AsPNA

Yap, Hui-Kim; Chiu, Man Chun; Bagga, Arvind; Safouh, Hesham

doi:10.1007/978-3-642-27843-3_71-1

Cited by 1 publication

(2 citation statements)

References 81 publications

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“…Yap (Singapore) has published literature that depicts the two leading causes of end-stage renal failure in paediatric patients to be glomerulonephritis (33.4%) and congenital renal malformations (obstructive uropathy, renal hypoplasia/ dysplasia and reflux nephropathy) (37.9%). 17 Even so, this statistic is grouped as a whole spectrum of diseases and does not specifically focus on PUV. Looking at the dataset from this study, a quarter of our patients have renal failure, and this demonstrates the impact of PUV.…”

Section: Discussionmentioning

confidence: 99%

“…The amount of published literature on PUV from Southeast Asian countries is scant. Yap (Singapore) has published literature that depicts the two leading causes of end‐stage renal failure in paediatric patients to be glomerulonephritis (33.4%) and congenital renal malformations (obstructive uropathy, renal hypoplasia/dysplasia and reflux nephropathy) (37.9%) 17 . Even so, this statistic is grouped as a whole spectrum of diseases and does not specifically focus on PUV.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Outcome of boys with posterior urethral valves from a single tertiary hospital in Singapore

Chan

et al. 2022

ANZ Journal of Surgery

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Introduction Posterior urethral valve (PUV) is the most common congenital cause of bladder outflow obstruction in male infants. Despite timely treatment, renal damage can still occur in the long‐term leading to chronic kidney disease (CKD). Methods A retrospective review of all PUV patients in a single tertiary institution between April 1998 and July 2019 was conducted to analyze their presentations, management and outcomes. Long‐term renal function, radiologic scans and somatic growth were evaluated. Results A total of 16 patients were included in this study. Two patients who defaulted all follow‐ups were excluded. Seven patients (43.7%) presented in the antenatal period; four patients (25%) presented in the neonatal period and five patients (31.3%) presented in the post‐neonatal period. Primary transurethral fulguration of valves was done in 13 patients, while three had vesicostomies as the primary procedure. Three patients had associated anterior urethral valves (AUV), which were treated endoscopically. Nine boys had additional procedures for diversion and undiversion, VUR, non‐functioning kidney and clean intermittent catheterization. Ten patients had urodynamic studies performed, of which eight patients received anticholinergic therapy. Eleven patients had DMSA scans, of which three patients had a normal study and eight patients showed unilateral reduced function. Four patients were diagnosed with CKD on long‐term follow‐up duration over 5 years. All patients were shown to have good somatic growth. Conclusion Patients with PUV can suffer from complications despite primary treatment. In our small cohort, a quarter of our patients developed CKD on follow‐up. Thus, patients need long‐term follow‐up to optimize bladder and renal function.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%