The Social Cognition and Object Relations Scale-Global Rating Method (SCORS-G) can be used to measure Level of Personality Functioning (LPF). Using a clinical vignette methodology, we examined differential relationships between SCORS-G variables and components of the Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-5) Alternative Model for Personality Disorders (AMPD) as well as general psychiatric functional impairment. This included relationships with (a) Level of Personality Functioning Scale (LPFS; Criterion A of the AMPD), (b) average Criterion B maladaptive trait elevation, and (c) Global Assessment of Functioning (GAF) ratings. By statistically controlling for AMPD pathological trait level and GAF, nuanced relationships between the SCORS-G factor composites and LPFS were found. These results demonstrate that LPF includes significant and specific personality construct variance beyond psychosocial impairment (GAF) and maladaptive trait elevation. These results support using the SCORS-G as a proxy for LPF and suggest ways that clinical practice can be informed by the SCORS-G.