Assessing accumulation and biliary excretion of naphthenic acids in yellow perch exposed to oil sands-affected waters

Heuvel, Michael R. van den; Hogan, Natacha S.; MacDonald, Gillian Z.; Berrué, Fabrice; Young, Rozlyn F.; Arens, Collin J.; Kerr, Russell G.; Fedorak, Phillip M.

doi:10.1016/j.chemosphere.2013.10.021

Cited by 13 publications

(11 citation statements)

References 30 publications

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“…Previous experiments conducted at Demonstration and South Bison Ponds using yellow perch and rainbow trout also reported CYP1A induction corresponding to bile fluorescence at phenanthrene wavelengths similar to those observed in the present study. In the perch studies, the high responses observed in both CYP1A induction and PAH equivalent concentrations at South Bison Pond were attributed to unextracted oil sands material used in the construction of the pond basin.…”

Section: Discussionsupporting

confidence: 90%

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Sublethal effects of aged oil sands–affected water on white sucker (Catostomus commersonii)

Arens

Hogan

Kavanagh

et al. 2015

Enviro Toxic and Chemistry

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To investigate impacts of proposed oil sands aquatic reclamation techniques on benthic fish, white sucker (Catostomus commersonii Lacépède, 1803) were stocked in 2 experimental ponds-Demonstration Pond, containing aged fine tailings capped with fresh water, consistent with proposed end-pit lake designs, and South Bison Pond, containing aged unextracted oil sands material-to examine the effects of unmodified hydrocarbons. White sucker were stocked from a nearby reservoir at both sites in May 2010 and sampled 4 mo later to measure indicators of energy storage and utilization. Comparisons were then made with the source population and 2 reference lakes in the region. After exposure to aged tailings, white sucker had smaller testes and ovaries and reduced growth compared with the source population. Fish introduced to aged unextracted oil sands material showed an increase in growth over the same period. Limited available energy, endocrine disruption, and chronic stress likely contributed to the effects observed, corresponding to elevated concentrations of naphthenic acids, aromatic compounds in bile, and increased CYP1A activity. Because of the chemical and biological complexity of these systems, direct cause-effect relationships could not be identified; however, effects were associated with naphthenic acids, polycyclic aromatic hydrocarbons, ammonia, and high pH. Impacts on growth have not been previously observed in pelagic fishes examined in these systems, and may be related to differences in sediment interaction.

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Section: Discussionsupporting

confidence: 90%

“…Excitation/emission wavelengths used were that of phenanthrene and benzo[ a ]pyrene (256/380 nm and 380/430 nm, respectively). The equivalent concentrations were derived by summing the area of all metabolite peaks that eluted after the first 3 min of the run and dividing by the slope of the respective standard curve .…”

Section: Methodsmentioning

confidence: 99%

Sublethal effects of aged oil sands–affected water on white sucker (Catostomus commersonii)

Arens

Hogan

Kavanagh

et al. 2015

Enviro Toxic and Chemistry

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“…The pattern of physiological response in white sucker from the Athabasca River differed from the pattern observed for fish exposed to oil sands process-affected water [19,22]. In previous studies where yellow perch and white sucker were exposed in situ to oil sands process-affected water for a summer season, male fish exhibited reduced gonad development [15,19].…”

Section: Discussionmentioning

confidence: 78%

“…This technique involved HPLC-fluorescence analysis of diluted bile at phenanthrene (excitation 256 nm and emission 380 nm) and benzo[a]pyrene (excitation 380 nm and emission 430 nm) wavelengths. Bile naphthenic acids were evaluated using the methods of van den Heuvel et al [22] with modifications. Bile naphthenic acids were deconjugated using ethanolic potassium hydroxide and extracted with methyl tert-butyl ether.…”

Section: Tissue Analysesmentioning

confidence: 99%

“…Because of the interference of high levels of fatty acids in bile that have the same m/z ratio as many common naphthenic acids, a subset of ions was chosen not typically present in bile. Six ions were chosen for analysis (m/z 209.1536, 211.1693, 235.1693, 237.1849, 239.2006, 261.1849), and the concentration of total naphthenic acids was calculated for each ion against a purified naphthenic acid mixture and those concentrations averaged to give the estimated naphthenic acid concentration in bile [22]. Recovery of d 31 palmitic acid averaged 85.9%, and naphthenic acid concentrations in bile were corrected for individual sample recovery.…”

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confidence: 99%

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Population impacts in white sucker (Catostomus commersonii) exposed to oil sands–derived contaminants in the Athabasca River

Arens

Hogan

et al. 2017

Enviro Toxic and Chemistry

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Biological and chemical endpoints were measured in white sucker collected downstream of Athabasca oil sands developments (AB, Canada) and compared with those at Calling Lake (AB, Canada), a reference location upstream of the Athabasca oil sands deposit. Naphthenic acid concentrations were also measured at 14 sites in the Athabasca River watershed. Concentrations of naphthenic acids were elevated in tributaries adjacent to oil sands mining developments. Tributary naphthenic acid profiles were more similar to aged oil sands process water than samples from the Athabasca River, suggesting an influence of tailings in the tributaries. White sucker showed higher energy storage in the Athabasca River as indicated by significantly higher condition and liver size. White sucker were not investing that energy into reproductive effort as measured by gonad size and fecundity, which were significantly reduced relative to the reference location. White sucker showed increased exposure to polycyclic aromatic hydrocarbons as indicated by hepatic cytochrome P4501A (CYP1A) activity and fluorescent bile metabolites, as well as higher concentrations of naphthenic acids in bile. Cadmium, copper, nickel, and selenium were also elevated in white sucker liver tissue compared with the reference location. Based on the exposure profile and response pattern observed, effects on energy storage and utilization in white sucker from the Athabasca River most likely resulted from exposure to polycyclic aromatic hydrocarbons derived from petrogenic and pyrolytic sources. Environ Toxicol Chem 2017;36:2058-2067. © 2017 SETAC.

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A critical review of the ecological status of lakes and rivers from Canada's oil sands region

Arciszewski

Hazewinkel

Dubé

2021

Integr Envir Assess & Manag

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We synthesize the information available from the peer‐reviewed literature on the ecological status of lakes and rivers in the oil sands region (OSR) of Canada. The majority of the research from the OSR has been performed in or near the minable region and examines the concentrations, flux, or enrichment of contaminants of concern (CoCs). Proximity to oil sands facilities and the beginning of commercial activities tend to be associated with greater estimates of CoCs across studies. Research suggests the higher measurements of CoCs are typically associated with wind‐blown dust, but other sources also contribute. Exploratory analyses further suggest relationships with facility production and fuel use data. Exceedances of environmental quality guidelines for CoCs are also reported in lake sediments, but there are no indications of toxicity including those within the areas of the greatest atmospheric deposition. Instead, primary production has increased in most lakes over time. Spatial differences are observed in streams, but causal relationships with industrial activity are often confounded by substantial natural influences. Despite this, there may be signals associated with site preparation for new mines, potential persistent differences, and a potential effect of petroleum coke used as fuel on some indices of health in fish captured in the Steepbank River. There is also evidence of improvements in the ecological condition of some rivers. Despite the volume of material available, much of the work remains temporally, spatially, or technically isolated. Overcoming the isolation of studies would enhance the utility of information available for the region, but additional recommendations for improving monitoring can be made, such as a shift to site‐specific analyses in streams and further use of industry‐reported data. Integr Environ Assess Manag 2022;18:361–387. © 2021 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

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Assessing accumulation and biliary excretion of naphthenic acids in yellow perch exposed to oil sands-affected waters

Cited by 13 publications

References 30 publications

Sublethal effects of aged oil sands–affected water on white sucker (Catostomus commersonii)

Sublethal effects of aged oil sands–affected water on white sucker (Catostomus commersonii)

Population impacts in white sucker (Catostomus commersonii) exposed to oil sands–derived contaminants in the Athabasca River

A critical review of the ecological status of lakes and rivers from Canada's oil sands region

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