Aspergillosis: A disease with many faces

Miller, Wallace T.

doi:10.1016/s0037-198x(96)80040-x

Cited by 40 publications

(21 citation statements)

References 43 publications

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“…Immediate hypersensitivity may also be seen as a reaction to Aspergillus, where Aspergillus acts as an inhaled antigen similar to other organic dusts producing an allergic alveolitis (hypersensitivity pneumonitis). This reaction is mediated by type I (IgE) with contributions from cell-mediated (type IV) and immune complex (type III), and can be seen in some asthmatic patients inhaling a heavy spore load [20,21].…”

Section: Immune Considerationsmentioning

confidence: 99%

Aspergillus in the lung: diverse and coincident forms

Buckingham

Hansell

2003

Eur Radiol

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Pulmonary disease caused by the fungus Aspergillus has traditionally been regarded as belonging to one of the following, apparently distinct, entities: saprophytic aspergilloma; allergic bronchopulmonary aspergillosis (ABPA); and invasive aspergillosis (IPA); which may be further categorised as angioinvasive, acute or chronic airway invasive) [1]. It is not always obvious that there is overlap between these entities, and that in any given patient more than one Aspergillus-related pathological process can co-exist [2]. The aim of this article is to review the clinical and imaging features of the main categories of Aspergillus-related pulmonary disease and, in particular, to highlight the overlap between them.

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Section: Immune Considerationsmentioning

confidence: 99%

Aspergillus in the lung: diverse and coincident forms

Buckingham

Hansell

2003

Eur Radiol

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“…There is a heterogeneous spectrum of radiological findings in invasive pulmonary aspergillosis including round pneumonic infiltrates, peripheral wedge-shaped lesions and the typical ''halo sign'' around pneumonic infiltrates, which can be detected by high resolution CT [13,14,24,36,47,61,93,97,103]. The air crescent sign (also known as ''Monod's sign'') is a late marker that develops with the bone marrow recovery [14].…”

Section: Radiological Findings In Children With Invasive Aspergillosismentioning

confidence: 99%

Clinical manifestations and diagnosis of invasive aspergillosis in immunocompromised children

Müller

Trusen

Weig

2002

European Journal of Pediatrics

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“…Diagnosis is based on characteristic clinical symptoms and demonstration of antigen-specific IgGs (1)(2)(3)(4). Antigen exposure also elicits production of IgGs in other pulmonary diseases, such as invasive aspergillosis (5,6 ), allergic bronchopulmonary aspergillosis (ABPA) 3 (7 ), and ABPA in cystic fibrosis (8 ). A widely used method to detect specific IgG in clinical laboratories is the immunoprecipitation technique.…”

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confidence: 99%