Aspiration cytology of the endometrium: Office and hospital sampling procedures

Isaacs, John H.; Wilhoite, Robert W.

doi:10.1016/s0002-9378(16)33742-5

Cited by 45 publications

(14 citation statements)

References 7 publications

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“…The inadequacy rates obtained by using the Gravlee Jet Washer have been reported by Dowling et al, [7] Afonso et al, [8] and Richart et al, [9] to be 27, 1.66, and 9.6% respectively. Using the Isaac endosampler [10] gave a 2.5% inadequacy rate which was very close to the rates given by Liza et al [11] (2.8%) and the present study (6.6%).…”

Section: Discussionsupporting

confidence: 92%

“…In the present study too, the insemination cannula was used Dowling et al [7] Gravlee jet washer 27 Atrophic endometrium, recent abortion Isaacs et al [10] Isaac endosampler 2.5 Drying artefact, failure of insertion Afonso [8] Gravlee jet washer 1.6 Cervical stenosis, distorted endocervical canal Richart et al [9] Gravlee jet washer 9.6 Cervical stenosis Liza et al [11] Insemination canula 2.8 Post menopausal age Present study Insemination cannula 6.6 Atrophic endometrium and technical failure [13] Gravlee jet washer 88.1 98.6 Byrne [14] Endocyte 92 100 Bistoletti et al [5] Endopap 97 84 Liza et al [11] Insemination which gave a sensitivity of 83.3% and a specificity of 95.4%. Similar studies were also done by An-Foraker et al, [4] Favre et al, [13] Byrne [14] and Bistoletti and Hjerpe [5] by using different devices such as the Isaac cell sampler, [10] Gravlee jet washer, [7] Endocyte, [14] and Endopap.…”

Section: Discussionmentioning

confidence: 95%

“…The various causes of inadequacy of cellular yield in EAC [7][8][9][10][11] have been summarized in Table 3. These include atrophic endometrium, stenosis of cervical canal, difficulty in insertion, drying artifact, and poor technique.…”

Section: Discussionmentioning

confidence: 99%

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Cytological assessment of endometrial washings obtained with an insemination cannula and its histological correlation

Malik

Agarwal

Tandon

2008

J Cytol

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Background: Endometrial cytopathology is a powerful tool for the detection of a wide variety of benign atypias, infl ammatory changes, and infectious organisms. It is also helpful for the cytohormonal evaluation of patients and the detection of endometrial malignancies. Aims:The present study was carried out to assess the sensitivity and specifi city of endometrial cytology performed by using an insemination cannula. Materials and Methods:Endometrial aspiration using an insemination cannula was done in 60 cases who presented with dysuterine bleed, infertility, or postmenopausal bleed. The cytological evaluation of endometrial smears was correlated with histopathological fi ndings with reference to cyclic endometrium, atypical hyperplasia, and endometrial malignancies.Results: There were 35 patients in the reproductive and 25 in the menopausal age groups. The sample was inadequate in four cases but there was an overall 100% correlation between cytological and histological fi ndings of cyclic endometrium, atypical hyperplasia, and endometrial malignancy. The sensitivity and specifi city of endometrial aspiration was 83.3 and 95.4% respectively, with two false negative and false positive cases.Conclusions: Endometrial aspiration cytology was found to be a safe outpatient procedure in the diagnosis of normal and abnormal endometrium for patients of all ages.The present study emphasizes the need for endometrial screening in postmenopausal patients to enable the detection of endometrial malignancies at an early stage.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 95%

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Cytological assessment of endometrial washings obtained with an insemination cannula and its histological correlation

Malik

Agarwal

Tandon

2008

J Cytol

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“…23 After occlusion of the external os with the obturator, the sampling was performed by 10 to 12 quick aspirations with the pis ton of the syringe. In about 75 percent of the subjects, regardless of age or instru ment used, the endometrial sampling could be performed without the use of a tenac ulum.…”

Section: Endocervical Aspiration Smear Frommentioning

confidence: 99%

Screening of Asymptomatic Women for Endometrial Cancer

Koss

Schréiber

Oberlander

et al. 1981

CA: A Cancer Journal for Clinicians

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“…[12] Isaac reported the inadequacy rate of 2.5%. [13] In the study conducted by Afonso et al, using Gravlee jet washer, the inadequacy rate was 1.6% and Liza et al 2.8%. [9,14] Samina Ashraf and Farhat Jabeen using Karman's cannula reported an inadequacy rate of 6%.…”

Section: Discussionmentioning

confidence: 99%

Endometrial Aspiration Cytology by Karman's Cannula with Histopathological Correlation

2017

IJSR

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Introduction: Dilatation and curettage is the commonly used diagnostic technique to assess endometrial normalcy and pathology. Endometrial aspiration cytology on the other hand is a simple outpatient procedure without the cost of hospitalization, operation theatre & risk of anesthesia inherent in dilatation and curettage. Objectives: The present study was carried out carried out to assess the sensitivity and specificity of endometrial cytology performed by using Karman's cannula compared with histopathology. Materials & Method: Endometrial aspiration was done using 4mm Karman's cannula in 144 cases who presented with dysfunctional uterine bleeding, postmenopausal bleed and infertility prior to dilatation and curettage. The cytological diagnosis was correlated with histopathological diagnosis. Results: Adequate material was obtained in 93.06% of cases on aspiration. Proliferative endometrium was the most common pattern (38.2%) observed. There was an overall 100% correlation in case of secretory endometrium, atypical hyperplasia and endometrial carcinoma and 90.9% correlation in case of proliferative endometrium between cytological and histopathological findings. The sensitivity and specificity of endometrial aspiration was 88.31% and 100% respectively. Conclusion: Endometrial aspiration was found to be simple, safe, cost effective, well tolerated outpatient procedure which can be offered to patients as an outpatient sampling technique.

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Aspiration cytology of the endometrium: Office and hospital sampling procedures

Cited by 45 publications

References 7 publications

Cytological assessment of endometrial washings obtained with an insemination cannula and its histological correlation

Cytological assessment of endometrial washings obtained with an insemination cannula and its histological correlation

Screening of Asymptomatic Women for Endometrial Cancer

Endometrial Aspiration Cytology by Karman's Cannula with Histopathological Correlation

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