2018
DOI: 10.1002/ncp.10227
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Assessing the Evidence in Evidence‐Based Medicine

Abstract: Evidence‐based medicine (EBM) has become a fixture in today's medical practice. Evidence consists of memorialized observations and should be contrasted with dogmatic pronouncements and/or hypotheses. Evidence has varying degrees of reliability. The randomized clinical trial (RCT) or a systematic review of RCTs is accorded the highest level of credibility and expert opinion the lowest. This ranking reflects the internal validity (degree to which factors in the study interfere with the gathering or interpretatio… Show more

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Cited by 17 publications
(16 citation statements)
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References 49 publications
(79 reference statements)
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“…However, in studies of causal inference, the concept of statistical significance should not be a primary concern. In those cases, the efforts must focus on adequately research designing and analysis to avoid bias, control confusion, and consider eventual effect modifications [18,19]. After that, the measures of association and impact should define when a result is significant in the clinical and public health scopes [20].…”
Section: Discussionmentioning
confidence: 99%
“…However, in studies of causal inference, the concept of statistical significance should not be a primary concern. In those cases, the efforts must focus on adequately research designing and analysis to avoid bias, control confusion, and consider eventual effect modifications [18,19]. After that, the measures of association and impact should define when a result is significant in the clinical and public health scopes [20].…”
Section: Discussionmentioning
confidence: 99%
“…In those cases, the efforts must focus on adequately research designing and analysis to avoid bias, control confusion, and consider eventual effect modifications. [18,19]. After that, the measures of association and impact should define when a result is significant in the clinical and public health scopes [20].…”
Section: Discussionmentioning
confidence: 99%
“…However, in studies of causal inference, the concept of statistical significance should not be a primary concern. Before looking at a p-value, the researcher will have to avoid biases and look on conceptual structures to control confusion and consider contexts in which effects can be modified [18,19]. After that, the measures of association and impact are those that must define when a result is significant in the clinical and public health scopes [20].…”
Section: Discussionmentioning
confidence: 99%