Aseptic loosening of Boneloc R cemented hip prostheses

Wedderkopp, Niels; Andersen-Ranberg, F; Andersen, Michael Brun; Termansen, Niels B.

doi:10.1007/s002640050126

Cited by 9 publications

(4 citation statements)

References 10 publications

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“…Long-term endurance of the cement mantle is a key factor for the survival of cemented hip prostheses. Current protocols to characterize acrylic bone cements appear unsuitable when predicting the actual clinical outcome of bone cements [14][15][16][17]. The static and dynamic mechanical properties of bone cement have been investigated extensively in the past, using various testing methods [10].…”

Section: Discussionmentioning

confidence: 99%

“…Boneloc and CMW3 are examples of bone cement that were introduced to clinical practice after successfully passing all tests described in the ISO 5833. Despite this, Boneloc exhibited a dramatic failure rate (as high as 60 per cent after 0.5-3 years [14][15][16]). Similarly, CMW3 had a higher failure rate than most cements in use (as high as 17 per cent at ten years [17,18]).…”

Section: Introductionmentioning

confidence: 99%

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Effect of long-term physiological activity on the long-term stem stability of cemented hip arthroplasty: in vitro comparison of three commercial bone cements

Bialoblocka-Juszczyk

Cristofolini

Erani

et al. 2009

Proc Inst Mech Eng H

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Long-term endurance of the cement mantle is fundamental for the survival of cemented hip prostheses. Current protocols to characterize bone cements are unsuitable to predict the actual clinical outcome. The aim of this study was to assess if it is possible to rank cement types having diverse clinical outcome by using a simplified in vitro physiological test. Composite femurs were implanted with identical stems (Lubinus-SPII), using different commercial cement types: CMW1 to represent cement with poor clinical outcome; Simplex-P and Cemex-RX to represent cements with a positive clinical outcome. Implanted femurs were subjected to a validated protocol that simulated a demanding but physiological loading spectrum. Inducible micromotions and permanent migrations were recorded throughout the test. After test completion, the cement mantles were sectioned and inspected with dye penetrants to quantify the fatigue-induced cracks. Micromotions did not differ significantly between cement types (possibly because a successful prosthesis was chosen that is very stable in the host bone). Significant differences were observed in terms of cement cracks: CMW1 induced significantly more numerous and larger cracks than Simplex-P and Cemex-RX; no difference was observed between Simplex-P and Cemex-RX. This indicates that this protocol: (a) can discriminate between 'good' and 'bad' cements and (b) yields consistent results when comparable cements are tested. The proposed protocol overcomes the limitations of existing standardized material tests for bone cements. New cements can be assessed in comparison with other cements with known (positive/negative) clinical outcome, tested with the same protocol.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of long-term physiological activity on the long-term stem stability of cemented hip arthroplasty: in vitro comparison of three commercial bone cements

Bialoblocka-Juszczyk

Cristofolini

Erani

et al. 2009

Proc Inst Mech Eng H

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“…Unfortunately, the introduction of new technologies and devices is not a benign process, and even subtle changes to existing implants can affect patient outcomes. [1][2][3][4][5] In order to minimize negative outcomes from implant design innovation, many orthopaedic researchers advocate for the phased introduction of new technologies. 6 Radiostereometric analysis (RSA) completed early in the process of the clinical evaluation of a new component is a key part of phased introduction of a new implant.…”

Section: Introductionmentioning

confidence: 99%

“…Unfortunately, the introduction of new technologies and devices is not a benign process, and even subtle changes to existing implants can affect patient outcomes. 1 - 5 In order to minimize negative outcomes from implant design innovation, many orthopaedic researchers advocate for the phased introduction of new technologies. 6 …”

Section: Introductionmentioning

confidence: 99%

Randomized controlled trial comparing traditional versus enhanced-fixation designs of a novel cemented total knee arthroplasty tibial component

Turgeon,

Vasarhelyi,

Howard

et al. 2024

Bone Jt Open

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AimsA novel enhanced cement fixation (EF) tibial implant with deeper cement pockets and a more roughened bonding surface was released to market for an existing total knee arthroplasty (TKA) system.This randomized controlled trial assessed fixation of the both the EF (ATTUNE S+) and standard (Std; ATTUNE S) using radiostereometric analysis.MethodsOverall, 50 subjects were randomized (21 EF-TKA and 23 Std-TKA in the final analysis), and had follow-up visits at six weeks, and six, 12, and 24 months to assess migration of the tibial component. Low viscosity bone cement with tobramycin was used in a standardized fashion for all subjects. Patient-reported outcome measure data was captured at preoperative and all postoperative visits.ResultsThe patient cohort mean age was 66 years (SD seven years), 59% were female, and the mean BMI was 32 kg/m2 (SD 6 kg/m2). Mean two-year subsidence of the EF-TKA was 0.056 mm (95% confidence interval (CI) 0.025 to 0.086) versus 0.006 mm (95% CI -0.029 to 0.040) for the Std-TKA, and the two-year maximum total point motion (MTPM) was 0.285 mm (95% upper confidence limit (UCL) ≤ 0.363) versus 0.346 mm (95% UCL ≤ 0.432), respectively, for a mean difference of -0.061 mm (95% CI -0.196 to 0.074). Inducible displacement also did not differ between groups. The MTPMs between 12 and 24 months for each group was below the published threshold of 0.2 mm for predicting early aseptic loosening (p < 0.001 and p = 0.001, respectively).ConclusionBoth the enhanced fixation and the standard tibial implant design showed fixation with a predicted low risk of long-term aseptic loosening.Cite this article: Bone Jt Open 2024;5(1):20–27.

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Bone loss around failed femoral implant measured by dual-energy X-ray absorptiometry

Venesmaa

Kröger

Miettinen

et al. 2000

Journal of Orthopaedic Science

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Aseptic loosening of Boneloc R cemented hip prostheses

Cited by 9 publications

References 10 publications

Effect of long-term physiological activity on the long-term stem stability of cemented hip arthroplasty: in vitro comparison of three commercial bone cements

Effect of long-term physiological activity on the long-term stem stability of cemented hip arthroplasty: in vitro comparison of three commercial bone cements

Randomized controlled trial comparing traditional versus enhanced-fixation designs of a novel cemented total knee arthroplasty tibial component

Bone loss around failed femoral implant measured by dual-energy X-ray absorptiometry

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