This chapter presents an integrative perspective of the relationship between entrepreneurial orientation (EO), international orientation (IO), and performance in the sector of technology-based companies (TBCs) in Portugal. Within the framework of the dynamic capabilities view, the main objectives are to shed light on how EO contributes to the IO and performance of TBCs and how IO contributes to their performance. Based on 253 responses, the relationships between variables were established through a covariance-based structural equation modelling. The results indicate that EO has a direct (positive) effect on international orientation (IO) and an indirect (positive) effect on the performance of TBCs. IO is also found to have a direct (positive) effect on the performance of TBCs. These findings alert managers of TBCs to the relevance of EO and might induce the engagement in technology management. Furthermore, the critical role assumed by IO in this study shows a theoretical contribution to the international entrepreneurship topic and aims to be a reference to the literature.