma, Dalip; Padam, Anita; Gharu, Yuvraj; Sharma, Dinesh Dutt; Sharma, Sudhir

doi:10.5455/njppp.2018.8.0935121092017

Cited by 3 publications

(3 citation statements)

References 4 publications

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“…Based on the results of this study, many the café visitors have poor cognitive function, similar finding as shown in other big city in Indonesia, Yogyakarta. 12 This study also shows a strong association (p=0.000) between alcohol addiction and cognitive function among café visitors in Jakarta, which is consistent with the research conducted by Sharma et al 13 in 2017 that shows individuals with alcohol addiction with mean MoCA score 21.50 ±3.33, indicating poor cognitive function (p=0.000). Individual who consume large amounts of alcohol (≥36 grams pure alcohol per day) will experience a decline in cognitive function faster in the next 10 years.…”

Section: Discussionsupporting

confidence: 89%

Alcohol Addiction and Cognitive Function among Café Visitors at South Jakarta

Suwadi

Agus

Lembar

2019

amj

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Background: Alcohol addiction has an acute and chronic impact, and may cause cognitive function impairment, in the form of interference in decision making and impulse control, as well as impaired motor function. Furthermore, research on alcohol addiction and cognitive function has not been widely studied in Indonesia. The purpose of this study was to explore the association between alcohol addiction and cognitive function among café visitors at South Jakarta. Methods: This was a cross sectional study, conducted among cafévisitors at South Jakarta in 2018. The respondents of this study were individuals who have consumed alcohol in the last 12 months and not consumed narcotics, psychotropic, and other addictive substances except nicotine and caffeine. Alcohol addiction among respondent was assessed by the CAGE questionnaire and cognitive function was assessed by the MoCA-Ina questionnaire. Statistical analysis was determined by Chi Square test. Results: In total, 80 respondents consisting of 57 men and 23 women met the study criteria, 67.5% of respondents have experienced alcohol addiction and 85.2% have experienced poor cognitive function. There was a strong association between alcohol addiction and cognitive function among café visitors (p=0.000; OR=44.083). Conclusions: Individual with alcohol addiction has a poor cognitive function compared with people without alcohol addiction. Therefore, awareness of the adverse effects of alcohol addiction on cognitive function among community is needed and thus, people are expected to distance from alcohol addiction.

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Section: Discussionsupporting

confidence: 89%

Alcohol Addiction and Cognitive Function among Café Visitors at South Jakarta

Suwadi

Agus

Lembar

2019

amj

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“…31 Few studies have assessed cognitive performance through the MMSE, but in all studies lower scores were reported in individuals with SUD -including alcohol, crack cocaine, opioids, and methamphetamine, compared to controls. [17][18][19] The comparison between substances of preference was also conducted, although a similar MMSE performance was previously observed. 19,32 It is important to emphasize that most previous studies had smaller samples than ours, which could explain the minor discrepancies between these specific findings.…”

Section: Discussionmentioning

confidence: 84%

“…Lower MMSE scores have been observed among alcohol, crack cocaine, opioid, and methamphetamine users when compared to controls. [17][18][19] A previous study also demonstrated that MMSE could be used as a cognitive screening and criterion to include individuals with SUD that present more adherence in clinical trials. 20 In this sense, cognitive deficits may have a negative impact on several clinical outcomes, including treatment retention and adherence in individuals with alcohol addiction 21 and cocaine and amphetamine dependence.…”

Section: Introductionmentioning

confidence: 99%

Assessment of cognitive functioning using the Mini Mental State Examination in men with alcohol and crack cocaine use disorder

Schuch¹,

Becker²,

Rabelo‐da‐Ponte³

et al. 2023

Trends Psychiatry Psychother

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Introduction:The consumption of substances has been associated with cognitive impairment. The Mini Mental State Examination (MMSE) is an easy-to-apply screening used to assess cognitive functions. Our aim was to evaluate the cognitive performance of individuals with alcohol and/or crack cocaine use disorder (AUD, CUD, and polysubstance use) using the MMSE, and to investigate the impact of substance use profile, and the moderation effect of educational level on MMSE performance.Method: Cross-sectional study with 508 inpatient men, diagnosed with substance use disorders (245 with AUD, 85 with CUD and 178 with polysubstance use). Cognitive performance was assessed using the MMSE scale (total and composite scores).Results: Individuals with AUD yielded worse MMSE total score and in the three MMSE components (p<0.001, oral/written language comprehension, p<0.001, attention/memory, and p=0.007, motor functions) when compared to individuals with polysubstance use. MMSE scores were positively correlated to education level (p<0.017), but not associated with age, recent and years of drug use. Education level moderated the impact of substance use on MMSE performance, especially in total score and language comprehension composite score. Individuals with lower education levels (≤ 8 years) had worse performance than those with higher education (≥ 9 years), mainly in individuals with AUD (p<0.001).Discussion: Individuals with lower education level and alcohol use are more prone to present cognitive impairment than crack cocaine users, especially involving language aspects. A better-preserved cognitive function could impact treatment adherence and might guide the decision of therapeutic strategies.

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Thermal Degradation of Complexes Derived from Cu (II) Groundnut (Arachis hypogaea) and Sesame (Sesamum indicum) Soaps

Joram¹,

Sharma²,

Sharma³

2018

Zeitschrift Für Physikalische Chemie

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The complexes have been synthesized from Cu (II) soaps of groundnut (Arachis hypogaea) and sesame (Sesamum indicum) oils, with ligand containing nitrogen and sulfur atoms like 2-amino-6-methyl benzothiazole. The complexes were greenish brown in color. In order to study TGA, first characterized them by elemental analysis, and spectroscopic technique such as IR, NMR and ESR. From the analytical data, the stoichiometry’s of the complexes have been observed to be 1:1 (metal:ligand). These complexes have been thermally analyzed using TGA techniques to determine their energy of activation. These complexes show three step thermal degradation corresponding to fatty acid components of the edible oils and each complex has three decomposition steps in the range of 439–738 K. Various equations like Coats–Redfern (CR), Horowitz–Metzger (HM) and Broido equations (BE) were applied to evaluate the energy of activation. The values of energy of activation are observed to be in the following order for both copper groundnut benzothiazole (CGB) and copper sesame benzothiazole (CSeB) complexes: CGB > CSeB. CGB is observed to be more stable than CSeB due to its higher activation energy. The above studies would provide significant information regarding the applications of synthesized agrochemicals and their safe removal through parameters obtained in degradation curves and its relation with energy.

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Assessment of cognitive function in patients with alcohol dependence: A cross-sectional study

Cited by 3 publications

References 4 publications

Alcohol Addiction and Cognitive Function among Café Visitors at South Jakarta

Alcohol Addiction and Cognitive Function among Café Visitors at South Jakarta

Assessment of cognitive functioning using the Mini Mental State Examination in men with alcohol and crack cocaine use disorder

Thermal Degradation of Complexes Derived from Cu (II) Groundnut (Arachis hypogaea) and Sesame (Sesamum indicum) Soaps

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