Assessment of central corneal thickness, intraocular pressure and retinal nerve fiber layer thickness at women with polycystic ovary syndrome

Abstract

Objective: To compare intraocular pressure, central cornea thickness, anterior chamber depth, axial length and thickness of retina nerve fiber layer between women with polycystic ovary syndrome and healthy at the same age segment. Methods: Between August 2015-January 2016, 46 women who have polycystic ovary syndrome and 53 healthy women have been included to the study. After a complete ophthalmologic examination, intraocular pressure, central cornea thickness, anterior chamber depth, axial length and retinal nerve fiber layer thickness were investigated. In the statistical analysis of the data, Independent Samples t test was utilized to compare the groups. Results: While mean age was 23.4 ± 4.5 (16-35) in the group with polycystic ovary syndrome, average age level was found as 24.0 ± 6.1 (18-54) among the controls (P=0.549). Intraocular pressure values were measured and determined as 17.7 ± 2.6 mmHg in the group with polycystic ovary syndrome, while the values were 15.2 ± 2.4 mmHg in the controls (P <0,001). Although it was 79.4 ±10.2 µm in the group with polycystic ovary syndrome, retinal nerve fiber layer thickness in the nasal quadrant was found to be 73.8 ± 10.9 µm among the controls (P <0.001). Conclusion: We found that the increased levels seen in intraocular pressure and retinal nerve fiber layer thickness in the nasal quadrants of the patients with polycystic ovary syndrome were statistically significance. Hence, we recommend that the patients with polycystic ovary syndrome should be specially analyzed as to eye assessment.

Pregnancy-induced changes in ocular biomechanics are maternal hormone- related in healthy Chinese pregnant women

“…Teberik, K et. al [22] reported that the average thickness of the RNLF in the different sectors was signi cantly higher in women with polycystic ovary syndrome than in healthy women. Therefore, the growth of the axial length in this study may result from the concomitant increase in RNFL.…”