Assessing the Metabolic Impact of Ground Chia Seed in Overweight and Obese Prepubescent Children: Results of a Double-Blind Randomized Clinical Trial

Abstract

Childhood obesity is a medical condition of major public health concern. Chia seeds are used to treat certain noncommunicable diseases, and they are rich in omega-3 fatty acids, which contribute to the absorption of vitamins. A randomized double-blind clinical trial of 30 obese children was performed. The sample was composed of prepubertal 5-to 10year-old children of both sexes with body mass indexes equal to or above the 95th percentile who were recruited through the Pediatric Department of the Faculdade de Medicina do ABC. Blood samples were drawn, the children were weighed and measured, and a 24-h dietary recall was obtained before and after the treatment. Not only were significant differences observed for fibrinogen (P = .011) but a correlation between the changes in markers and the presence of fibers was also observed for two inflammatory parameters: tumor necrosis factor-a (P = .027) and nuclear factor-jb (P = .059). These results indicate that chia seeds may have anti-inflammatory effects related to their fiber content in the context of childhood obesity.

Composición química, características nutricionales y beneficios asociados al consumo de chía (Salvia hispanica L.)

“…Por otro lado, en un ensayo clínico aleatorizado doble ciego realizado en 30 niños prepúberes con estado nutricional de sobrepeso y obesidad a los que se les sometió a un tratamiento diario con 25 g de semillas Datos expresados en gramos por cada 100 g de harina de chía. Fuente: Adaptación del trabajo de Da Silva et de chía molidas o placebo de almidón de maíz durante 75 días, no se encontraron diferencias significativas en el peso corporal ni en los parámetros bioquímicos, pero hubo una correlación estadísticamente significativa entre los biomarcadores inflamatorios, factor nuclear κB (de sus siglas en inglés, NF-κB) y factor de necrosis tumoral α (de sus siglas en inglés, TNF-α), y la presencia de fibra de las semillas de chía molida, indicando que pueden tener un efecto antiinflamatorio atribuible a la fibra en pacientes con exceso de peso 28 .…”

The protective effects of some herbs on mitigating HFD-induced obesity via enhancing biochemical indicators and fertility in female rats

“…Chia seeds were a notable dietary fibre source known for their ability to decrease appetite. Additionally, they contain omega-3 fatty acids, which play a vital role in emulsifying and absorbing liposoluble vitamins A, D, E, and K. Using chia seeds in meals can enhance their nutritional composition and mitigate the risk of various illnesses [ 16 , 17 ].…”

Chia seeds oil enriched with phytosterols and mucilage as a cardioprotective dietary supplement towards inflammation, oxidative stress, and dyslipidemia

“…Chia seed gum/mucilage (soluble fiber) constitutes 4%-6% of the seed dry mass, forming a gel when dissolved in water. It can absorb water up to 12 times its weight (21,24,25). Timilsena et al (24) reported xylose, glucose, arabinose, galactose, glucuronic acid, and galacturonic acid as monosaccharide units in the chia seeds gum.…”