Assessing and Treating Forgetfulness and Cognitive Problems in Adults With HIV

Vance, David E.; Fazeli, Pariya L; Moneyham, Linda; Keltner, Norman L.; Raper, James L.

doi:10.1016/j.jana.2012.03.006

Cited by 37 publications

(41 citation statements)

References 79 publications

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“…For this study, the attrition rate of 25% was rather high but was not all that different from our in person laboratory-based training protocol of 19.30% (Vance et al, 2012). In fact, in our previous study, there was not differential attrition between the speed of processing group and our control group.…”

Section: Discussioncontrasting

confidence: 63%

“…Speed of processing, the ability to quickly process sensory and mental information, has been shown to be compromised in older adults with HIV (e.g., Ciccarelli et al, 2012). The synergistic or additive effects of aging and HIV may cause speed of processing deficits to be even more profound, thus interfering with everyday functioning (Vance, Fazeli, Ross, Wadley, & Ball, 2012). The negative effects of speed of processing deficits on daily activities such as driving are a major safety concern.…”

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confidence: 99%

“…The negative effects of speed of processing deficits on daily activities such as driving are a major safety concern. Few studies focus on promoting successful aging and helping older adults with HIV adapt to such speed of processing deficits (Vance, Fazeli, Moneyham, Keltner, & Raper, 2013). …”

mentioning

confidence: 99%

“…In prior studies, speed of processing training has been successful in improving cognitive function in adults with and without HIV (Ball et al, 2002; Vance et al, 2007; Vance et al, 2012). A recent study of 46 participants with and without HIV revealed that those randomized to the speed of processing training group experienced improvements in speed of processing and everyday functioning (Vance, Fazeli, Ross, Wadley, & Ball, 2012).…”

mentioning

confidence: 99%

“…A recent study of 46 participants with and without HIV revealed that those randomized to the speed of processing training group experienced improvements in speed of processing and everyday functioning (Vance, Fazeli, Ross, Wadley, & Ball, 2012). Speed of processing training involves computerized mental exercises used to improve an individual's ability to identify, locate, and discriminate objects after viewing them for very short periods of time (Ball, Edwards, & Ross, 2007).…”

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confidence: 99%

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Feasibility of a Home-Based Speed of Processing Training Program in Middle-Aged and Older Adults With HIV

Cody

Fazeli

Vance

2015

Journal of Neuroscience Nursing

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There has been much optimism over the positive impact of cART on life expectancy for people with HIV; however, those aging with HIV fear potential day-to-day challenges associated with the development of cognitive deficits. The presence of cognitive deficits has generated major safety concerns as it has been shown to impact driving, mobility, and employment. Given the efficacy of a computerized speed of processing training program administered in the laboratory to older adults and adults with HIV, this study was designed to determine the feasibility of a home-based speed of processing training program in improving cognitive function in middle-aged and older adults with HIV. In this within-subjects pre-post experimental design, twenty middle-aged and older adults (i.e., age 40+) with HIV were administered a brief neuropsychological assessment to gauge their baseline cognitive function before participating in a 10-hour home-based computerized cognitive remediation training program. In addition to self-reported cognitive gains, a six-week posttest indicated significant improvements on the Useful Field of View (UFOV®), a measure of speed of processing and possible transfer to the Timed Instrumental Activities of Daily Living test, a measure of everyday functioning. These findings show that speed of processing training can successfully improve cognitive function in this vulnerable population even when administered in remote settings such as the privacy of one's home.

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Section: Discussioncontrasting

confidence: 63%

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confidence: 99%

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confidence: 99%

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confidence: 99%

mentioning

confidence: 99%

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Feasibility of a Home-Based Speed of Processing Training Program in Middle-Aged and Older Adults With HIV

Cody

Fazeli

Vance

2015

Journal of Neuroscience Nursing

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Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging Literature

Vance

Fazeli

Cheatwood

et al. 2019

Neurocognitive Complications of HIV-Infection

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A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study

Vance,

Fazeli,

Azuero

et al. 2024

AIDS Behav

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Nearly 40% of people with HIV (PWH) experience HIV-associated Neurocognitive Disorder (HAND). In this 3-group efficacy study, 216 PWH 40 + years with HAND or borderline HAND were randomized to either: (1) 10 h of SOP training (n = 70); (2) 20 h of SOP training (n = 73), or (3) 10 h of Internet navigation training (n = 73; contact control group). Participants were administered a measure of SOP [i.e., the Useful Field of View Test (UFOV®)] at baseline, at posttest immediately after training, and at year 1 and year 2 follow up. Intent-to-treat linear mixed-effect models with subject-specific intercept and slope were fitted to estimate between-group mean differences at the follow-up time-points. At the post-intervention time-point, small beneficial SOP training effects were observed for the 10-h group in UFOV® total (d = 0.28, p = 0.002). Effects were of larger magnitude for the 20-h group in these same outcomes [UFOV® total (d = 0.43, p < 0.001)]. These results indicated better benefit with more training. No intervention effect was observed at year 1. At year 2, beneficial effects of small magnitude were observed again in the 10-h group [UFOV® total (d = 0.22, p = 0.253)] with larger small-to-moderate magnitude in the 20-h group [UFOV® total (d = 0.32, p = 0.104)]. This study suggests that SOP training can improve a key indicator of this cognitive performance and that treatment gains are small-to-moderate over a two-year period. Prior literature suggests slower SOP is predictive of impairment in everyday functioning in older PWH; such an approach could potentially improve everyday functioning in PWH.

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Assessing and Treating Forgetfulness and Cognitive Problems in Adults With HIV

Cited by 37 publications

References 79 publications

Feasibility of a Home-Based Speed of Processing Training Program in Middle-Aged and Older Adults With HIV

Feasibility of a Home-Based Speed of Processing Training Program in Middle-Aged and Older Adults With HIV

Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging Literature

A 2-Year Longitudinal Randomized Control Trial of Speed of Processing Cognitive Training in Aging Adults with HIV-Associated Neurocognitive Disorder: Results of the Think Fast Study

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