Assessment of breast cancer response to neoadjuvant chemotherapy: Is volumetric MRI a reliable tool?

18F-FDG PET/CT to Predict Response to Neoadjuvant Chemotherapy and Prognosis in Inflammatory Breast Cancer

“…In non-IBC, conventional imaging to assess response to NACT has shown discordant results (15), probably because of the inability to differentiate fibrosis and granulomatous tissue from viable tumor cells. Volumetric MR imaging appears to be a more reliable tool to monitor response to NACT (16), but no published data on IBC are available. In the present study, comparison of PET/CT to morphologic imaging results was not performed, because patients had either CT or MR imaging at the initial work-up.…”

Evaluation of CT as a predictor for kidney and renal artery mobility

“…The concordance correlation coefficient (CCC) and Pearson correlation coefficient (r) were used to assess intra-and inter-observer agreement in measuring the renal artery angle change and kidney mobility (34,35). The average value of each observer's two measurements was used for interobserver analysis.…”

Monitoring breast masses with ultrasound tomography in patients undergoing neoadjuvant chemotherapy

“…Accurate and frequent evaluation of a tumor's response to therapy is needed in order to minimize side effects, optimize treatment and plan for surgery. [12][13][14][15][16][17][18][19][20][21] Some patients exhibit complete pathological remission from receiving neoadjuvant chemotherapy (no cancer cells at time of surgery). Predicting such response early in the process may not only help reduce the duration of the chemotherapy and thereby obviate the morbidity associated with it in community breast cancer treatment, but also provide a reliable pharmacodynamic endpoint to assess or compare the clinical efficacy of a new therapeutic agent or regimen versus treatment approach under standard care.…”