Aspiration Biopsy Cytology (ABC). Its Use in Diagnosis of Lesions of the Prostate Gland

Fine Needle Aspiration Biopsy vs. Ultrasound-Guided Transrectal Random Core Biopsy of the Prostate

“…These results showed that in 80% of all cases a direct correlation was found with the Gleason grade. 12,14 In our study FNAB had a sensitivity of 98%, far exceeding that of core needle biopsy (91%). Numerous studies over the last 15 years have shown that in the hands of experienced cytopathologists, FNAB may be as helpful as core biopsy.…”

The continuing role of fine-needle aspiration of the prostate gland into the 21st century: A tribute to Torsten Löwhagen

“…According to The John Hopkins Experience, only 55% patients who met the criteria for RP had tumors that were organ confined, and in approximately 10% of cases the disease involved regional lymph nodes or seminal vesicles. 97 Correlation of cytological grading with the Gleason score has been published elsewhere 59,63,67,70,72,[77][78] and the accuracy of digitally guided transrectal FNA has been tested in comparative studies with thick and ultrasound-guided thinneedle core biopsies; both methods have equal sensitivity and specificity, and false positives are rare to nonexistent: 7,8,[15][16]27,30,[32][33]36,[55][56]59,[61][62][68][69]71,73,76,92,93,95 FNA passed this scrutiny with honors and was deemed suitable to perform a confident diagnosis of prostate cancer. According to Tannenbaum,78 when an appropriate number of samples are obtained from palpable abnormal prostates, the detection rate for cancer is the same for both aspiration and core biopsies.…”

“…Several authors [9][10]18,27,30,39,[42][43]47,49,55 have used FNA of the prostate to evaluate the response to hormonal treat-ment. Leinstenschneider and Nagel 39 established six grades of regression and Andersson established four grades.…”

A Correlative Study Between Transrectal Fnac And Histology Of The Prostate For The Detection Of Prostate Carcinoma.

“…Similar observations have been reported by Couture et al, Kline et al, Ljung et al, Koltz et al and Brenner et al . [16,17,18,19,20] Al Abadi reviewed the pertinent literature, notably papers by Bruin et al and his own previous publication and concluded that FNA was more accurate, less tedious to the patient and much cheaper than the core biopsy. [21] Hermida et al reported sensitivity of 96%, specificity 96%, positive predictive value 91%, negative predictive value 93% and efficacy 92%.…”