Assessment of Autofluorescence to Detect the Remineralization Capabilities of Sodium Fluoride, Monofluorophosphate and Non-Fluoride Dentifrices

Feng, Yuanyuan; Yin, Wei; Hu, Deyu; Zhang, Y.P.; Ellwood, R.P.; Pretty, I A

doi:10.1159/000104793

Cited by 40 publications

(26 citation statements)

References 48 publications

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“…At a consensus meeting in 2002, The International Consensus Workshop on Caries Clinical Trials (ICW-CCT) [47], it was agreed that QLF may offer one solution in the effort to reduce both the number of subjects and the duration of caries clinical trials. The method seems to have been rapidly adopted as a standard reference measure in clinical tests of the efficacy of preventive measures [42, 48–50]. Application for quantification of dental fluorosis [51], erosive lesions [52, 53], and staining, and bleaching of teeth [54–56] has been investigated.…”

Section: Optical Caries Detection Methodsmentioning

confidence: 99%

Caries Detection Methods Based on Changes in Optical Properties between Healthy and Carious Tissue

Karlsson

2010

International Journal of Dentistry

117

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A conservative, noninvasive or minimally invasive approach to clinical management of dental caries requires diagnostic techniques capable of detecting and quantifying lesions at an early stage, when progression can be arrested or reversed. Objective evidence of initiation of the disease can be detected in the form of distinct changes in the optical properties of the affected tooth structure. Caries detection methods based on changes in a specific optical property are collectively referred to as optically based methods. This paper presents a simple overview of the feasibility of three such technologies for quantitative or semiquantitative assessment of caries lesions. Two of the techniques are well-established: quantitative light-induced fluorescence, which is used primarily in caries research, and laser-induced fluorescence, a commercially available method used in clinical dental practice. The third technique, based on near-infrared transillumination of dental enamel is in the developmental stages.

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Section: Optical Caries Detection Methodsmentioning

confidence: 99%

Caries Detection Methods Based on Changes in Optical Properties between Healthy and Carious Tissue

Karlsson

2010

International Journal of Dentistry

117

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“…50 QLF methodology could detect, within three-and six-month periods, a difference in remineralization between fluoride-containing and non-fluoride-containing dentifrices. 57 The demineralization and remineralization of intact root surface and cavitated caries lesions were determined using a QLF system, and the QLF system was able to detect early root surface caries lesions in vivo. 58 It was determined whether or not QLF parameters [area (A; mm 2 ), fluorescence loss (F; %), and Q (% × mm…”

Section: Fluorescence Of Dental Cariesmentioning

confidence: 99%

Fluorescence properties of human teeth and dental calculus for clinical applications

Lee¹

2015

J. Biomed. Opt

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Abstract. Fluorescent emission of human teeth and dental calculus is important for the esthetic rehabilitation of teeth, diagnosis of dental caries, and detection of dental calculus. The purposes of this review were to summarize the fluorescence and phosphorescence of human teeth by ambient ultraviolet (UV) light, to investigate the clinically relevant fluorescence measurement methods in dentistry, and to review the fluorescence of teeth and dental calculus by specific wavelength light. Dentine was three times more phosphorescent than enamel. When exposed to light sources containing UV components, the fluorescence of human teeth gives them the quality of vitality, and fluorescent emission with a peak of 440 nm is observed. Esthetic restorative materials should have fluorescence properties similar to those of natural teeth. Based on the fluorescence of teeth and restorative materials as determined with a spectrophotometer, a fluorescence parameter was defined. As to the fluorescence spectra by a specific wavelength, varied wavelengths were investigated for clinical applications, and several methods for the diagnosis of dental caries and the detection of dental calculus were developed. Since fluorescent properties of dental hard tissues have been used and would be expanded in diverse fields of clinical practice, these properties should be investigated further, embracing newly developed optical techniques.

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“…QLF has the advantage of being a nondestructive method that allows longitudinal analysis of tissues in vitro, in situ or in vivo [Higham et al, 2005]. QLF has also shown the ability to detect and quantify changes in mineral content and size of lesions by demonstrating a dose response between F and non-F dentifrices in short-term clinical trials [Tranaeus et al, 2001;Feng et al, 2007].…”

Section: Discussionmentioning

confidence: 99%

“…This method has been employed in pH-cycling experiments [Hafström-Björkman et al, 1992] and in monitoring in vivo remineralization of white spot lesions [AlKhateeb et al, 1998;Tranaeus et al, 2001;Feng et al, 2007;Karlsson, 2010]. The purpose of this study was to determine the ability of QLF to detect differences in remineralization of artificial caries lesions in a pH-cycling model using 3 types of silica-based NaF toothpastes (0 ppm, 550 ppm and 1,100 ppm) and compare changes to those measured using surface microhardness (SMH).…”

Section: Introductionmentioning

confidence: 99%

Quantitative Light-Induced Fluorescence to Measure Enamel Remineralization in vitro

et al. 2014

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The aim of this study was to compare the ability of quantitative light-induced fluorescence (QLF) and surface microhardness (SMH) to measure the remineralization of enamel subsurface lesions, using a pH-cycling model including treatment with 0-ppm, 550-ppm or 1,100-ppm sodium fluoride (NaF) dentifrices. Methods: Subsurface lesions were created in human enamel specimens (n = 36) and exposed to a remineralization pH-cycling model for 14 days. The pH-cycling model was performed in an automated system where specimens were subjected to a demineralizing solution for 20 min and treatment for 1 min and were then remineralized for 7 h 39 min, 3 times daily. The treatments consisted of 3 NaF, silica-containing dentifrices (0 ppm F; 550 ppm F; 1,100 ppm F). The outcome variables were: change from baseline in surface hardness and percentage change from baseline in fluorescence. An ANCOVA explored differences between different treatment groups (at the p < 0.05 level). Associations between QLF and SMH were evaluated using Spearman's correlation coefficient. Results: The percentage SMH changes were 14.9 ± 2.1%, 56.6 ± 9.6% and 103.9 ± 14.6% for the 0-, 550- and 1,100-ppm F dentifrices, respectively. The percentage fluorescence changes were 15.6 ± 7.1%, 59.8 ± 11.9% and 85 ± 13.2%, respectively. The differences between all pairwise comparisons were statistically significant for both methods (p = 0.001). QLF correlated with SMH (r = 0.67). Conclusions: Both the SMH and QLF methods demonstrated a significant F dose response for toothpaste in this in vitro remineralization model, and both methods were able to distinguish treatments with different F levels.

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Assessment of Autofluorescence to Detect the Remineralization Capabilities of Sodium Fluoride, Monofluorophosphate and Non-Fluoride Dentifrices

Cited by 40 publications

References 48 publications

Caries Detection Methods Based on Changes in Optical Properties between Healthy and Carious Tissue

Caries Detection Methods Based on Changes in Optical Properties between Healthy and Carious Tissue

Fluorescence properties of human teeth and dental calculus for clinical applications

Quantitative Light-Induced Fluorescence to Measure Enamel Remineralization in vitro

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