Assessment of Bulbar Redness with a Newly Developed Keratograph

Wu, Siqi; Hong, Jiaxu; Tian, Lijia; Cui, Xinhan; Sun, Jianguo; Xu, Jianjiang

doi:10.1097/opx.0000000000000643

Cited by 68 publications

(53 citation statements)

References 16 publications

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“…Unlike the image-based scales, keratograph is the first commercially available device which can evaluate bulbar redness via analyzing the captured images automatically and objectively. Wu et al, reported that its reproducibility was much higher than other three image-based scales for evaluating bulbar redness [31]. In our study, the bulbar redness score increased significantly within the 4 weeks postoperatively, but it recovered to the preoperative level at 8 weeks postoperatively.…”

Section: Discussioncontrasting

confidence: 53%

Influence of Pars Plana Vitrectomy on Ocular Surface using Non-Invasive Keratograph 5M

Fan

Liu

Gao

et al. 2018

Preprint

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Background: The noninvasive Keratography has been used in evaluating surgery-induced ocular surface changes, while few were known about the influence of pars plana vitrectomy (PPV) on ocular surface. This study aimed to evaluate the influence of PPV on ocular surface using Keratograph 5M. Methods: 30 patients (30 eyes) undergoing primary PPV were recruited in the study. Ocular Surface Disease Index (OSDI) questionnaire was performed. Ocular surface parameters, including tear meniscus height (TMH), noninvasive tear break up time (NITBUT) and bulbar redness score were obtained preoperatively, at 1 week, 2 weeks, 4 weeks, 8 weeks and 12 weeks postoperatively by Keratograph 5M. Correlations between all the clinical parameters were analyzed further. Results: The percentages of both photophobia and gritty within 4 weeks after PPV were significantly higher than preoperation, while they decreased to the preoperative levels at both 8 weeks and 12 weeks postoperatively. The percentage of sore eyes within 2 weeks postoperatively was significantly higher than preoperation, but there were no significant differences between the percentages of preoperation and 4 weeks, 8 weeks and 12 weeks postoperatively. OSDI score increased significantly within 8 weeks postoperatively, but it returned to the preoperative level at 12 weeks. TMH was increased significantly at the first week after PPV, and recoverd to preoperative level at 2 weeks postoperatively. Both NITBUT-first and NITBUT-average shortened significantly within 8 weeks postoperatively, but they gradually improved to the preoperative levels at 12 weeks. Bulbar redness score was significantly higher than preoperative level within 4 weeks postoperatively, but it returned to the preoperative level at 8 weeks. NITBUT-first and NITBUT-average had a significant positive correlation at each visit. OSDI score had a significant positive correlation with bulbar redness, and TMH had a significant positive correlation with NITBUT-average at both 1 week and 2 weeks postoperatively. Conclusions: Keratograph 5M can provide a reliable noninvasive method to assess the influence of PPV on ocular surface. PPV may cause various changes in both symptoms and signs of ocular surface damages at an early stage, while all these changes will return to preoperative levels gradually at 12 weeks postoperatively.

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Section: Discussioncontrasting

confidence: 53%

Influence of Pars Plana Vitrectomy on Ocular Surface using Non-Invasive Keratograph 5M

Fan

Liu

Gao

et al. 2018

Preprint

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“…The results of tear film parameters were in accord with the subjective symptom melioration. The advanced placido topograph Keratograph 5 M, is a recommended device to measure NI-BUT and TMH [ 25 , 26 ], and it is also objective and reliable to score bulbar redness [ 27 ]. It has been a widely used tool to evaluate tear film and DE diagnosis in clinic [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Short-term effect of a developed warming moist chamber goggle for video display terminal-associated dry eye

et al. 2018

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BackgroundVideo display terminal (VDT)-associated dry eye (DE) patients are the rising group worldwide, and moisture goggles are the preferable treatment since they are capable of improving tear film stability and DE discomfort. The current study aims to evaluate the short-term efficacy and safety of the developed warming moist chamber goggles (WMCGs) for VDT-associated DE patients.MethodsIn this prospective self-control study, 22 DE patients (22 eyes) working with VDTs over 4 h daily were enrolled and instructed to wear WMCGs for 15 min. Sodium hyaluronate (SH, 0.1%) eyedrops were applied as a control on another day on these same patients, however 4 subjects denied the eyedrop application. The symptomatology visual analog scale (VAS) score, tear meniscus height (TMH), noninvasive tear film break-up time (NI-BUT), tear film lipid layer thickness (LLT), and bulbar conjunctival redness were assessed with Keratograph 5 M at baseline, 5, 30 and 60 min after treatment. The WMCGs wearing comfort was also evaluated.ResultsThe ocular discomfort evaluated by VAS decreased in the WMCGs group throughout 60 min (P<0.001), better than the control group levels (P ≤ 0.015). TMH, NI-BUT (including the first BUT and average BUT) increased than baseline level accross 60 min in the WMCG group (P ≤ 0.012), while those in the control group only showed temporary improvements in 5 min. LLT also increased obviously after WMCGs wear, while the change in the control group was nearly innoticeable. No adverse responses were detected.ConclusionsTemporary use of the WMCGs is able to relieve ocular discomfort, and improves tear film stability in DE patients for at least 1 h, making it a promising alternative to other treatments.

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“…A clinical evaluation was conducted one week and one month after wearing each contact lens type, bilaterally in randomised order, each for one month. Objective non-invasive break up time (NIKBUT), the average time of all break up incidents (NIKBUT average), and nasal and temporal bulbar and limbal redness (Jenvis grading scale) were evaluated in both eyes after at least one hour of lens settling and with the Keratograph 5M (OCULUS Optikgeraete GmbH, Wetzlar, Germany), previously shown to be repeatable (31). Three consecutive NIKBUT and NIKBUT average readings were taken separated by at least 60 seconds and the mean was recorded.…”

Section: Methodsmentioning

confidence: 99%

Effect of contact lens surface properties on comfort, tear stability and ocular physiology

Vidal-Rohr

Wolffsohn

Davies

et al. 2018

Contact Lens and Anterior Eye

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Assessment of Bulbar Redness with a Newly Developed Keratograph

Abstract: The OI is an objective and reliable method for scoring BR. Its reproducibility was the highest of all the four modalities. The keratograph is recommended, therefore, as a suitable alternative for BR assessment.

Cited by 68 publications

References 16 publications

Influence of Pars Plana Vitrectomy on Ocular Surface using Non-Invasive Keratograph 5M

Influence of Pars Plana Vitrectomy on Ocular Surface using Non-Invasive Keratograph 5M

Short-term effect of a developed warming moist chamber goggle for video display terminal-associated dry eye

Effect of contact lens surface properties on comfort, tear stability and ocular physiology

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