Assessment of bacterial contamination of three multidose ophthalmic solutions

Abstract

We conclude that proparacaine, tropicamide, and eyewash solutions used in veterinary examination rooms are adequately preserved for use in ophthalmic examination. They have a low level of bacterial contamination 1 or 2 weeks after opening when used and stored according to the recommendations of the product manufacturers and previous studies.

Evaluation of microbial contamination of canine plasma eyedropper bottles following clinical use in canine patients

“…There are very few studies in the veterinary literature assessing microbial contamination of ophthalmic medications. One study by Betbeze et al in 2007 assessed bacterial contamination of three multidose ophthalmic solutions and found a very low level of contamination after 2 weeks of use . However, these solutions were pharmaceutical products that contained preservative and were used in the clinic by veterinary professionals.…”

“…One study by Betbeze et al in 2007 assessed bacterial contamination of three multidose ophthalmic solutions and found a very low level of contamination after 2 weeks of use. 13 However, these solutions were pharmaceutical products that contained preservative and were used in the clinic by veterinary professionals. Another study evaluated equine serum and concluded that it could be safely administered through a simulated subpalpebral lavage line without bacterial contamination.…”