Assessing the risk of endogeneity bias in health and mortality inequalities research using composite measures of multiple deprivation which include health-related indicators: A case study using the Scottish Index of Multiple Deprivation and population health and mortality data

Bradford, Daniel R. R.; Allik, Mirjam; McMahon, Alex D.; Brown, Denise

doi:10.1016/j.healthplace.2023.102998

Cited by 4 publications

(1 citation statement)

References 39 publications

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“…While the SIMD contains a health domain and therefore the validity of using it to study associations of deprivation with health may be questioned, previous studies have indicated it to be highly correlated with the overall SIMD, and that its exclusion makes little difference to results. 17 , 44 Additionally, the SIMD's area-level nature also prevents distinguishing effects due to the patient's characteristics from area-level effects of their residential location. 38…”

Section: Discussionmentioning

confidence: 99%

Association of socioeconomic status with 30-day survival following out-of-hospital cardiac arrest in Scotland, 2011–2020

Bijman,

Chamberlain,

Clegg

et al. 2023

European Heart Journal - Quality of Care and Clinical Outcomes

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Background and aims The aim of this study was to investigate the crude and adjusted association of socioeconomic status with 30-day survival after out-of-hospital cardiac arrest (OHCA) in Scotland and to assess whether the effect of this association differs by sex or age. Methods This is a population-based, retrospective cohort study, including non-traumatic, non-Emergency Medical Services witnessed patients with OHCA where resuscitation was attempted by the Scottish Ambulance Service, between 1 April 2011 and 1 March 2020. Socioeconomic status was defined using the Scottish Index of Multiple Deprivation (SIMD). The primary outcome was 30-day survival after OHCA. Crude and adjusted associations of SIMD quintile with 30-day survival after OHCA were estimated using logistic regression. Effect modification by age and sex was assessed by stratification. Results Crude analysis showed lower odds of 30-day survival in the most deprived quintile relative to least deprived [odds ratio (OR) 0.74, 95% confidence interval (CI) 0.63–0.88]. Adjustment for age, sex, and urban/rural residency decreased the relative odds of survival further (OR 0.56, 95% CI 0.47–0.67). The strongest association was observed in males <45 years old. Across quintiles of increasing deprivation, evidence of decreasing trends in the proportion of those presenting with shockable initial cardiac rhythm, those receiving bystander cardiopulmonary resuscitation, and 30-day survival after OHCA were found. Conclusions Socioeconomic status is associated with 30-day survival after OHCA in Scotland, favouring people living in the least deprived areas. This was not explained by confounding due to age, sex, or urban/rural residency. The strongest association was observed in males <45 years old.

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Section: Discussionmentioning

confidence: 99%