Ascorbic acid and choline chloride: A new natural deep eutectic solvent for extracting tert-butylhydroquinone antioxidant

Liu, Wei; Zhang, Kang-Di; Chen, Jingnan; Yu, Jingjing

doi:10.1016/j.molliq.2018.03.092

Cited by 59 publications

(15 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results indicated that the DESs made from ChCl and ethylene glycol (1:2 M ratio) showed a higher extraction efficiency of TBHQ (close to 100%) than ChCl/propylene glycol (1:2 M ratio) and ChCl/glycerol (1:2 M ratio). Subsequently, a novel natural deep eutectic solvent (NADES) synthesized by ChCl and ascorbic acid was also used for UALLME of TBHQ from edible oils [12], coupled with the HPLC-UV analysis. The results showed that the NADES consisting of ChCl and ascorbic acid (2:1 M ratio) exhibited a higher extraction efficiency (close to 100%) and excellent protection ability for TBHQ during the extraction process.…”

Section: Dess For the Extraction Of Synthetic Phenolicsmentioning

confidence: 99%

“…It was found that phenolic DES made from ChCl and p-cresol (1:2 M ratio) showed the best extraction efficiency at room temperature for all tocopherols isomers (alpha, gamma, and delta-tocopherols) due to the strong π−π interaction between the phenolic DES and tocopherols ( Figure 2). for UALLME of TBHQ from edible oils [12], coupled with the HPLC-UV analysis. The results showed that the NADES consisting of ChCl and ascorbic acid (2:1 M ratio) exhibited a higher extraction efficiency (close to 100%) and excellent protection ability for TBHQ during the extraction process.…”

Section: Dess For the Extraction Of Natural Phenolicsmentioning

confidence: 99%

“…The viscosity of the DESs can be adjusted by changing the concentrations and mole ratio of HBAs and HBDs as well as temperature during the extraction. Liu et al found that the viscosity of a DES composed of ascorbic acid and choline chloride (ChCl) decreased rapidly from the original 3.799 mPa•s to 0.1203 mPa•s with the addition of 10% water (v/v) [12]. The viscosity of the DES (ascorbic acid/ChCl/water) also decreased by 80% when the temperature was elevated from 30 • C to 70 • C. In addition, the polarity of DESs, which is very close to that of most organic polar solvents, is related to their components and the addition of a small portion of water.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Application of Deep Eutectic Solvents in Food Analysis: A Review

Chen

Wang

et al. 2019

Molecules

Self Cite

View full text Add to dashboard Cite

Deep eutectic solvents (DESs) have emerged recently as new and green solvents. DESs can be used for extraction and separation of both inorganic metallic components and organic compounds such as phenolic compounds, flavonoids, sugars, and aromatic amines from food samples. DESs possess a tunable property simply by adjusting the ratio of hydrogen bond acceptors to the hydrogen bond donors. As a green extraction medium, DESs have various applications in the pretreatment process and improve the efficiency of different food analyses. This review summarizes the findings of recent studies on the development, production, application, and efficacy of DESs in the pretreatment process of various food analyses.

show abstract

Section: Dess For the Extraction Of Synthetic Phenolicsmentioning

confidence: 99%

Section: Dess For the Extraction Of Natural Phenolicsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Application of Deep Eutectic Solvents in Food Analysis: A Review

Chen

Wang

et al. 2019

Molecules

Self Cite

View full text Add to dashboard Cite

show abstract

“…DESs possess tunable solvent properties that make them highly efficient in extracting compounds from different chemical classes. With respect to SAs, tert-butylhydroquinone is the only analyte that has been determined in vegetable oils with the extraction procedures based on the use of ChCl:ascorbic acid, 33 ChCl:sesamol 34 and ChCl:ethylene glycol 35 compositions. However, as far as we know, there is no DES-based extraction method reported in the literature for alkyl gallates.…”

Section: Introductionmentioning

confidence: 99%

Vortex-Assisted Deep Eutectic Solvent-Based Liquid-Liquid Microextraction for the Analysis of Alkyl Gallates in Vegetable Oils

Çabuk

Yılmaz

Yıldız

2019

ACSi

View full text Add to dashboard Cite

This study investigates the feasibility of using hydrophilic deep eutectic solvent (DES) as green and effective extractant for the extraction and preconcentration of alkyl gallates from vegetable oils. In a typical experiment, 120 µL of choline chloride:ethylene glycol DES was added to 1.0 g of oil sample which was previously diluted with 1 mL of n-hexane. The extraction was accelerated by vortex stirring of the two phases. At this stage, hydrogen bonding interactions between the phenyl hydroxyls of alkyl gallates and chloride anion of choline salt were likely the main forces driving the extraction. After extraction, the analytes in the DES phase were separated and determined by high-performance liquid chromatography with ultraviolet detection. The method detection limits for propyl gallate and octyl gallate were 2.1 and 4.6 µg kg -1 , respectively. The precision of the method varied between 4.6-6.4% (intra-day) and 5.4-7.5% (inter-day). The recoveries (accuracies) obtained from spiked vegetable oil samples were in the range of 78-106%.

show abstract

“…12 For complicated sample matrixes, different pretreatment processes have been employed before HPLC analysis of Sudan I, such as conventional liquid-liquid extraction, 12 solid-phase microextraction, and liquid-liquid microextraction. 13 In recent years, liquid-liquid microextraction techniques based on deep eutectic solvents have attracted wide attention, such as ultrasonic-assisted liquid-liquid microextraction technique (UALLME), [14][15][16] air-assisted liquid-liquid microextraction (AALLME), 17 and vortex-assisted liquid-liquid microextraction (VALLME). 18 Deep eutectic solvents are new green solvents that are readily available owing to their simple preparation.…”

Section: Introductionmentioning

confidence: 99%